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Anticholinesterase

CAS No.
9000-81-1
Chemical Name:
Anticholinesterase
Synonyms
ACHE;ACETYLCHOLINESTERASE;Native Electrophorus electricus (electric eel) Acetylcholinesterase;AcCholE;EC 3.1.1.7;Cholinesterase I;ANTICHOLINESTERASE;TRUE CHOLINESTERASE;Acetylcholinesterases;ACETYLCHOLINE ESTERASE
CBNumber:
CB8359935
Molecular Formula:
NULL
Molecular Weight:
0
MDL Number:
MFCD00081268
MOL File:
Mol file
Last updated:2023-05-04 15:14:11

Anticholinesterase Properties

storage temp. -20°C
solubility H2O: 1 mg/mL
form powder
color slightly yellow
FDA UNII ACETYLCHOLINESTERASE ELECTROPHORUS ELECTRICUS (83KH8K2107)
ACETYLCHOLINESTERASE HUMAN (EK71H4HC3N)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P285-P304+P341-P342+P311-P501
Hazard Codes  B
WGK Germany  3
10-21
Toxicity The inhibition of AChE by these anticholinesterases leads to an accumulation of endogenous ACh, and thus results in hyperactivation of cholinergic receptors. Signs of acute poisoning can include irritability, tremors, convulsions, and predominately parasympathetic effects, with death usually the result of respiratory failure. Since AChE is contained in erythrocytes, the assay of erythrocyte AChE activity can be used as a diagnostic tool to assess exposure to organophosphorus anticholinesterases.

Anticholinesterase price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C3389 Acetylcholinesterase from Electrophorus electricus (electric eel) Type VI-S, lyophilized powder, 200-1,000?units/mg protein 9000-81-1 500units $95 2024-03-01 Buy
Sigma-Aldrich C3389 Acetylcholinesterase from Electrophorus electricus (electric eel) Type VI-S, lyophilized powder, 200-1,000?units/mg protein 9000-81-1 2000units $252 2024-03-01 Buy
Sigma-Aldrich C3389 Acetylcholinesterase from Electrophorus electricus (electric eel) Type VI-S, lyophilized powder, 200-1,000?units/mg protein 9000-81-1 10000units $862 2024-03-01 Buy
Sigma-Aldrich C2888 Acetylcholinesterase from Electrophorus electricus (electric eel) Type V-S, lyophilized powder, ≥1,000?units/mg protein 9000-81-1 500units $133 2024-03-01 Buy
Sigma-Aldrich C2888 Acetylcholinesterase from Electrophorus electricus (electric eel) Type V-S, lyophilized powder, ≥1,000?units/mg protein 9000-81-1 1000units $268 2024-03-01 Buy
Product number Packaging Price Buy
C3389 500units $95 Buy
C3389 2000units $252 Buy
C3389 10000units $862 Buy
C2888 500units $133 Buy
C2888 1000units $268 Buy

Anticholinesterase Chemical Properties,Uses,Production

Uses

Pesticides.

Uses

Acetylcholinesterase from Electrophorus electricus (electric eel) has been used:

  • in acetylcholinesterase activity assay
  • to study its effects on Xenopus embryonic hippocampal cells
  • to study the effect of acetylcholine inhibitors on development and plasticity

Uses

Acetylcholinesterase (AChE) from Sigma has been used in the structure-activity study of phosphoramido acid esters as inhibitors of AChE.

Definition

Any substance that inhibits or inactivates acetylcholinesterase, thereby preventing the hydrolysis of acetylcholine. Their action leads to an accumulation of endogenous acetylcholine with a resultant hyperactivity of cholinergic neurons, which can prove lethal.

General Description

Predominantly exists as a tetrameric glycoprotein composed of disulfide-linked homodimers with a monomer MW of ~80 kDa.

Hazard

Tremors; convulsions; respiratory failure; death.

Biochem/physiol Actions

Acetylcholinesterase (AChE) is regarded as a biomarker in neurotoxicity. It is a modulator of nitric oxide signal transduction pathway and marker of membrane integrity and aging. The levels of erythrocyte (RBC) AChE are affected on pesticide exposure and in hemolytic anemia. RBC AChE is a marker in Hirschsprung′s disease and inflammation.

