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Galangin

Galangin
Galangin structure
CAS No.
548-83-4
Chemical Name:
Galangin
Synonyms
Galengin;GALANGIN;NORIZALPININ;GALANGIN hplc;Galangin, >=98%;Galangin Standard;GALANGIN WITH HPLC;7-Trihydroxyflavone;3,5,7-trihydroxy-flavon;3,5,7-TRIHYDROXYFLAVONE
CBNumber:
CB8413460
Molecular Formula:
C15H10O5
Formula Weight:
270.24
MOL File:
548-83-4.mol

Galangin Properties

Melting point:
214-215 °C(lit.)
Boiling point:
333.35°C (rough estimate)
Density 
1.2319 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
room temp
pka
6.32±0.40(Predicted)
Merck 
14,4339
BRN 
272179
InChIKey
VCCRNZQBSJXYJD-UHFFFAOYSA-N
CAS DataBase Reference
548-83-4(CAS DataBase Reference)
FDA UNII
142FWE6ECS
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280a-P304+P340-P405-P501a-P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
RTECS  LK9275500
10
HS Code  29329990

Galangin price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 282200 Galangin autophagy inducing flavonoid 548-83-4 25mg $151 2021-03-22 Buy
Sigma-Aldrich 282200 Galangin autophagy inducing flavonoid 548-83-4 100mg $468 2021-03-22 Buy
Alfa Aesar L14223 3,5,7-Trihydroxyflavone, 97% 548-83-4 100mg $257 2021-03-22 Buy
Alfa Aesar L14223 3,5,7-Trihydroxyflavone, 97% 548-83-4 25mg $94.9 2021-03-22 Buy
Cayman Chemical 15948 Galangin ≥98% 548-83-4 5mg $39 2021-03-22 Buy

Galangin Chemical Properties,Uses,Production

Chemical Properties

Yellow powder

Uses

CYP1A1 inhibitor, vasodilator

Uses

Galangin is a flavanoid found in Alpinia officinarum, galangal rhizome (Alpinia galanga) and in propolis. Galangin has been show to inhibit proliferation of estrogen receptor-positive MCF-7 human brea st cancer cells as well as delay of mammary tumorigenesis.

Definition

ChEBI: A 7-hydroxyflavonol with additional hydroxy groups at positions 3 and 5 respectively.

Anticancer Research

Galangin is a flavonol that is derived from Alpinia officinarum, a plant from the gingerfamily, grown in Southeast Asia. The extract from the rhizome suppresses cellproliferation of hepatocellular carcinoma cells (Su et al. 2013). ER stress is inducedby galangin as is evident by rise in concentration of cytosolic Ca2+ and other UPRtarget genes like CHOP, GRP 78 and GRP 94. The ER is a major storage site forintracellular calcium. Normal functioning of ER chaperones is disrupted by calciumexhaustion in ER which produces ER stress and hence activation of UPR (Hotamisligil2010; Mekahli et al. 2011). CHOP and 4-polybutyric acid siRNA, well-known ERstress inhibitor, substantially blocked stress induced by galangin in the HCC cell line.To sum up, ER stress is upregulated by galangin, inhibiting cancer cell proliferation,and galangin can prove to be an effective anticancer agent (Su et al. 2013).

Galangin Preparation Products And Raw materials

Raw materials

Preparation Products


Galangin Suppliers

Global( 266)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 20010 60
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21032 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967
kaia@neputrading.com CHINA 1011 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29961 58
Chengdu GLP biotechnology Co Ltd
13350802083 028-87075086
scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
18482058008 18080483897
maggie@biopurify.com CHINA 2712 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58

View Lastest Price from Galangin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-13 Galangin
548-83-4
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10 Galangin
548-83-4
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2021-06-08 Galangin
548-83-4
US $10.00 / KG 10ASSAYS 99% 500kg/month Shanxi Naipu Import and Export Co.,Ltd

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