Tegoprazan
- CAS No.
- 942195-55-3
- Chemical Name:
- Tegoprazan
- Synonyms
- 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide;1H-Benzimidazole-5-carboxamide, 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-;RQ-4;CJ 12420;Tegoprazan;RQ-00000004;Tegoprazan API;Tegoprazan (B);Tegoprazan Emixustat HCL Hydrochloride;pentagastrin,Proton Pump,acid,Tegoprazan,gastric,secretion,inhibit,Inhibitor
- CBNumber:
- CB83159891
- Molecular Formula:
- C20H19F2N3O3
- Molecular Weight:
- 387.38
- MDL Number:
- MFCD30533430
- MOL File:
- 942195-55-3.mol
| Boiling point | 596.5±50.0 °C(Predicted) |
|---|---|
| Density | 1.371±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble |
| form | A solid |
| pka | 9.73±0.30(Predicted) |
| FDA UNII | W017G7IF4S |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| NFPA 704 |
|
Tegoprazan price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | T145030 | Tegoprazan | 942195-55-3 | 0.5mg | $235 | 2021-12-16 | Buy |
| TRC | T145030 | Tegoprazan | 942195-55-3 | 5mg | $2365 | 2021-12-16 | Buy |
| ChemScene | CS-0014702 | Tegoprazan 98.85% | 942195-55-3 | 50mg | $1450 | 2021-12-16 | Buy |
| ChemScene | CS-0014702 | Tegoprazan 98.85% | 942195-55-3 | 100mg | $2250 | 2021-12-16 | Buy |
| ChemScene | CS-0014702 | Tegoprazan 98.85% | 942195-55-3 | 5mg | $300 | 2021-12-16 | Buy |
Tegoprazan Chemical Properties,Uses,Production
Drug Approval
Tegoprazan was approved by the Ministry of Food and Drug Safety (MFDS) for marketing in July 2018 for the treatment of gastroesophageal reflux disease and erosive esophagitis. Tegoprazan was originally developed by Pfizer. In 2008, it was licensed to RaQualiaPharma (separated from Pfizer) for joint development. In 2014, Tegoprazan was licensed to CJHealthCare by RaQualiaPharma. Finally, CJHealthCare was successfully developed and marketed in Korea. The drug was first marketed in South Korea.
Medical efficacy
Tegoprazan is medicine for treating gastroesophageal reflux disease and erosive esophagitis. Proton pump hydrogen ion/potassium ion exchange ATPase is the main pharmacological target for the treatment of gastric acid-related diseases. Potassium-competitive acid blocker (P-CAB) can inhibit gastric acid secretion by competitively binding to K+ with H+/K+-ATPase. Research finds that Tegoprazan is such a potassium-competitive acid blocker and is considered to be the most advanced drug for treating gastroesophageal reflux disease, because proton pump inhibitors are the most commonly used drugs for treating gastroesophageal reflux disease.
Uses
Tegoprazan is used for remedying and treating nocturnal acid breakthrough symptoms, such as GERD, ulcer, Barrett''s esophagus, and heartburn.
Tegoprazan Preparation Products And Raw materials
Raw materials
Preparation Products
Tegoprazan Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 3000 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@airuikechemical.com | China | 994 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15932 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Kindchem(Nanjing)Co.,Ltd | +86-025-025-85281586 +8618651653755 | sales@kindchem.cn | China | 1227 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| ChemExpress | +86-021-58950125 | info@chemexpress.com | China | 555 | 58 |
| Joyochem Co.,Ltd | +86-0531-82687558 +8613290333633 | sales@joyochem.com | China | 42 | 58 |
Related articles
- How to synthesize Tegoprazan?
- Tegoprazan is a novel orally active P-CAB. Key challenges in the drug preparation are the construction of the tetrasubstituted....
- Dec 25，2023
- What is Tegoprazan?
- Tegoprazan was approved by the Ministry of Food and Drug Safety (MFDS) for marketing in July 2018 for the treatment of gastroe....
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View Lastest Price from Tegoprazan manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-08 | Tegoprazan
942195-55-3
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. | |
 |
2024-04-07 | Tegoprazan
942195-55-3
|
US $100.00 / kg | 1kg | 99% | 1t | Zibo Wei Bin Import & Export Trade Co. Ltd. | |
 |
2023-06-19 | Tegoprazan
942195-55-3
|
US $0.00 / KG | 1KG | 98% | 1000KGS | Zhengzhou Anbu Chem Co.,Ltd |
-
- Tegoprazan
942195-55-3
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
-
- Tegoprazan
942195-55-3
- US $100.00 / kg
- 99%
- Zibo Wei Bin Import & Export Trade Co. Ltd.
-
- Tegoprazan
942195-55-3
- US $0.00 / KG
- 98%
- Zhengzhou Anbu Chem Co.,Ltd