Anticholinesterase Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 137)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
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career henan chemical co
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Creative Enzymes
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Hefei TNJ Chemical Industry Co.,Ltd.
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ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
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+86-27-59207850 +86-13986145403 info@fortunachem.com China 5981 58
Baoji Guokang Healthchem co.,ltd
+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9427 58

View Lastest Price from Anticholinesterase manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Anticholinesterase pictures 2021-09-29 Anticholinesterase
9000-81-1
US $0.00-0.00 / g 1g 98.0% 1kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Anticholinesterase pictures 2019-07-06 Anticholinesterase
9000-81-1
US $1.00 / kg 1kg 95%-99% 100kg Career Henan Chemical Co
Esterase, acetyl choline TRUE CHOLINESTERASE TRUE CHOLINESTERASE HUMAN TRUE CHOLINESTERASE TYPE VI-S TRUE CHOLINESTERASE TYPE V-S TRUE CHOLINESTERASE TYPE XII-S ACETYLCHOLINESTERASE TYPE III ELECTRIC ACETYLCHOLINE ESTERASE F. ELECTROPHORUS ELECT., ~850 U/MG CHOLINESTERASE, ACETYL AMPHIPHILIC FROM HUMAN ERYTH CHOLINESTERASE ACETYL TYPE XIIIFROM HUMA N ERYTHROC ACETYLCHOLINE ESTERASE MEMBR.B. F. BOV. ERYTHROC. ~400U/MG* Acetylcholinesterase from electric eel ACETYLCHOLINE ESTERASE ACETYLCHOLINE ACETYLHYDROLASE ACETYLCHOLINE ACETYLHYDROLASE HUMAN ACETYLCHOLINE ACETYLHYDROLASE TYPE VI-S ACETYLCHOLINE ACETYLHYDROLASE TYPE V-S ACETYLCHOLINE ACETYLHYDROLASE TYPE XII-S EC 3.1.1.7 CHOLINESTERASE, ACETYL CHOLINESTERASE, ACETYL HUMAN CHOLINESTERASE, ACETYL TYPE VI-S CHOLINESTERASE, ACETYL TYPE V-S CHOLINESTERASE, ACETYL TYPE XII-S ANTICHOLINESTERASE CHOLINESTERASE, ACETYL TYPE VI-S FROMELE CTRIC EEL ACETYLCHOLINESTERASE TYPE XII-S BOVINE CHOLINESTERASE, ACETYL TYPE V-SFROM ELEC TRIC EEL CHOLINESTERASE, ACETYL HUMANRECOMBINANT ACETYLCHOLINE ESTERASE F. ELECTROPHORUS& AcetylcholinesteraseExBovineErythro- Cholinesterase,BeefPancreas Acetylcholinesterasefrombovineerythrocytes acetylcholinesterase from electrophorus electricus (electric eel) acetylcholinesterase from human erythrocytes acetylcholinesterase human ACETYL CHOLINESTERASE TYPE V-S FROM ELECTRIC EEL Acetylcholine acetylhydrolase, AChE, Cholinesterase, Acetyl Acetylcholine acetylhydrolase, AChE Acetylcholinesterase-Agarose Acetylcholine acetylhydrolase, AChE, Acetylcholine Esterase, membrane-bound, from bovine erythrocytes Acetylcholinesterase human,AChE, Acetylcholine acetylhydrolase Acetylcholinesterase from human erythrocytes,AChE, Acetylcholine acetylhydrolase CHOLINESTERASE ACETYL TYPE III Acetylcholinesterase from Electrophorus electricus (electric eel),AChE, Acetylcholine acetylhydrolase, Cholinesterase, Acetyl Acetylcholine esterase from bovine erythrocytes, lyophil. Esterase, acetylcholine (ELECTRIC EEL) ACETYLCHOLINESTERASE FROM ELECTRO Cholinesterase I Acetylthiocholinesterase Acetylcholinesterases Acetylcholinesterase (AChE) Acetylcholine hydrolase Acetyl beta-methylcholinesterase AcCholE Acetylcholinesterase from electric eel, 200u/g Acetylcholinesterase, 200u/g Native Human erythrocytes Acetylcholinesterase