(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol
- CAS No.
- 1382486-90-9
- Chemical Name:
- (2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol
- Synonyms
- (R)-FTY720-OME;Benzenebutanol, β-amino-β-(methoxymethyl)-4-octyl-, (βR)-;(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol
- CBNumber:
- CB83945610
- Molecular Formula:
- C20H35NO2
- Molecular Weight:
- 321.4974
- MDL Number:
- MFCD28143604
- MOL File:
- 1382486-90-9.mol
(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Chemical Properties,Uses,Production
Definition
ChEBI: (2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol is a 2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol that has R-configuration. It is a sphingosine kinase-2 inhibitor. It has a role as an EC 2.7.1.91 (sphingosine kinase) inhibitor.
General Description
(R)-FTY720-OMe is a structural analogue of FTY720 which acts as a specific competitive inhibitor of sphingosine kinase 2 (SK2). Furthermore, (R)-FTY720-OMe does not inhibit sphingosine kinase 1 (SK1) activity.
Biochem/physiol Actions
(R)-FTY720-OMe helps to block DNA synthesis and actin rearrangement induced by sphingosine 1-phosphate (S1P) in MCF-7 breast cancer cells. It can also reduce sphingosine kinase 2 (SK2) expression and prevent DNA synthesis in HEK 293 cells. (R)-FTY720-OMe has anti-breast cancer potential.
(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Preparation Products And Raw materials
Raw materials
Preparation Products
(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Creative Enzymes | 58 |
| Sigma-Aldrich | 80 |