N-ACETYLPROCAINAMIDE
- CAS No.
- 32795-44-1
- Chemical Name:
- N-ACETYLPROCAINAMIDE
- Synonyms
- acekainid;acecainide;TIMTEC-BB SBB005970;N-ACETYLPROCAINAMIDE;n-acetyloprokainamid;N-ACETYLPROCAINAMIDE, 99+%;N-ACETYLPROCAINAMIDE USP/EP/BP;4-acetamido-N-(2-(diethylamino)ethyl)benzamide;4’-((2-(diethylamino)ethyl)carbamoyl)acetanilide;4’-((2-(diethylamino)ethyl)carbamoyl)-acetanilid
- CBNumber:
- CB8432449
- Molecular Formula:
- C15H23N3O2
- Molecular Weight:
- 277.36
- MDL Number:
- MFCD00009052
- MOL File:
- 32795-44-1.mol
- MSDS File:
- SDS
| Melting point | 138-140 °C(lit.) |
|---|---|
| Boiling point | 500.0±35.0 °C(Predicted) |
| Density | 1.097±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | soluble1%, clear, colorless to faintly yellow (1N HCl) |
| pka | 14.54±0.46(Predicted) |
| Merck | 13,20 |
| FDA UNII | 910Q707V6F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | AE1974350 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
N-ACETYLPROCAINAMIDE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 269476 | N-Acetylprocainamide ≥99% | 32795-44-1 | 250mg | $62.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 269476 | N-Acetylprocainamide ≥99% | 32795-44-1 | 1g | $176 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | CHM0031256 | N-ACETYLPROCAINAMIDE 95.00% | 32795-44-1 | 1G | $681.09 | 2021-12-16 | Buy |
| ChemScene | CS-4707 | N-Acetylprocainamide ≥98.0% | 32795-44-1 | 100mg | $60 | 2021-12-16 | Buy |
| CSNpharm | CSN11506 | N-Acetylprocainamide | 32795-44-1 | 100mg | $48 | 2021-12-16 | Buy |
N-ACETYLPROCAINAMIDE Chemical Properties,Uses,Production
Originator
Acecainide ,ZYF Pharm Chemical
Uses
antiprotozoal
Uses
N-acetylprocainamide (NAPA) was used as a model drug in the study of establishing a quantitative approach to predict the renal clearances of basic drugs using N-1-methylnicotinamide (NMN).
Definition
ChEBI: A benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine.
Manufacturing Process
1.0 g of p-amino-N-(2-diethylaminoethyl)benzamide is dissolved in
chloroform. A few ice cubes are added to the solution. Acetyl chloride is added
dropwise with stirring until no more white precipitate forms; the latter is
separated by filtering under suction. The precipitate is washed with cold
acetone and dried overnight in a vacuum oven at room temperature. The
product is dissolved in a minimum amount of hot isopropanol and allowed to
precipitate in the cold. The p-acetamido-N-(2-diethylaminoethyl)benzamide
hydrochloride, is recrystallized a second time from hot isopropanol, melting
point 190°-193°C.
The free base is obtained from the hydrochloride by dissolving the latter in
water, adjusting the pH to greater than 10 with dilute sodium hydroxide, and
adding an equal volume of benzene. After shaking in a separatory funnel, the
benzene layer is recovered and evaporated to dryness. So the p-acetamido-N-
(2-diethylaminoethyl)benzamide is obtained.
Therapeutic Function
Antiarrhythmic
General Description
The relaxant effects of N-acetylprocainamide on bovine tracheal smooth muscle was studied.
N-ACETYLPROCAINAMIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3791 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9553 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29474 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
View Lastest Price from N-ACETYLPROCAINAMIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | N-ACETYLPROCAINAMIDE USP/EP/BP
32795-44-1
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2021-07-20 | N-AcetylprocainaMide
32795-44-1
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd |
-
- N-ACETYLPROCAINAMIDE USP/EP/BP
32795-44-1
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- N-AcetylprocainaMide
32795-44-1
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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