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ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate

ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate structure

CAS No.: 118988-04-8

Chemical Name:: ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate

Synonyms: HO-PEG3-CH2COOEt;Hydroxy-PEG3-ethyl acetate;ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate;Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, ethyl ester;HO-PEG3-CH2COOEt/Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, ethyl ester

CBNumber:: CB83367469

Molecular Formula:: C10H20O6

Molecular Weight:: 236.26

MDL Number:: MFCD25956292

MOL File:: 118988-04-8.mol

Last updated:2023-02-23 14:24:01

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ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate Properties

Boiling point	332.3±27.0 °C(Predicted)
Density	1.105±0.06 g/cm3(Predicted)
pka	14.36±0.10(Predicted)

ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Acrotein	B-1228	HO-PEG3-CH2COOEt 97%	118988-04-8	1g	$412.5	2021-12-16	Buy

Product number	Packaging	Price	Buy
B-1228	1g	$412.5	Buy

ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate Chemical Properties,Uses,Production

Biological Activity

Hydroxy-PEG3-ethyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate Preparation Products And Raw materials

Raw materials

Preparation Products

HO-PEG3-CH2COOH

ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate Suppliers

Global( 11)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
Borenpharm Co., Ltd	027-65563561	sales@borenpharm.com	China	1246	55
Amatek Scientific Co. Ltd.	0512-56316828	info@amateksci.com	China	28822	58
Shanghai Tube Pharmaceutical Co., Ltd.	021-54338626 18017892860	sales@tubepharm.com	China	2221	58
Shanghai zhigan biotechnology co., LTD		zhiqianbio@126.com	China	19785	58
Shanghai Jiange Chemical Co., Ltd.	15921040873	1434142450@qq.com	CHINA	7651	58
Shaanxi borno biotechnology co., LTD	+86-13759708231	asherw9@hotmail.com	China	2351	58
Taizhou Nanfeng Pharmaceutical Research Institute	12345678910	nanfengdrug@163.com	China	15323	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223	psaitong@jm-bio.com	China	29834	58
LinkChem Co.,Ltd.	21-21-20222982 13124863828	sales@linkchem.cn	China	3000	58

Supplier	Advantage
Wuhan Borenpharm Co., Ltd	58
Borenpharm Co., Ltd	55
Amatek Scientific Co. Ltd.	58
Shanghai Tube Pharmaceutical Co., Ltd.	58
Shanghai zhigan biotechnology co., LTD	58
Shanghai Jiange Chemical Co., Ltd.	58
Shaanxi borno biotechnology co., LTD	58
Taizhou Nanfeng Pharmaceutical Research Institute	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
LinkChem Co.,Ltd.	58

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HO-PEG3-CH2COOEt ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate Hydroxy-PEG3-ethyl acetate HO-PEG3-CH2COOEt/Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, ethyl ester Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, ethyl ester 118988-04-8