Cyclopropanecarboxylic acid
- CAS No.
- 1759-53-1
- Chemical Name:
- Cyclopropanecarboxylic acid
- Synonyms
- Cyclopropionic acid;cyclopropanecarboxylic;CYCLOPROPYL CARBOXYLIC ACID;CPC-ACID;Cyclopropane c;Cyclopropanic acid;Carboxycyclopropane;RARECHEM AL BO 0005;Ring propyl forMate;Olapali impurity 20
- CBNumber:
- CB8343293
- Molecular Formula:
- C4H6O2
- Molecular Weight:
- 86.09
- MDL Number:
- MFCD00001287
- MOL File:
- 1759-53-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Cyclopropanecarboxylic acid 95% | C116602 | 25g | $48.7 |
| Cyclopropanecarboxylic acid 95% | C116602 | 100g | $63.84 |
| Cyclopropanecarboxylic Acid >98.0%(GC)(T) | C0387 | 25mL | $25 |
| Cyclopropanecarboxylic Acid >98.0%(GC)(T) | C0387 | 100mL | $67 |
| Cyclopropanecarboxylic Acid >98.0%(GC)(T) | C0387 | 500mL | $234 |
| More product size | |||
| Melting point | 14-17 °C (lit.) |
|---|---|
| Boiling point | 182-184 °C (lit.) |
| Density | 1.081 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 161 °F |
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform, Ethyl Acetate |
| form | Liquid |
| pka | 4.83(at 25℃) |
| color | Clear colorless to light yellow |
| PH | 3 (10g/l, H2O, 22℃) |
| BRN | 969839 |
| InChI | 1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) |
| InChIKey | YMGUBTXCNDTFJI-UHFFFAOYSA-N |
| SMILES | OC(=O)C1CC1 |
| LogP | 0.630 |
| CAS DataBase Reference | 1759-53-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 008803351S |
| NIST Chemistry Reference | Cyclopropanecarboxylic acid(1759-53-1) |
| EPA Substance Registry System | Cyclopropanecarboxylic acid (1759-53-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 34-22 | |||||||||
| Safety Statements | 26-36/37/39-45-27 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GZ1100000 | |||||||||
| Hazard Note | Irritant/Corrosive | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29162000 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,172mg/kg (172mg/kg),Journal of Pharmacy and Pharmacology. Vol. 21, Pg. 85, 1969. | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
Cyclopropanecarboxylic acid price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C116602 | Cyclopropanecarboxylic acid 95% | 1759-53-1 | 25g | $48.7 | 2025-07-31 | Buy |
| Sigma-Aldrich | C116602 | Cyclopropanecarboxylic acid 95% | 1759-53-1 | 100g | $63.84 | 2025-07-31 | Buy |
| TCI Chemical | C0387 | Cyclopropanecarboxylic Acid >98.0%(GC)(T) | 1759-53-1 | 25mL | $25 | 2025-07-31 | Buy |
| TCI Chemical | C0387 | Cyclopropanecarboxylic Acid >98.0%(GC)(T) | 1759-53-1 | 100mL | $67 | 2025-07-31 | Buy |
| TCI Chemical | C0387 | Cyclopropanecarboxylic Acid >98.0%(GC)(T) | 1759-53-1 | 500mL | $234 | 2025-07-31 | Buy |
Cyclopropanecarboxylic acid Chemical Properties,Uses,Production
Description
Cyclopropanecarboxylic acid (1759-53-1) is a kind of organic acid. It is a clear liquid used as an intermediate for agrochemicals, pharmaceuticals, and other organic synthesis for the applications of electronics, chemicals, polymer additives, coatings, adhesives, surfactants, and other applications1. Moreover, its derivatives of are used against parasites in plants and animals. For example, the alkynyl esters of cyclopropane-carboxylic acid are used as pesticides. Similarly, cyclopropane carboxylic acid esters containing a polyhalogenated substituent are used as fungicides. The ethyl derivative is reagent used in the addition of cyclopropane and can act as annulation reagent for the conversion of aromatics to 2-methylindanones under Friedel-Crafts conditions2.
Uses
Cyclopropanecarboxylic acid (1759-53-1) is a monocarboxylic acid and a member of cyclopropanes. It is a conjugate acid of a cyclopropanecarboxylate.
Chemical Properties
clear colourless to light yellow liquid
Uses
Cyclopropanecarboxylic Acid is used as a reagent in the synthesis of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. Also used as a reagent in the synthesis of 2-alkyloxazoles as potent and selective PI4KIIIb inhibitors demonstrating inhibition of HCV replication.
Definition
ChEBI: Cyclopropanecarboxylic acid is a monocarboxylic acid and a member of cyclopropanes. It is a conjugate acid of a cyclopropanecarboxylate.
Preparation
Cyclopropanecarboxylic acid has been prepared by the hydrolysis of cyclopropyl cyanide, although it is unnecessary to isolate the nitrile; by heating cyclopropanedicarboxylic acid; and by the action of alkali on ethyl γ-chlorobutyrate.7 The last two methods do not appear to be of practical importance. The oxidation of cyclopropyl methyl ketone with sodium hypobromite is reported to be an excellent preparative method for this acid.
Org. Synth. 1944, 24, 36
DOI: 10.15227/orgsyn.024.0036
Biological Functions
Cyclopropanecarboxylic acid has a hypoglycemic effect.
Toxicity evaluation
Cyclopropanecarboxylic acid is a flammable liquid, which is orally toxic and classified as a Category 4 acute oral toxicity. It exhibits moderate toxicity upon skin contact, with severe exposure potentially causing skin burns and eye damage.
Cyclopropanecarboxylic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Zhejiang Karry Pharmachem Co., Ltd. | +8613567161161 | info@karrypharma.com | China | 34 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8753 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13799 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21597 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
Related articles
- Cyclopropanecarboxylic Acid: Solubility, Microwave Spectrum, Metabolism, and Ester Prodrugs
- Cyclopropanecarboxylic acid has polar-solvent solubility, its gas-phase structure is studied via microwave spectrum, is metabo....
- Sep 12，2025
View Lastest Price from Cyclopropanecarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-10 | Cyclopropanecarboxylic acid
1759-53-1
|
US $0.00 / KG | 1KG | 97% | 500kgs/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-01-30 | Cyclopropanecarboxylic acid
1759-53-1
|
US $1.00 / kg | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-11-20 | Cyclopropanecarboxylic acid
1759-53-1
|
US $0.00-0.00 / kg | 1kg | 98% | 100tons | Shandong Vital Biotechnology Co., Ltd. |
-
- Cyclopropanecarboxylic acid
1759-53-1
- US $0.00 / KG
- 97%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Cyclopropanecarboxylic acid
1759-53-1
- US $1.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Cyclopropanecarboxylic acid
1759-53-1
- US $0.00-0.00 / kg
- 98%
- Shandong Vital Biotechnology Co., Ltd.
