ChemicalBook >> CAS DataBase List >>5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole structure

CAS No.: 124750-51-2

Chemical Name:: 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

Synonyms: Losaint-B;ALSTint-A04;Valsartan IMP;Valsartan Impurity;Valsartan Impurity 8;Valsartan Impurity 9;TRITYLATED BROMO IMP;Valsartan impurity 19;Fimasartan Impurity B;Valsartan intermediate

CBNumber:: CB8369024

Molecular Formula:: C33H25BrN4

Molecular Weight:: 557.48

MDL Number:: MFCD00665221

MOL File:: 124750-51-2.mol

Last updated:2024-03-27 13:53:55

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5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Properties

Melting point	152-155°C
Boiling point	61°C/12mmHg(lit.)
Density	1.28±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	Soluble in Chloroform and Methanol (Sparingly)
form	Solid
pka	0.29±0.10(Predicted)
color	White
Stability	Moisture Sensitive
InChI	InChI=1S/C33H25BrN4/c34-24-25-20-22-26(23-21-25)30-18-10-11-19-31(30)32-35-36-37-38(32)33(27-12-4-1-5-13-27,28-14-6-2-7-15-28)29-16-8-3-9-17-29/h1-23H,24H2
InChIKey	ZTFVTXDWDFIQEU-UHFFFAOYSA-N
SMILES	N1(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C(C2=CC=CC=C2C2=CC=C(CBr)C=C2)=NN=N1
CAS DataBase Reference	124750-51-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02,GHS07
Signal word	Danger
Hazard statements	H315-H319-H228
Precautionary statements	P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313
RIDADR	UN 2811 6.1/PG III
HazardClass	6.1
PackingGroup	III

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T137073	5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-1H-TETRAAZOLE Aldrich	124750-51-2	10mg	$139	2024-03-01	Buy
Biosynth Carbosynth	FB19245	5-[4'-Bromomethyl-(1,1'-biphenyl)-2-yl]-1-triphenylmethyltetrazole	124750-51-2	50g	$150	2021-12-16	Buy
Biosynth Carbosynth	FB19245	5-[4'-Bromomethyl-(1,1'-biphenyl)-2-yl]-1-triphenylmethyltetrazole	124750-51-2	100g	$240	2021-12-16	Buy
AK Scientific	J11478	OlmesartanImpurity20	124750-51-2	100mg	$95	2021-12-16	Buy
Biosynth Carbosynth	FB19245	5-[4'-Bromomethyl-(1,1'-biphenyl)-2-yl]-1-triphenylmethyltetrazole	124750-51-2	25g	$100	2021-12-16	Buy

Product number	Packaging	Price	Buy
T137073	10mg	$139	Buy
FB19245	50g	$150	Buy
FB19245	100g	$240	Buy
J11478	100mg	$95	Buy
FB19245	25g	$100	Buy

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Chemical Properties,Uses,Production

Description

5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole is an intermediate in the synthesis of Losartan and Valsartan. Utilized for various purposes, 5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole has found application as a fluorescent probe to identify DNA damage. It serves as a photosensitizer in photodynamic therapy and acts as a catalyst in polymer synthesis. Furthermore, this compound functions as a fluorescent label to detect proteins and as a fluorescent indicator to detect metal ions.

Chemical Properties

Off-White Solid

Uses

Used as Olmesartan medoxomil related intermediate, Olmesartan medoxomil is an angiotensin II receptor antagonist^[1].

Application

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole is an important pharmaceutical intermediate. It can be used in the preparation of olmesartan medoxomil key intermediates, Losartan potassium, Valsartan, Candesartan and molecular sieve catalysts.

Hazard

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole has an acute toxin and is irritating to skin and eyes.

References

[1] HAI Z. Determination of the related substances in N-triphenylmethyl-5-(4’-bromomethylbiphenyl-2-yl-) terazole by HPLC[J]. West China Journal of Pharmaceutical Sciences, 2015.

