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NS 1619

CAS No.
153587-01-0
Chemical Name:
NS 1619
Synonyms
NS 161;NS 1619;NS1619;NS 1619;NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN;1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b;1-(2-Hydroxy-5-(Trifluoromethyl)Phenyl)-5-(Trifluoromethyl)-1H-Benzo[D]Imidazol-2-Ol;1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one;1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE;1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-
CBNumber:
CB8359809
Molecular Formula:
C15H8F6N2O2
Molecular Weight:
362.23
MDL Number:
MFCD00928190
MOL File:
153587-01-0.mol
Last updated:2023-06-30 15:45:59

NS 1619 Properties

Density 1.563±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL
pka 8.32±0.48(Predicted)
form solid
color white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3

NS 1619 price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N170 NS 1619 powder 153587-01-0 5mg $180 2024-03-01 Buy
Sigma-Aldrich N170 NS 1619 powder 153587-01-0 25mg $645 2024-03-01 Buy
Cayman Chemical 18876 NS 1619 ≥98% 153587-01-0 1mg $37 2024-03-01 Buy
Cayman Chemical 18876 NS 1619 ≥98% 153587-01-0 5mg $81 2024-03-01 Buy
Cayman Chemical 18876 NS 1619 ≥98% 153587-01-0 10mg $142 2024-03-01 Buy
Product number Packaging Price Buy
N170 5mg $180 Buy
N170 25mg $645 Buy
18876 1mg $37 Buy
18876 5mg $81 Buy
18876 10mg $142 Buy

NS 1619 Chemical Properties,Uses,Production

Uses

NS 1619 is a large conductance calcium-activated potassium channels (BKCa) activator and has been shown to induce precondition in the heart.

Definition

ChEBI: A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It i an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).

Biochem/physiol Actions

NS 1619 is a selective large conductance Ca2+-activated K+-channel activator. The compound is known for its vasodilating and anti-proliferative properties. It is studied that NS 1619 can protect cardiac muscle against ischemia and reperfusion injury.

storage

+4°C

NS 1619 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 96)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29827 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
RR Scientific LLC
+86-13917743231 sales@rrscientific.com United States 878 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 132020 58

View Lastest Price from NS 1619 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NS 1619 pictures 2020-01-14 NS 1619
153587-01-0
US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co
  • NS 1619 pictures
  • NS 1619
    153587-01-0
  • US $9.80 / KG
  • ≥99%
  • Career Henan Chemical Co

NS 1619 Spectrum

NS 1619 NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN 1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE 1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one 1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b NS1619;NS 1619 NS 161 2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)- 1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one 1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one 1-(2-Hydroxy-5-(Trifluoromethyl)Phenyl)-5-(Trifluoromethyl)-1H-Benzo[D]Imidazol-2-Ol 153587-01-0 C15H8F6N2O2 Monovalent Ion Channels Ion Channels Voltage-gated Ion Channels Potassium Channel Modulators Cell Signaling and Neuroscience Cell Biology BioChemical API