2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
![2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Structure](StructureFile/ChemBookStructure3/GIF/CB8409227.gif)
- CAS No.
- 139047-55-5
- Chemical Name:
- 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
- Synonyms
- 3-MPPI;2-PMDQ;2 PMDQ,2PMDQ;2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE;Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[(4-phenyl-1-piperazinyl)methyl]-
- CBNumber:
- CB8409227
- Molecular Formula:
- C21H23N5O
- Molecular Weight:
- 361.44
- MDL Number:
- MFCD00673885
- MOL File:
- Mol file
Last updated:2023-07-21 08:27:59
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P637005 | 2-PMDQ | 139047-55-5 | 10mg | $165 | 2021-12-16 | Buy |
| Usbiological | 254372 | 2-PMDQ | 139047-55-5 | 10mg | $418 | 2021-12-16 | Buy |
| TRC | P637005 | 2-PMDQ | 139047-55-5 | 50mg | $670 | 2021-12-16 | Buy |
| ApexBio Technology | B6382 | 2-PMDQ | 139047-55-5 | 50mg | $723 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004260 | 2-PMDQ 95.00% | 139047-55-5 | 5MG | $501.89 | 2021-12-16 | Buy |
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Chemical Properties,Uses,Production
Uses
2-PMDQ is an analog of Ketanserin with beneficial hemodynamic effects in portal hypertensive rats. Anti-hypertensive effects.
Definition
ChEBI: 2-[(4-phenyl-1-piperazinyl)methyl]-3,6-dihydro-2H-imidazo[1,2-c]quinazolin-5-one is a member of piperazines.
Biological Activity
Very potent ligand for α 1 sites (K i for displacement of prazosin = 0.2 nM). Also binds to 5-HT 1A sites (K i = 50 nM).
Synthesis of 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE from 1-Phenylpiperazine and 2-(BROMOMETHYL)-2,6-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(3H)-ONE
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Suppliers
Global( 20)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9440 | 58 |
| Jinan ponder chemical co. LTD | 0531-0000 | thinklifescience@163.com | China | 19690 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1249 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
2-PMDQ
3-MPPI
Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[(4-phenyl-1-piperazinyl)methyl]-
2 PMDQ,2PMDQ
139047-55-5