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole synthesis

Synthesis of 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole from 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Preparation Products And Raw materials

Raw materials

Preparation Products

Trityl olmesartan Ethyl-2-Ethoxy-1-[[(2'-(1h-Tetrazol-5-Yl)Biphenyl-4-Yl)Methyl]Benzimidazole]-7-Carboxylate 1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester 1H-Imidazole-4,5-dicarbonitrile, 2-butyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]- diethyl 2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-4,5-dicarboxylate

2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde

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5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Suppliers

Global( 534)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sinopharm International Guangzhou Ltd.	+86-2038033341 +86-18520036739	zhuluqiang@sinopharm.com	China	77	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Hebei Dangtong Import and export Co LTD	+8615632927689	admin@hbdangtong.com	China	991	58
Hangzhou ICH Biofarm Co., Ltd	+undefined8613073685410	sales@ichemie.com	China	985	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55

Supplier	Advantage
Sinopharm International Guangzhou Ltd.	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Dangtong Import and export Co LTD	58
Hangzhou ICH Biofarm Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55

Genotoxic of N-(triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl)tetrazolium
N-(triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl)tetrazolium, is a chemical substance with the molecular formula C33H25BrN4,....
Sep 6，2022

View Lastest Price from 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-26	5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 124750-51-2	US $36.00-27.00 / kg	1kg	99%	5000kg	Hebei Dangtong Import and export Co LTD
2024-04-22	BBTT 124750-51-2	US $0.00 / KG	2KG	99% up, High Density	20 tons	Sinoway Industrial co., ltd.
2023-11-01	5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 124750-51-2	US $0.00-0.00 / kg	1kg	99.0%min	10tons	Hangzhou ICH Biofarm Co., Ltd

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
124750-51-2
US $36.00-27.00 / kg
99%
Hebei Dangtong Import and export Co LTD

BBTT
124750-51-2
US $0.00 / KG
99% up, High Density
Sinoway Industrial co., ltd.

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
124750-51-2
US $0.00-0.00 / kg
99.0%min
Hangzhou ICH Biofarm Co., Ltd

124750-51-2(5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole)Related Search:

4,4'-Dimethylbiphenyl Decabromodiphenyl oxide FIREMASTER BP-6 Biphenyl 2-Bromobiphenyl

2,3,5-Triphenyltetrazolium chloride 2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-4-Methyl-6-oxo-1,6-dihydropyriMidin-5-yl) -N,N-diMethylacetaMide Fimasartan 2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-5-pyrimidineacetamide 2-(2-butyl-4-hydroxy-6-MethylpyriMidin-5-yl)-N,N-diMethylacetaMide

OlMesartan MedoxoMil iMpurity V N-Trityl Olmesartan Ethyl Ester METHYL TRIPHENYLMETHYL ETHER 2-(2-butyl-4-Methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-1,6-dihydropyriMidin-5-yl)-N,N-diMethylethanethioaMide 4-(1-Methoxy-1-methylethyl)-2-propyl-1H-Imidazole-5-carboxylic acid ethyl ester

Diethyl 2-propylImidazoledicarbonate OlMesartan MedoxoMil Butyl IMpurity 4,5-Dimethyl-1,3-dioxol-2-one

