2-Bromoisobutyryl Bromide

CAS No.
20769-85-1
Chemical Name:
2-Bromoisobutyryl Bromide
Synonyms
BIBB;2-Bromo-2-methylpropanoyl bromide;2-BROMO-2-METHYLPROPIONYL BROMIDE;α-Bromoisobutyryl bromide;A-BROMOISOBUTYRYL BROMIDE;2-Bromoisobutyric acid bromide;2-Bromo-2-methyl;2-BROMOISOBUTYRYL BROMIDE;2-broMoisobutylyl broMide;α-Bromoisobutyryl bromide
CBNumber:
CB8440211
Molecular Formula:
C4H6Br2O
Molecular Weight:
229.9
MDL Number:
MFCD00000122
MOL File:
20769-85-1.mol
MSDS File:
SDS
Last updated:2023-10-17 13:55:13

2-Bromoisobutyryl Bromide Properties

Boiling point 162-164 °C(lit.)
Density 1.86 g/mL at 20 °C
refractive index n20/D 1.507(lit.)
Flash point >110°C
storage temp. Store below +30°C.
solubility Miscible with acetone and carbon disulfide.
form Liquid
Specific Gravity 1.860 (20/4℃)
color Clear light yellow to yellow
Water Solubility reacts
Sensitive Moisture Sensitive
BRN 1746128
Stability Stable, but may react with moisture. Incompatible with water, strong oxidizing agents, strong bases.
CAS DataBase Reference 20769-85-1(CAS DataBase Reference)
FDA UNII 627F9N9DYA
NIST Chemistry Reference Propanoyl bromide, 2-bromo-2-methyl-(20769-85-1)
EPA Substance Registry System Propanoyl bromide, 2-bromo-2-methyl- (20769-85-1)

SAFETY

Risk and Safety Statements

NFPA 704
1
3 1

2-Bromoisobutyryl Bromide price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 252271 α-Bromoisobutyryl bromide 98% 20769-85-1 100g $59.7 2023-06-20 Buy
Sigma-Aldrich 252271 α-Bromoisobutyryl bromide 98% 20769-85-1 500g $199 2023-06-20 Buy
TCI Chemical B0607 2-Bromoisobutyryl Bromide >98.0%(GC) 20769-85-1 25g $28 2023-06-20 Buy
TCI Chemical B0607 2-Bromoisobutyryl Bromide >98.0%(GC) 20769-85-1 100g $46 2023-06-20 Buy
Alfa Aesar B24249 2-Bromoisobutyryl bromide, 97% 20769-85-1 25g $33.2 2023-06-20 Buy
Product number Packaging Price Buy
252271 100g $59.7 Buy
252271 500g $199 Buy
B0607 25g $28 Buy
B0607 100g $46 Buy
B24249 25g $33.2 Buy

2-Bromoisobutyryl Bromide Chemical Properties,Uses,Production

Description

2-Bromoisobutyryl Bromide is a kind of bromide being useful in the chemical industry. It is used as an intermediate for the synthesis of pharmaceuticals, agrochemicals, dyes and other organic chemicals1. It can be used as atom transfer radical polymerization (ATRP) initiator for functionalization of hydroxyl groups present on the surface of graphene oxide; to form an N-protected halodienamide which provided fourand five-membered lactams in the presence of copper (I) and a tertiary amine; in preparation of polycaprolactone macroinitiator via reaction with oligomeric caprolactone dio and mesoporous silica nanoparticles with ATRP initiator anchored on the exterior surface2,3. As a initiator precursor, it can also be used for surface modification of Ethylene-vinyl alcohol (EVOH) copolymer films to grow surface-grafted poly-(acrylamide) chains.

Sources

  1. http://www.chemicalland21.com/specialtychem/finechem/2-BROMOISOBUTYRYL%20BROMIDE.htm
  2. https://www.alfa.com/zh-cn/catalog/B24249/
  3. https://www.sigmaaldrich.com/catalog/product/aldrich/252271?lang=en&region=US
  4. https://pubs.acs.org/doi/abs/10.1021/bk-2003-0854.ch025

Chemical Properties

colourless liquid

Uses

α-Bromoisobutyryl bromide has been used:

  • as atom transfer radical polymerization (ATRP) initiator for functionalization of hydroxyl groups present on the surface of graphene oxide
  • to form an N-protected halodienamide which provided four- and five-membered lactams in the presence of copper (I) and a tertiary amine
  • in preparation of polycaprolactone macroinitiator via reaction with oligomeric caprolactone diol and mesoporous silica nanoparticles with ATRP initiator anchored on the exterior surface

Uses

2-Bromoisobutyryl bromide is used to prepare N-protected halodienamide, which provides four- and five-membered lactams in the presence of copper(I) and a tertiary amine. Further, it is used as atom transfer radical polymerization(ATRP) initiator for functionalization of hydroxyl groups present on the surface of graphene oxide. It is also used in preparation of polycaprolactone macroinitiators through reaction with oligomeric caprolactone diol and mesoporous silica nanoparticles with ATRP initiator anchored on the exterior surface.

2-Bromoisobutyryl Bromide Preparation Products And Raw materials

Raw materials

Preparation Products