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Uses and Synthetic Methods of Amygdalin Category Toxicity classification Acute toxicity Flammability Hazardous properties Storage and transportation Fire extinguishing agent
Amygdalin structure
Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

Amygdalin Properties

Melting point:
223-226 °C(lit.)
-38.5 º (c=4, H2O)
Boiling point:
563.27°C (rough estimate)
1.4474 (rough estimate)
refractive index 
-40 ° (C=2, H2O)
storage temp. 
H2O: 0.1 g/mL hot, clear to very faintly turbid, colorless
White to Off-white
optical activity
[α]20/D 39±2°, c = 2% in H2O
Water Solubility 
83 g/L (25 ºC)
CAS DataBase Reference
29883-15-6(CAS DataBase Reference)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22
Safety Statements  26-36/37/39-45-24/25
RIDADR  2811
WGK Germany  3
RTECS  OO8450000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29389090
Hazardous Substances Data 29883-15-6(Hazardous Substances Data)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P501 Dispose of contents/container to..…

Amygdalin price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 10050 Amygdalin BioXtra, ≥97.0% (HPLC) 29883-15-6 5g $81.3 2018-11-13 Buy
Sigma-Aldrich 10050 Amygdalin BioXtra, ≥97.0% (HPLC) 29883-15-6 25g $311 2018-11-13 Buy
TCI Chemical A0443 Amygdalin >97.0%(HPLC) 29883-15-6 1g $22 2018-11-22 Buy
TCI Chemical A0443 Amygdalin >97.0%(HPLC) 29883-15-6 10g $123 2018-11-22 Buy
Alfa Aesar J61472 D-Amygdalin, 98% 29883-15-6 1g $27.7 2018-11-13 Buy

Amygdalin Chemical Properties,Uses,Production

Uses and Synthetic Methods of Amygdalin

Amygdalin is a β-cyano-glycoside in the bitter almond that is bound to cyano (CN), which releases free cyano groups after eating the bitter almond, so that the food is poisoned. Amygdalin is a product of the metabolism of phenylalanine in the bitter almond. Amygdalin has β-glucosidase and amygdalinase (oxynitrilase): the former catalyzed amygdalin into two molecules of glucose and one molecule of amygdalenone through hydrolysis; the later catalyzes mandelonitrile into almond nitrile cyanide (HCN) and benzaldehyde through hydrolysis. Amygdalin exists in seeds, such as almonds.
Many plant root cells contain glycosides, with no toxic effect when in sugar type. Glycosides hydrolysis produce toxic substances leading to cell death. Mandelic glycosides contained in peach root is a glycoside. Amylose hydrolysis produce two kinds of plant toxins-hydrogen cyanide and benzaldehyde. Peeling root lesion formation and necrosis occurred in the vicinity of the stabbed nematode but not in contact zone; in addition, in vitro tests have proved that the pratylenchus penetrans can make amygdalin hydrolysis.
As a cyanide containing glucoside, it can be used as a substrate for such as maltase, almond casein and β-glucosidase identification, differentiation and characterization.


Toxic substances

Toxicity classification

Highly toxic

Acute toxicity

Acute toxicity Oral-Rat LD50: 522 mg/kg; Oral-mouse LD50: 443 mg/kg

Flammability Hazardous properties

Combustible; producing toxic nitrogen oxides when heated.

Storage and transportation

Ventilation, low temperature, drying

Fire extinguishing agent

Dry powder, foam, sand, carbon dioxide

Chemical Properties



antiinflammatory, experimental antineoplastic


ChEBI: An amygdalin in which the stereocentre on the cyanohydrin function has R-configuration.

World Health Organization (WHO)

Laetrile, which consists mainly of amydgalin, a glycoside extracted from the kernels of apricots, peaches and other fruits, has been available for over 30 years in preparations purporting to be beneficial in the treatment of cancer. Although there is no evidence that these are efficacious, preparations continued to be widely used and, until the late 1970s, they were considered to be harmless. However, oral dosage forms, which may be broken down in the gut to hydrogen cyanide, have subsequently been shown to be potentially lethal. This has resulted in restrictive regulatory measures in several countries.

Purification Methods

D-Amygdalin recrystallises from water as the trihydrate, or from EtOH. It is present in bitter almonds. [Smith Chem Ber 64 1115 1931, Beilstein 17/8 V 188.]

Amygdalin Preparation Products And Raw materials

Raw materials

Preparation Products

Amygdalin Suppliers

Global( 275)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Rixing Chemical CO.,LTD
- CHINA 235 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 CHINA 552 55
Meihua Biological Technology Co.,Ltd
031145896235 CHINA 215 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-0311-66562153 whatsapp +8615203118427
+86-0311-66562153 CHINA 416 50
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 1669 55
Chengdu Biopurify Phytochemicals Ltd.
18080483897 CHINA 2238 58

View Lastest Price from Amygdalin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-03-05 Amygdalin
US $600.00 / KG 1KG 99.9% 100000 Hubei XinRunde Chemical Co., Ltd.
2018-05-03 Amygdalin
US $1.00 / UG 1UG 99.5% 1111111111111111 Meihua Biological Technology Co.,Ltd
2018-07-25 Amygdalin
US $10.00 / KG 10UG 99% 500kg/month Hebei Chisure Biotechnology Co., Ltd.

Amygdalin Spectrum

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