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Glecaprevir

Approval
Glecaprevir
Glecaprevir structure
CAS No.
1365970-03-1
Chemical Name:
Glecaprevir
Synonyms
ABT-493;CS-2616;Glecaprevir;Glecaprevir INN;Glecaprevir API;Glecaprevir(ABT-493);ABT-493(Glecaprevir);ABT-493;ABT 493;ABT493;GLECAPREVIR;(1R,2R)-N-[[[(1R,2R)-2-[[4,4-Difluoro-4-(3-hydroxy-2-quinoxalinyl)-2-buten-1-yl]oxy]cyclopentyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-2-(difluoromethyl)-N-[(1-methylcyclopropyl)sulfonyl]cyclopropanecarboxamide cyclic (1→2)-ether;(33R,35S,91R,92R,5S,E)-5-(tert-butyl)-N-((1R,2R)-2-(difluoromethyl)-1-(((1-methylcyclopropyl)sulfonyl)carbamoyl)cyclopropyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-35
CBNumber:
CB83159912
Molecular Formula:
C38H46F4N6O9S
Formula Weight:
838.87
MOL File:
1365970-03-1.mol

Glecaprevir Properties

Density 
1.46±0.1 g/cm3(Predicted)
pka
4.46±0.40(Predicted)
FDA UNII
K6BUU8J72P

Glecaprevir price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27934 Glecaprevir 1365970-03-1 1mg $35 2021-12-16 Buy
Cayman Chemical 27934 Glecaprevir 1365970-03-1 25mg $613 2021-12-16 Buy
ChemScene CS-8098 Glecaprevir 99.93% 1365970-03-1 10mg $660 2021-12-16 Buy
ChemScene CS-8098 Glecaprevir 99.93% 1365970-03-1 25mg $1320 2021-12-16 Buy
ChemScene CS-8098 Glecaprevir 99.93% 1365970-03-1 50mg $2220 2021-12-16 Buy

Glecaprevir Chemical Properties,Uses,Production

Approval

On 19 December 2016, AbbVie submitted a new drug application to the U.S. Food and Drug Administration for the glecaprevir/pibrentasvir (trade name Mavyret) regimen for the treatment of all major genotypes of chronic hepatitis C. On 3 August 2017 the FDA approved the combination for hepatitis C treatment. In Europe, it was approved on 17 August 2017 for the same indication, under the trade name Maviret.

Uses

Glecaprevir (INN) is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that was identified jointly by AbbVie and Enanta Pharmaceuticals. It is being developed as a treatment of chronic hepatitis C infection in co-formulation with an HCV NS5A inhibitor pibrentasvir. Together they demonstrated potent antiviral activity against major HCV genotypes and high barriers to resistance in vitro.

Uses

Glecaprevir is an antiviral drug used in the treatment of patients with hepatitis C virus (HCV) genotype 1-6, of special interest for the treatment of patients with chronic kidney disease also suffering from HCV.

Application

Glecaprevir is an antiviral drug used in the treatment of patients with hepatitis C virus (HCV) genotype 1-6, of special interest for the treatment of patients with chronic kidney disease also suffering from HCV.

Side effects

The most common adverse effects, observed in at least 10% of phase 3 trial participants, were headache and fatigue.

Glecaprevir Preparation Products And Raw materials

Raw materials

Preparation Products


Glecaprevir Suppliers

Global( 69)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
TianYuan Pharmaceutical CO.,LTD
+86-755-23284190 13684996853
+86-755-23284190 sales@tianpharm.com CHINA 305 58
Huaian yishu technology co.,ltd
13852390259 86-0517-85883738
sales@yishuchem.com CHINA 53 58
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 9128 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26782 60
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19752 58
career henan chemical co
15093356674 0371-55982848
0086-371-86658258 factory@coreychem.com CHINA 29864 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
86-021-61999440
contact@trustwe.com CHINA 10008 58
Suzhou Ryan Pharmachem Technology Co.,Ltd.
0512-68780025-8002
0512-68780025-8004 yybi@ryanchem.com;sales@ryanchem.com CHINA 188 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19231 58
Career Henan Chemica Co
15093356674 0371-55982848
0371-86658258 laboratory@coreychem.com CHINA 30290 58

Related articles

  • Glecaprevir-Pibrentasvir (Mavyret)
  • MAVYRET is a prescription medicine used to treat adults and children 12 years of age and older or weighing at least 99 pounds ....
  • Dec 21,2021

View Lastest Price from Glecaprevir manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-01-03 Glecaprevir
1365970-03-1
US $1.00 / KG 1KG 99% 200kg Career Henan Chemical Co

1365970-03-1(Glecaprevir)Related Search:


  • Glecaprevir API
  • (1R,2R)-N-[[[(1R,2R)-2-[[4,4-Difluoro-4-(3-hydroxy-2-quinoxalinyl)-2-buten-1-yl]oxy]cyclopentyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-2-(difluoromethyl)-N-[(1-methylcyclopropyl)sulfonyl]cyclopropanecarboxamide cyclic (1→2)-ether
  • ABT-493(Glecaprevir)
  • CS-2616
  • ABT-493;ABT 493;ABT493;GLECAPREVIR
  • Glecaprevir
  • (33R,35S,91R,92R,5S,E)-5-(tert-butyl)-N-((1R,2R)-2-(difluoromethyl)-1-(((1-methylcyclopropyl)sulfonyl)carbamoyl)cyclopropyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-35
  • ABT-493
  • Glecaprevir(ABT-493)
  • Cyclopropanecarboxamide, N-[[[(1R,2R)-2-[[4,4-difluoro-4-(3-hydroxy-2-quinoxalinyl)-2-buten-1-yl]oxy]cyclopentyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-2-(difluoromethyl)-N-[(1-methylcyclopropyl)sulfonyl]-, cyclic (1→2)-ether, (1R,2R)-
  • Glecaprevir INN
  • 1365970-03-1
  • 1367970-03-1
  • C38H46F4N6O9S
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