ChemicalBook >> CAS DataBase List >>4-Hydroxy-D-(-)-2-phenylglycine
4-Hydroxy-D-(-)-2-phenylglycine
- CAS No.
- 22818-40-2
- Chemical Name:
- 4-Hydroxy-D-(-)-2-phenylglycine
- Synonyms
- (R)-2-AMino-2-(4-hydroxyphenyl)acetic acid;H-D-PHG(4-OH)-OH;D-4-HYDROXYPHENYLGLYCINE;4-HYDROXY-D-PHENYLGLYCINE;(R)-(-)-2-Phenylglycine amide;AMoxicillin Related CoMpound I;(2R)-2-amino-2-(4-hydroxyphenyl)acetic acid;B8372699;H-D-HPG-OH;D-4-OH-Phg-OH
- CBNumber:
- CB8372699
- Molecular Formula:
- C8H9NO3
- Molecular Weight:
- 167.16
- MDL Number:
- MFCD00004262
- MOL File:
- 22818-40-2.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Product description | Number | Pack Size | Price |
| Cefprozil impurity A European Pharmacopoeia (EP) Reference Standard | Y0001372 | 25 mg | $118 |
| Amoxicillin Related Compound I | PHR2196 | 50MG | $499 |
| H1430000 | 25 mg | $153 | |
| Amoxicillin Related Compound I United States Pharmacopeia (USP) Reference Standard | 1031591 | 25mg | $1300 |
| 4-Hydroxy-D-phenylglycine ≥98% | 215333 | 25g | $50.1 |
| More product size | |||
| Melting point | 240 °C (dec.)(lit.) |
|---|---|
| alpha | -156 º (c=1, 1 N HCl) |
| Boiling point | 295.73°C (rough estimate) |
| Density | 1.396 |
| vapor pressure | 0Pa at 25℃ |
| refractive index | -158 ° (C=1, 1mol/L HCl) |
| storage temp. | 2-8°C |
| solubility | 5g/l |
| pka | 2.15±0.10(Predicted) |
| form | Liquid |
| color | Clear colorless to yellow |
| optical activity | [α]23/D 158±3°, c = 1 in 1 M HCl |
| Water Solubility | 5 g/L (20 ºC) |
| BRN | 2210998 |
| LogP | -2.25 |
| CAS DataBase Reference | 22818-40-2(CAS DataBase Reference) |
| FDA UNII | PCM9OIX717 |
| EPA Substance Registry System | Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.R)- (22818-40-2) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29225000 | |||||||||
| NFPA 704 |
|
4-Hydroxy-D-(-)-2-phenylglycine price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001372 | Cefprozil impurity A European Pharmacopoeia (EP) Reference Standard | 22818-40-2 | 25 mg | $118 | 2025-07-31 | Buy |
| Sigma-Aldrich | PHR2196 | Amoxicillin Related Compound I | 22818-40-2 | 50MG | $499 | 2025-07-31 | Buy |
| Sigma-Aldrich | H1430000 | 22818-40-2 | 25 mg | $153 | 2025-07-31 | Buy | |
| Sigma-Aldrich | 1031591 | Amoxicillin Related Compound I United States Pharmacopeia (USP) Reference Standard | 22818-40-2 | 25mg | $1300 | 2025-07-31 | Buy |
| Sigma-Aldrich | 215333 | 4-Hydroxy-D-phenylglycine ≥98% | 22818-40-2 | 25g | $50.1 | 2023-06-20 | Buy |
4-Hydroxy-D-(-)-2-phenylglycine Chemical Properties,Uses,Production
Description
d-(p-Hydroxyphenyl)glycine (d-HPG) is widely used in large amounts as an important intermediate for the synthesis of amoxicillin and several other semisynthetic β-lactam antibiotics.
Chemical Properties
off-white powder
Uses
4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurity A(Amoxicillin EP Impurity A)) is an compound used mainly for the synthetic preparation of β-lactam antibiotics.
Uses
4-Hydroxy-D-(-)-2-phenylglycine is an compound used mainly for the synthetic preparation of β-lactam antibiotics.
Definition
ChEBI: The D-enantiomer of 4-hydroxyphenylglycine. A non-proteinogenic amino acid found in Herpetosiphon aurantiacus.
Flammability and Explosibility
Non flammable
reaction suitability
reaction type: solution phase peptide synthesis
Purification Methods
Crystallise it from water and dry it in vacuo. [Beilstein 14 I 659.]