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N-(Triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole N-(TRIPHENYLMETHYL)-5-(4'-BROMOMETHYLBIPHENYL-2-YL) TETRAZOLE 5-(4'-BROMOMETHYL-1,1'-BIPHENYL-2-YL)-1-TRIPHENYLMETHYL-1H-TETRAZOLE 5-(4'-BROMOMETHYL-BIPHENYL-2-YL)-1-TRITYL-1H-TETRAZOLE 1H-Tetrazole, 5-[4'-(bromomethyl)[1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)- Trityl tetrazole bromomethyl biphenyl 5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL- 5-[4'-(Bromomethyl)[1,1'-Biphenyl]-1-(Triphenylmethyl)Tetrazole] 2-(N-Triphenylmethyltetrazolyl)-4-Bromomethylbiphenyl)97% Valsartan intermediate 5-[4Bromomethyl-(1,1biphenyl)-2-yl]-1-triphenylmethyltetrazole N-(TRIPHENYLMETHYL)-5-(4''-BROMOMETHYLBIPHENYL-2-YL-)TETRAZOLE(BBTT) 5-[4'-bromomethyl-1,1'-biphenyl-2-yl]-1-trityl-1H-tetrazole (TRIPHENYLMETHYL)TETRAZOLE 5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-1H-TETRAAZOLE N-(Triphenylmethyl)-5-(4’-bromomethylbiphenyl-2-yi-)tetrazole N-(Triphenylmethyl)C5-(4'-Bromomethylbiphenyl-2Yl)Tetrazole n-(triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole,N-(Triphenyl methyl)-5-(4'-Bromomethyl-biphenyl-2-yl)tetrazole(TTBB,BBTT) 5-(4'-BroMoMethyl-1,1'-biphenyl-2-yl)-1-triphenylM 5-[5-(broMoMethyl)-2-phenylphenyl]-1-(triphenylMethyl)-1H-1,2,3,4-tetrazole Candesartan BroMo IMpurity：5-(4'-(BroMoMethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetrazole [2'-(1-Trityl-1H-tetrazol-5-yl)biphenyl-4-yl]Methyl BroMide 4-[2'-(N-TriphenylMethyltetrazol-5-yl)phenyl]benzyl BroMide 4'-BroMoMethyl-2-(1-trityl-1H-tetrazol-5-yl)biphenyl 4-BroMoMethyl-2'-[N-triphenylMethyl-1H-tetrazol-5-yl]biphenyl N-(Trityl)-5-(4'-BroMoMethyl Biphenyl-2-Yl)-Tetrazole Irbesartan BroMo IMpurity Losartan BroMo N1 Trityl IMpurity Valsartan BroMo IMpurity Irbesartan BroMo N1-Trityl IMpurity 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole N-(Triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole OlMesartan IMpurity (N-(TriphenylMethyl)-5-(4'-broMoMethylbiphenylyl)tetrazole) 5-(4'-(Bromomethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetrazole 200mg Desbutoxy Valsartan Benzyl Ester Candesartan Bromo N1-Trityl Impurity Valsartan Impurity N-(Tm)-5-(4'-bromomethylbiphenyl-2-yl ) tetrazole(TTBB) Valsartan Impurity 8 Valsartan Impurity 9 (R)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)propionamido)-3-methylbutanoic acid Valsartan IMP Valsartan impurity 19 5-[4'-(Bromomethyl)-1,1'-biphenyl-2-yl]-1-triphenylmethyl-1H-tetrazole> Irbesartan Bromo N2-Trityl Impurity 5-(4'-Bromomethyl-1,1'- biphenyl-2-yl)-1- triphenylmethyl-1Htetrazole （BBTT） 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole USP/EP/BP 1-Triphenylmethyl-5-[4'-(bromomethyl)biphenyl-2-yl]tetrazole DISCONTINUED, offer B685310 N-(Triphenylmethyl)-5-(4’bromomethyl-biphenyl-2- yl)tetrzole(TTBB) 5-(4'-Bromomethyl-1,1'biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole (TTB) 1-Triphenylmethyl-5-(4'-bromomethyl-1, 1'-biphenyl-2-yl)-1H-tetrazole N-(Triphenylmethyl)-5-(4'romomethyl)biphenyl-2-yl)tetrazole N-TRIPHENYLMETHYL)-5-(4-BROMOMETHYLBIPHENYL-2-YL-)TETRAZOLE (TTBB) N-(Triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole (TTBB) Losartan Bromo N1 Trityl Impurity/ Olmesartan Impurity N-(Triphenylmethyl)-5-(4’-bromomethylbiphenyl-2-yl)tetrazole Olmesartan Impurity N-(Triphenylmethyl)-5-(4’-bromomethylbiphenyl-2-yl)tetrazole/ Losartan Bromo N1 Trityl Impurity Azilsartan medoxomil impurity227 candesartan cilexetil impurity1357 Candesartan Bromo N1-Trityl ImpurityQ: What is Candesartan Bromo N1-Trityl Impurity Q: What is the CAS Number of Candesartan Bromo N1-Trityl Impurity Q: What is the storage condition of Candesartan Bromo N1-Trityl Impurity Q: What are the applications of Candesartan Bromo N1-Trityl Impurity Fimasartan Impurity B