Diallyl sulfide | 592-88-1

Diallyl sulfide Properties

Melting point	-83 °C
Boiling point	138 °C(lit.)
Density	0.887 g/mL at 25 °C(lit.)
vapor density	3.9 (vs air)
vapor pressure	7 mm Hg ( 20 °C)
FEMA	2042 \| ALLYL SULFIDE
refractive index	n20/D 1.490(lit.)
Flash point	115 °F
storage temp.	2-8°C
solubility	3mg/mL in ethanol;5mg/mL in DMSO;10mg/mL in dimethyl formamide
form	Liquid
color	Clear colorless
Odor	at 0.10 % in propylene glycol. sulfurous onion garlic horseradish metallic
Odor Type	sulfurous
Odor Threshold	0.00022ppm
explosive limit	1.1%(V)
Water Solubility	Soluble in alcohol, chloroform, ether, and carbon tetrachloride. Insoluble in water.
Merck	14,297
JECFA Number	458
BRN	1736016
Dielectric constant	4.9（20℃）
InChIKey	UBJVUCKUDDKUJF-UHFFFAOYSA-N
LogP	2.61
Substances Added to Food (formerly EAFUS)	ALLYL SULFIDE
FDA 21 CFR	172.515
CAS DataBase Reference	592-88-1(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	60G7CF7CWZ
NIST Chemistry Reference	1-Propene, 3,3'-thiobis-(592-88-1)
EPA Substance Registry System	1-Propene, 3,3'-thiobis- (592-88-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02

Signal word

Warning

Hazard statements

H226

Precautionary statements

Hazard Codes

Risk Statements

Safety Statements

RIDADR

UN 1993 3/PG 3

WGK Germany

2

RTECS

BC4900000

TSCA

Yes

HazardClass

3

PackingGroup

III

HS Code

29309070

NFPA 704

	2
2		0

Diallyl sulfide price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	W204218	Allyl sulfide ≥97%, FG	592-88-1	100g	$70.1	2024-03-01	Buy
Sigma-Aldrich	W204218	Allyl sulfide ≥97%, FG	592-88-1	1kg	$429	2024-03-01	Buy
Sigma-Aldrich	W204218	Allyl sulfide ≥97%, FG	592-88-1	4kg	$1310	2024-03-01	Buy
Sigma-Aldrich	40647	Allyl sulfide analytical standard	592-88-1	1ml	$63.9	2022-05-15	Buy
Sigma-Aldrich	40647	Allyl sulfide analytical standard	592-88-1	5ml	$259	2022-05-15	Buy

Product number	Packaging	Price	Buy
W204218	100g	$70.1	Buy
W204218	1kg	$429	Buy
W204218	4kg	$1310	Buy
40647	1ml	$63.9	Buy
40647	5ml	$259	Buy

Diallyl sulfide Chemical Properties,Uses,Production

General Description

Diallyl sulfide refers to the following 4 ingredients: diallyl monosulfide, diallyl disulfide, diallyl trisulfide and diallyl tetrasulfide, which exist in putrefaction decomposer of vegetables, green onion and the fruit of.cruciferous plants. As the main component of garlic extract, it is featured with strong anti-cancer, anti-virus, antibacterial activity, strong inhibition of platelet aggregation and immunity improvement. It has been widely used in the industries such as medical and health, fodder and the like.

Physical & Chemical Properties

It is an oily substance scented with garlic. Boiling point: 139 ° C (101.056Pa), relative density: 0.8876, refractive index: 1.4877. Soluble in organic solvents such as ether and the like, insoluble in water. Also it can be oxidized to diallyl sulfone.

Figure 1: Diallyl Disulfide

Figure 2: Diallyl trisulfide

Preparation Method

The two main methods for preparation of diallyl sulfide are: biological extraction and chemical synthesis.

