ChemicalBook >> CAS DataBase List >>Gomisin A
Gomisin A
- CAS No.
- 58546-54-6
- Chemical Name:
- Gomisin A
- Synonyms
- D01752;TJN-101;GOMISIN A;Besigomsin;BESIGOMISIN;wuweizichunb;SCHIZANDROL B;SCHISANDROL B;wuweizialcoholb;Grifola frondsa
- CBNumber:
- CB8374224
- Molecular Formula:
- C23H28O7
- Molecular Weight:
- 416.47
- MDL Number:
- MFCD01941645
- MOL File:
- 58546-54-6.mol
- MSDS File:
- SDS
Last updated:2023-06-08 17:06:38
| Melting point | 88.5°C |
|---|---|
| Boiling point | 454.79°C (rough estimate) |
| Density | 1.1772 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO : 50 mg/mL (120.06 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | powder to crystal |
| pka | 14.58±0.40(Predicted) |
| color | White to Light yellow |
| LogP | 4.770 (est) |
| FDA UNII | L5U70J87J8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P501-P270-P264-P301+P312+P330 | |||||||||
| Safety Statements | 24/25 | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
Gomisin A price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | G0537 | Gomisin A | 58546-54-6 | 5MG | $72 | 2024-03-01 | Buy |
| TCI Chemical | G0537 | Gomisin A | 58546-54-6 | 25MG | $258 | 2024-03-01 | Buy |
| Cayman Chemical | 25149 | Schisandrol B ≥98% | 58546-54-6 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 25149 | Schisandrol B ≥98% | 58546-54-6 | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 25149 | Schisandrol B ≥98% | 58546-54-6 | 10mg | $169 | 2024-03-01 | Buy |
Gomisin A Chemical Properties,Uses,Production
Description
Schisandrol B is a lignan originally isolated from S. chinensis that has hepatoprotective activity. It increases the expression of pregnane X receptor (PXR) target genes involved in bile acid metabolism, including Cyp3a11, Ugt1a1, Oatp2, and Mrp3 in mouse liver and CYP3A4, UGT1A1, and OATP2 in HEK293T cells. It also protects against lithocholic acid-induced hepatic necrosis and intrahepatic cholestasis in wild-type, but not Pxr-null, mice and decreases mortality in a mouse model of cholestasis when administered at a dose of 100 mg/kg twice per day. It also promotes liver regeneration following partial hepatectomy and protects against hepatotoxicity induced by acetaminophen .
Chemical Properties
White powder
Uses
Schizandrol B exhibits potent protective effects of on ET-1-induced dysfunctional human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs). Anti-cholestasis effect.
Gomisin A Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 219)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
View Lastest Price from Gomisin A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | Gomisin A
58546-54-6
|
US $0.00-0.00 / mg | 20mg | 98% HPLC | 100kg | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2023-02-24 | Gomisin A
58546-54-6
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2022-10-12 | Gomisin A
58546-54-6
|
US $1.00 / kg | 1kg | 99% | 5000 Ton | Hebei Duling International Trade Co. LTD |
58546-54-6(Gomisin A)Related Search:
Silibinin
Ginkgo biloba extract
WUWEIZISU C
(5S)-6α,7β-Dimethyl-1,2,3,11,12-pentamethoxy(5,6,7,8-tetrahydrodibenzo[a,c]cyclooctene)-5α,6β,10-triol 5-benzoate
2-BUTENOIC ACID, 2-METHYL-, (5S,6S,7S,13AS)-5,6,7,13A-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YL ESTER, (2Z)-
1of4
2,3,13-tetramethoxy-l-stereoisomer
benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-6-ol,5,6,7,8-tetrahydro-6,7-dimethy
wuweizialcoholb
wuweizichunb
BESIGOMISIN
GOMISIN A
SCHISANDROL B
SCHIZANDROL B
Besigomsin
Besigomsin (jan/inn)
D01752
Gomisin A/Schisandrin
(6S,7S)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6β,7β-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6α-ol
TJN-101
Schizandrol B, froM Schisandra chinensis
Schisandrol B (Gomisin-A
Schizandrol B, 98%, from Schisandra chinensis (Turcz.) Baill.
Gomisin A Standard
Grifola frondosa (Dicks.) Gray
Grifola frondsa
Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6S,7S,13aR)-
Schizandrol B，Gomisin A
(6S,7S)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
(6S,7S,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol
(6S,7S,13aR)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
Schisandrin ethyl alcohol
(6S,7S,13aR)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
58546-54-6
58546-54-8
C23H28O7
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Miscellaneous Natural Products