EC 2.4.2.4
- CAS No.
- 9030-23-3
- Chemical Name:
- EC 2.4.2.4
- Synonyms
- TYMP;MNGIE;ECGF1;Gliostatin;EC 2.4.2.4;THYMIDINE PHOSPHORYLASE;Phosphorylase,thymidine;Thymidine Phosphorylase, recombinant;THYMIDINE PHOSPHORYLASE FROM*ESCHERICHIA COLI;ANTI-ECGF1 (CENTER) antibody produced in rabbit
- CBNumber:
- CB8341855
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00132426
- MOL File:
- Mol file
EC 2.4.2.4 price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | T2807 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥500?units/mL | 9030-23-3 | 500units | $156 | 2024-03-01 | Buy |
Sigma-Aldrich | T2807 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥500?units/mL | 9030-23-3 | 1000units | $201 | 2024-03-01 | Buy |
Sigma-Aldrich | T6632 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥900?units/mL, aseptically filled | 9030-23-3 | 5000units | $1600 | 2024-03-01 | Buy |
Sigma-Aldrich | T2807 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥500?units/mL | 9030-23-3 | 5000units | $411.6 | 2024-03-01 | Buy |
Sigma-Aldrich | SRE0006 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, Suitable for manufacturing of diagnostic kits and reagents, buffered aqueous solution, ≥500?units/mL | 9030-23-3 | 5000units | $300 | 2024-03-01 | Buy |
EC 2.4.2.4 Chemical Properties,Uses,Production
Uses
Thymidine phosphorylase has been used in a study to assess TAS-102 treatment in patients with advanced solid tumors. Thymidine phosphorylase has also been used in a study to investigate antitumor effects of the FP3 protein on patient-derived tumor tissue xenograft models of primary colon carcinoma.
Uses
Thymidine phosphorylase has been used in a study to evaluate biomarkers for advanced breast cancer patients treated with capecitabine-based first-line chemotherapy. Thymidine phosphorylase has also been used in a study to investigate implications for the clinical efficacy of nucleoside analogues.
General Description
Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation.
Biochem/physiol Actions
An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays.
EC 2.4.2.4 Preparation Products And Raw materials
Raw materials
Preparation Products
EC 2.4.2.4 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40068 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4698 | 58 |
Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9966 | 58 |
Shanghai Guchen Biotechnology Co., LTD | 021-34675735 19147740836 | 1986399151@qq.com | China | 9849 | 58 |
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