Biological extraction

The more common biological extraction methods are steam distillation, organic solvent extraction and supercritical CO2 extraction. Steam distillation is to use water as a solvent, then heat under a certain pressure to extract the soluble active ingredients from the natural products. The advantage of this method is that it is simple to operate and suitable for the extraction of active ingredients that are generally easier to extract. Its disadvantages include the greater loss of the active ingredients in the thermosensitives, lower yield, and that the active ingredients in the extract are not easily separated.
Process for allicin extraction: fermentation temperature: 50 ~ 55 ℃, fermentation duration: 2h ~ 3h, add water into the garlic with the proportion of 1: 4 water, distilled for the duration of 1.5h ~ 2h.
Organic solvent extraction method is to use organic solvent as extraction agent, and extract the active ingredients of natural products at a certain temperature and extraction duration. Usually methanol, ethanol, acetone, ethyl ether or the mixture of these solvents are used as the organic solvents. Compared withthe steam distillation extraction, the advantage of the organic solvent extraction is that the extract has higher purity. Also it is one of the traditional extraction methods.
Use ethanol with volume fraction of 95% as the extraction solvent, and add the extractant in proportion of 1g: 4mL. First the enzymolysis time was 0.5h when the temperature is set to 40 ℃; then have the extraction for 1.5h when the temperature is set to 30 ℃; finally set the temperature at 50 ℃, and have it concentrated under reduced pressure in a steamer rotating at a speed of 4500r / min to extract allicin. The extraction rate can reach 0.24%.

Chemical synthesis

Mix Na2S2O3•5H2O62g (0.25mol) and 3-bromopropene 24g (0.20mol) in ethanol - water (V ethanol: V water = 60:40) evenly and reflux to homogeneity. Add 30mL of concentrated hydrochloric acid, reflux for 5h, standing still, then separate the upper layer and put it into 100mL10% NaOH solution placed in an ice bath, add 80mL of 25% K3Fe (CN) 6 (6mmol) aqueous solution while stirring and stop after 2.5h. Separate the organic layer and dry it over anhydrous sodium sulfate. Then filter off the desiccant, recover the solvent, and finally 6.6 g of pale yellow oily substance will be obtained.

Figure 3： Synthetic route

Uses

Used as a reagent.
Used in the industries such as medical and health, fodder and the like.

Toxicity

GRAS(FEMA)。

Maximum limits

FEMA (mg / kg): Drinks 0.04; Cold Drink 0.06; Confectionery 0.07; Bakery Products 0.05; Seasoning 13; Meat 3.7.
FDA, § 172.515: Appropriate amount.

Chemical Properties

A colorless liquid with characteristic garlic odor. Oil-soluble component of garlic

Chemical Properties

clear colorless liquid

Occurrence

Reported found in garlic (Allium sativum L.), onion (Allium cepa L.), nira (Allium tuberosum Rottl.), caucas (Allium victoralis L.), mustard (Brassica species) and cooked/boiled beef

Uses

antibacterial, antifungal, antineoplastic, antihypercholesterolaemic, hepatoprotectant

Uses

manufacture of flavors.

Uses

Diallyl sulfide is a modulator of drug metabolizing enzyme P450 system and inducer of the phase II detoxifying enzyme GST. Diallyl sulfide is also an inhibitor of CYP2E1 and believed to prevent chemically-induced carcinogenesis in many tissues. It is also used as a food additive. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Definition

ChEBI: Diallyl sulfide is an organic sulfide.

Preparation

From allyl iodide plus potassium sulfide in alcoho

Aroma threshold values

Detection at 0.05 ppb

Taste threshold values

Taste characteristics at 2 ppm: sulfureous, onion–garlic and vegetative radish-like with a slightly hot nuance

General Description

Allyl sulfide is a volatile flavor compound naturally found in Allium species such as garlic and onion. It is has a characteristic garlic odor and is used as a flavoring agent in meat and condiments.

Biochem/physiol Actions

Organosulfur compound from garlic that inhibits chemically-induced carcinogenesis in experimental animals. Competitive inhibitor of Cytochrome P450 2E1 (CYP2E1) that, in turn, blocks the activation of several chemcal carcinogens.

Anticancer Research

It is a thioether, found in garlic, inhibits cytochrome P450 IIE1 isoform, and therebysuppresses carcinogenesis (Aggarwal and Shishodia 2004). The consumption ofgarlic provides protection from gastrointestinal cancers and also suppresses theprogression of colorectal adenomas (Hosseini and Ghorbani 2015).

