Clorsulon
- CAS No.
- 60200-06-8
- Chemical Name:
- Clorsulon
- Synonyms
- chlorsulon;CLORSULON USP;orsuL;MK-401;l631529;curatrem;CLORSULON;keluosuolong;Clorsulon (MK-401;Clorsulon (200 mg)
- CBNumber:
- CB8375438
- Molecular Formula:
- C8H8Cl3N3O4S2
- Molecular Weight:
- 380.66
- MDL Number:
- MFCD00072006
- MOL File:
- 60200-06-8.mol
- MSDS File:
- SDS
| Melting point | 194-203°C |
|---|---|
| Boiling point | 651.7±65.0 °C(Predicted) |
| Density | 1.800±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 9.16±0.60(Predicted) |
| color | White |
| CAS DataBase Reference | 60200-06-8(CAS DataBase Reference) |
| FDA 21 CFR | 556.163 |
| EWG's Food Scores | 1 |
| FDA UNII | EG1ZDO6LRD |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | CZ9090000 | |||||||||
| HS Code | 29350090 | |||||||||
| Toxicity | LD50 in mice (mg/kg): 761 i.p.; >10,000 orally (Ostlind) | |||||||||
| NFPA 704 |
|
Clorsulon price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 33973 | Clorsulon VETRANAL?, analytical standard | 60200-06-8 | 100mg | $124 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1140702 | Clorsulon United States Pharmacopeia (USP) Reference Standard | 60200-06-8 | 200mg | $436 | 2024-03-01 | Buy |
| Cayman Chemical | 30288 | Clorsulon | 60200-06-8 | 50mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 30288 | Clorsulon | 60200-06-8 | 100mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 30288 | Clorsulon | 60200-06-8 | 250mg | $239 | 2024-03-01 | Buy |
Clorsulon Chemical Properties,Uses,Production
Description
Clorsulon is a sulfonamide antiparasitic agent. It induces swelling and blebbing and reduces motility of F. hepatica mature flukes when used at a concentration of 10 μg/ml. In vivo, clorsulon (3.5-15 mg/kg) reduces the number of flukes in a goat model of F. hepatica infection. It completely eradicates naturally acquired F. hepatica adult flukes in sheep and cattle when administered at a dose of 7 mg/kg. Formulations containing clorsulon have been used in the treatment of liver flukes in sheep and cattle.
Chemical Properties
Crystalline Solid
Uses
A benzenedisulfonamide derivative with fasciolicidal activity. Anthelmintic (Trematodes).
Uses
analgesic, antiinflammatory
Definition
ChEBI: 4-amino-6-(1,2,2-trichloroethenyl)benzene-1,3-disulfonamide is a sulfonamide and a member of benzenes.
brand name
Curatrem [Veterinary] (Merial).
Veterinary Drugs and Treatments
Clorsulon is approved for use in the treatment of immature and adult forms of Fasciola hepatica (Liver fluke) in cattle. It is not effective against immature flukes less than 8 weeks old. It also has activity against Fasciola gigantica. Although not approved, the drug has been used in practice in various other species (e.g., sheep, llamas). It has activity against F. magna in sheep, but is not completely effective in eradicating the organism after a single dose, thus severely limiting its clinical usefulness against this parasite. Clorsulon is also not effective against the rumen fluke (Paramphistomum).
Clorsulon Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Harvest Chemical CO.,Ltd | +86-13129915771 +86-15623179893 | wendy@hb-harvestchem.com | China | 931 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
View Lastest Price from Clorsulon manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-08 | Clorsulon
60200-06-8
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd | |
 |
2023-09-14 | Clorsulon
60200-06-8
|
US $0.00-0.00 / g | 100g | 99% | 20 tons | Wuhan Han Sheng New Material Technology Co.，Ltd | |
 |
2023-06-10 | Clorsulon
60200-06-8
|
US $150.00 / kg | 1kg | 99.9% | 10000MT | Henan Bao Enluo International TradeCo.，LTD |