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DUP-697

DUP-697 Structure
DUP-697 structure
CAS No.
88149-94-4
Chemical Name:
DUP-697
Synonyms
BFMeT;DUP-697;DuP697,DuP 697;DuP-697 Assay Reagent;5-BROMO-2-(4-FLUOROPHENYL)-3-(4-(METHYLSULFONYL)PHENYL)THIOPHENE;Thiophene, 5-bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-
CBNumber:
CB8397180
Molecular Formula:
C17H12BrFO2S2
Molecular Weight:
411.31
MDL Number:
MFCD02684527
MOL File:
88149-94-4.mol
Last updated:2023-09-04 15:51:00
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DUP-697 Properties

storage temp. 2-8°C
solubility DMF: 54 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 15 mg/ml; Ethanol: 7 mg/ml
form White to off-white solid.
FDA UNII MRWLZPOFPA

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36

DUP-697 price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 70645 DuP-697 ≥98% 88149-94-4 5mg $110 2024-03-01 Buy
Cayman Chemical 70645 DuP-697 ≥98% 88149-94-4 10mg $175 2024-03-01 Buy
Cayman Chemical 70645 DuP-697 ≥98% 88149-94-4 25mg $407 2024-03-01 Buy
Cayman Chemical 70645 DuP-697 ≥98% 88149-94-4 50mg $757 2024-03-01 Buy
Tocris 1430 DuP697 ≥99%(HPLC) 88149-94-4 50 $738 2021-12-16 Buy
Product number Packaging Price Buy
70645 5mg $110 Buy
70645 10mg $175 Buy
70645 25mg $407 Buy
70645 50mg $757 Buy
1430 50 $738 Buy

DUP-697 Chemical Properties,Uses,Production

Description

DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2. When tested on isolated recombinant enzymes, DuP-697 is at least 50 times more potent in the inhibition of COX-2 than COX-1. The IC50 values for human recombinant COX-2 are 80 and 40 nM at 5 and 10 minutes, respectively. The IC50 for the inhibition of human recombinant COX-1 after the same time intervals is 9 μM. DuP-697 also attenuates the COX-1 inhibitory activity of non-selective COX inhibitors such as indomethacin.

Uses

DuP-697 is a thiophene that inhibits COX-2 and acts as a NSAID.

Definition

ChEBI: DuP 697 is a member of thiophenes.

Biological Activity

Potent and selective inhibitor of cyclooxygenase-2 (IC 50 values are 10 and 800 nM for COX-2 and COX-1 respectively). Inhibits prostaglandin synthesis and is anti-inflammatory in vivo . Orally active.

storage

Store at +4°C

DUP-697 Preparation Products And Raw materials

Raw materials

Preparation Products

DUP-697 Suppliers

Global( 70)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hebei Miaoyin Technology Co.,Ltd 		+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3582 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Jiangsu shring Biopharma Co., Ltd. +8613372282299 sales@shringchem.com China 3545 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Shanghai Hekang Biotechnology Co., Ltd. 18939837085 youchemicals@gmail.com China 1813 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Henan CoreyChem Co., Ltd 0371-86658258 info@coreychem.com China 10457 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
Hebei Miaoyin Technology Co.,Ltd 		58
Aladdin Scientific 		58
Jiangsu shring Biopharma Co., Ltd. 58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Shanghai Hekang Biotechnology Co., Ltd. 55
EMMX Biotechnology LLC 60
Henan CoreyChem Co., Ltd 58
Shanghai EFE Biological Technology Co., Ltd. 58

DUP-697 Spectrum

DUP-697(88149-94-4)1HNMR

88149-94-4(DUP-697)Related Search:

NS-398 Indometacin Piroxicam (S)-(+)-Ibuprofen Ibuprofen
Phenidone (R)-(-)-IBUPROFEN 4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE Meloxicam Naproxen
MECLOFENAMATE SODIUM SC-560 Sulindac sulfide APHS N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE
2-(4-Fluorophenyl)-thiophene DUP-697 2-BROMO-5-PHENYLTHIOPHENE

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DUP-697 5-BROMO-2-(4-FLUOROPHENYL)-3-(4-(METHYLSULFONYL)PHENYL)THIOPHENE BFMeT DuP-697 Assay Reagent Thiophene, 5-bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]- DuP697,DuP 697 88149-94-4 C17H12BrFO2S2 Lipid signaling API intermediates