LEUKEMIA INHIBITORY FACTOR, MOUSE
- CAS No.
- Chemical Name:
- LEUKEMIA INHIBITORY FACTOR, MOUSE
- Synonyms
- LIF;ESGRO;MOUSE LIF;LIF, MOUSE;LEUKEMIA INHIBITORY FACTOR;LEUKEMIA INHIBITORY FACTOR MURINE;LEUKEMIA INHIBITORY FACTOR, MOUSE;Recombinant Mouse Lif Protein, No Tag;Leukemia Inhibitory Factor from mouse
- CBNumber:
- CB8349624
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00283681
- MOL File:
- Mol file
LEUKEMIA INHIBITORY FACTOR, MOUSE price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | LIF2010 | Leukemia Inhibitory Factor from mouse 10 μg, mouse recombinant LIF protein, expressed in E. coli, suitable for stem cell culture | 10μg | $384 | 2024-03-01 | Buy | |
Sigma-Aldrich | LIF2005 | Leukemia Inhibitory Factor from mouse 5 μg, mouse recombinant LIF protein, expressed in E. coli, suitable for stem cell culture | 5μg | $257 | 2024-03-01 | Buy | |
Sigma-Aldrich | L5158 | Leukemia Inhibitory Factor from mouse LIF, recombinant, expressed in E. coli, 10 μg/ml, buffered aqueous solution, suitable for cell culture | 5μg | $325 | 2024-03-01 | Buy | |
Sigma-Aldrich | L5158 | Leukemia Inhibitory Factor from mouse LIF, recombinant, expressed in E. coli, 10 μg/ml, buffered aqueous solution, suitable for cell culture | 10μg | $398 | 2024-03-01 | Buy | |
Usbiological | 357047 | LIF | 48Tests | $588 | 2021-12-16 | Buy |
LEUKEMIA INHIBITORY FACTOR, MOUSE Chemical Properties,Uses,Production
Uses
Leukemia Inhibitory Factor from mouse has been used:
- as a component of enriched co-culture media
- as a supplement in Dulbecco′s modified eagle′s medium (DMEM)/F12 medium for culturing heart cells
- as a component in maintenance medium for maintaining embryonic stem cells
- to treat ovaries in ovarian culture
Biochem/physiol Actions
Leukemia Inhibitory Factor (LIF) is a pleiotropic glycoprotein originally described to inhibit the proliferation of the murine myeloid leukemic cell line M1, while inducing differentiation into macrophages. Other activities were later identified to LIF, which is known by a variety of synonyms, including DIF, D-factor, DIA, DRF, CNDF, HILDA, HSF-III, and MLPLI. Human LIF exerts its actions through a receptor comprising a 190 kDa LIF-binding α-chain (130 kDa, mouse) and a 130 kDa signal-transducing β-chain (gp130), which is shared with CNTF, OSM, L-6 and IL-11. As such, it is a member of the gp130 family of the cytokine receptor superfamily. LIF receptors have been identified on several cells, including monocytes, liver, placenta and embryonic stem cells. Natural LIF is heavily glycosylated, showing an apparent molecular weight of 32 kDa to 62 kDa, depending on the source, but absence of glycosylation appears not to affect its biological activity. A single gene encodes LIF, which is secreted as a single chain glycoprotein containing 180 amino acids for human or mouse with a conserved disulfide bond. Human and mouse LIF share 78% sequence homology. Human LIF can activate mouse cells, but mouse LIF cannot activate human cells.
LEUKEMIA INHIBITORY FACTOR, MOUSE Preparation Products And Raw materials
Raw materials
Preparation Products
LEUKEMIA INHIBITORY FACTOR, MOUSE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
HANSHANG CHEMICAL SCIENTIFIC LIMITED | 021-50521775 15800962688 | sales@hanshangchem.com | China | 471 | 57 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Wuhan Chemstan Biotechnology Co., Ltd. | 15926423062 | 422450190@qq.com | China | 10132 | 58 |
Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 6633 | 58 |
Shanghai Yingxin Laboratory Equipment Co., Ltd. | 021-021-59178156 17002132182 | 3146474380@qq.com | China | 11303 | 58 |
Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
ACROBiosystems | 18514007688 | jiaxin.zhao@acrobiosystems.com | China | 453 | 58 |