Diallyl sulfide synthesis

Synthesis of Diallyl sulfide from DIALLYLSULFONE

Diallyl sulfide Preparation Products And Raw materials

Raw materials

Garlic P.E Sodium sulfide nonahydrate CAPSAICIN/CAPSICUM Sodium sulfide

Preparation Products

clopenthixol 2-METHYL-PENT-4-ENAL 1,3-Dimercaptopropane Diallyldisulfide

Diallyl sulfide Suppliers

Global( 209)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9352	55
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5909	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 15319487004	1015@dideu.com	China	2263	58

Supplier	Advantage
career henan chemical co	58
Hebei Mojin Biotechnology Co., Ltd	58
Hangzhou FandaChem Co.,Ltd.	55
Hubei Jusheng Technology Co.,Ltd.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58

View Lastest Price from Diallyl sulfide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-24	Diallyl sulfide 592-88-1	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-02-13	Allyl Sulfide 592-88-1	US $80.00 / kg	1kg	99%	100MT	Hebei baicao biology science and technology co., ltd
2021-08-31	Allyl Sulfide 592-88-1	US $50.00 / KG	1Kg/Bag	99.99%	20 tons/month	Wuhan Monad Medicine Tech Co.,LTD

Diallyl sulfide
592-88-1
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

Allyl Sulfide
592-88-1
US $80.00 / kg
99%
Hebei baicao biology science and technology co., ltd

Allyl Sulfide
592-88-1
US $50.00 / KG
99.99%
Wuhan Monad Medicine Tech Co.,LTD

Diallyl sulfide Spectrum

Diallyl sulfide(592-88-1)MS Diallyl sulfide(592-88-1)¹HNMR Diallyl sulfide(592-88-1)¹³CNMR Diallyl sulfide(592-88-1)IR1 Diallyl sulfide(592-88-1)Raman

592-88-1(Diallyl sulfide)Related Search:

Diallylamine Allyl ether Diallyl trisulfide Allyl mercaptan 1,5-HEXADIENE

Allyl chloride 2,2'-Thiobisethylamine Dimethyl sulfide Allyl glycidyl ether Sodium sulfide

CARBONYL SULFIDE Sodium allylsulfonate Diphenyl sulfide Borane-methyl sulfide complex Allyl bromide

Hydrogen Sulfide Allicin Diallyldisulfide, remainder mainly diallyl sulfide,Diallyldisulfide, 70%, remainder mainly diallyl sulfide

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(CH2=CHCH2)2S 1-propene,3,3’-thiobis- 3-(Allylsulfanyl)-1-propene 3,3’-thiobis-1-propen 3,3’-thiobis-1-Propene 3-Prop-2-enylsulfanylprop-1-ene Bis(2-propenyl) sulfide 3-(2-Propenylthio)propan-1-ene Di(2-propen-1-yl) sulfide 3,3-Thiobis(1-propene) ALLYLMONOSULPHIDE Allyl sulfide, 97% 25ML ALLYL SULFIDE(SH) Allyl sulfide,Diallyl sulfide DIALLYSULFIDE allyl thioether ALLYL SULFIDE 97+% DIALLYLMONOSULPHIDE diallylsulfane NSC 20947 Allyl sulfide 97% DIALLYL SULFIDE Diallyl thioether allylmonosulfide Diallyl monosulfide Diallyl thioather diallylmonosulfide oilgarlic THIOALLYL ETHER Diallyl sulfide for synthesis 2-PROPENYL SULPHIDE Allyl Sulfide > Diallyl sulfide USP/EP/BP Allyl monosulfide Diallyl sulfide, 97% / Allyl sulfide DIALLYL SULPHIDE FEMA 2042 di-2-propenyl sulfide Oil garlic ALLYL SULFIDE ALLYL SULPHIDE Allyl sulfur 592-88-1 CH2CHCH2SCH2CHCH2 C6H10S Sulfides/Disulfides Sulfur Compounds Organic Building Blocks Building Blocks sulfide Flavor Allium cepa (Onion) Allium sativum (Garlic) Armoracia rusticana (Horseradish) Building Blocks Chemical Synthesis Nutrition Research Organic Building Blocks Phytochemicals by Plant (Food/Spice/Herb)