4-Hydroxy-D-(-)-2-phenylglycine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 563)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8770 | 58 |
| Sichuan Zhuoyu Yantang Technology Co., Ltd. | +8613288715578 | sales@sichuanzyyt.com | China | 12242 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Apeloa production Co.,Limited | +8619933239880 | admin@apcl.com.cn | China | 861 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13505 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21616 | 55 |
View Lastest Price from 4-Hydroxy-D-(-)-2-phenylglycine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-06 | 4-Hydroxy-D-(-)-2-phenylglycine
22818-40-2
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-11-03 | Cefprozil Impurity A
22818-40-2
|
US $0.00-0.00 / mg | 10mg | 90%+ | 10g | Guangzhou PI PI BIOTECH INC | |
 |
2025-11-03 | 4-Hydroxy Phenylglycine
22818-40-2
|
US $0.00-0.00 / mg | 10mg | 90%+ | 10g | Guangzhou PI PI BIOTECH INC |
-
- 4-Hydroxy-D-(-)-2-phenylglycine
22818-40-2
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Cefprozil Impurity A
22818-40-2
- US $0.00-0.00 / mg
- 90%+
- Guangzhou PI PI BIOTECH INC
-
- 4-Hydroxy Phenylglycine
22818-40-2
- US $0.00-0.00 / mg
- 90%+
- Guangzhou PI PI BIOTECH INC
22818-40-2(4-Hydroxy-D-(-)-2-phenylglycine)Related Search:
(R)-4-HYDROXYPHENYLGLYCINE
(R)-(-)-2-(4-HYDROXYPHENYL)GLYCINE
D-(-)-2-(4-HYDROXYPHENYL)GLYCINE
D(-)-2-(P-HYDROXYPHENYL)GLYCINE
D-(-)-A-4-HYDROXYPHENYLGLYCINE
D-4-HYDROXYPHENYLGLICYNE
D-(-)-4-HYDROXYPHENYLGLYCINE
D-ALPHA-PARA-HYDROXYPHENYLGLYCINE
(D)-(-)-ALFA-4-HYDROXYPHENYL GLYCINE
D-(-)-P-HYDROXYPHENYLGLYCINE
D-P-HYDROXYPHENYLGLYCINE
D(-)PARA-HYDROXY-PHENYLGLYCINE
HYDROXY PHENYL GLYCINE
H-D-HPG-OH
H-D-PHG(4-HYDROXY)-OH
(theta)-benzeneaceticaci
.alpha.-amino-4-hydroxy-,(R)-Benzeneaceticacid
a-Amino-p-hydroxyphenylaceticacid
Benzeneaceticacid,alpha.-amino-4-hydroxy-,(R)-
Benzeneaceticacid,-amino-4-hydroxy-,(R)-
L-(-)-4-Hydroxy-α-aminophenylacetic acid
D(-)-P-Hydroxyphenylglycine, 98+%
(2R)-2-(4-Hydroxyphenyl)glycine
(R)-2-(p-Hydroxyphenyl)glycine
p-Hydroxy-D-phenylglycine
α-(4-Hydroxyphenyl)-D-glycine
(2R)-2-Amino-2-(4-hydroxyphenyl)ethanoic acid, (R)-Amino(4-hydroxyphenyl)acetic acid
Amoxicillin Related Compound I (15 mg) ((R)-2-Amino-2-(4-hydroxyphenyl)acetic acid)
D(-)-4-Hydroxyphenylglycine, 98+% 100GR
D(-)-4-Hydroxyphenylglycine, 98+% 25GR
D(-)-4-Hydroxyphenylglycine ,99%
D(-)-alpha-para-Hydroxyphenylglycine base
(R)-(-)-2-Amino-2-(4-hydroxyphenyl)acetic Acid
4-Hydroxy-D-phenylglycine
Benzeneacetic acid, a-aMino-4-hydroxy-, (aR)-
4-Hydroxy-D-(-)-2-phenylglycine
AMoxicillin EP IMpurity I
(-)-4-Hydroxy-D-phenylglycine, 98+%
D-(-)p-hydroxyphenylgcine Dane salt
4-Hydroxy-D-(-)-2-phenylglycine, 99.0%(LC&T
D(-)-4-Hydroxyphenylglycine
4-Hydroxy-D-phenylglycine
Cefprozil impurity A
Cefadroxyl impurity A
D-N-(4-hydroxyphenyl)glycine
Parahydroxy phenylglycine base
D-a-(-)-parahydroxyphenylgycine
(2R)-2-amino-(4-Hydroxyphenyl)acetic acid
D-4-HYDROXYPHENYLGLYCINE, 98+%
d-p-hydroxyglycine
(2R)-amino(4-hydroxyphenyl)acetic acid
2-(4-Hydroxy-phenyl)glycin D-Form
D-(-)-p-Hydroxy
Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.R)-
(r)-(-)-à-amino-(4-hydroxyphenyl)acetic acid
D(-)-P-HYDROXYPHENYLGLYCINE BASE
(R)-(-)-2-(4-HYDROXYPHENYL)GLYCINE 99+%
(R)-(4-HYDROXYPHENYL)GLYCINE (4-HYDROXY-D-PHENYLGLYCINE)
D-(-)-4-HYDROXYPHENYLGLYCINE, NA OR K SALT
PARA-HYDROXYPHENYLGLYCINE
