Testosterone enanthate
- CAS No.
- 315-37-7
- Chemical Name:
- Testosterone enanthate
- Synonyms
- Enanthate;TESTOSTERONE ENANTATE;Testosterone Enanthat;Testosterone Ethanate;Testosterone enthate;Testo E;Testostroval;Testosterone oenanthate;Testosterone Enanthate 300mg;17-[(1-Oxoheptyl)oxy]androst-4-en-3-one
- CBNumber:
- CB8448727
- Molecular Formula:
- C26H40O3
- Molecular Weight:
- 400.59
- MDL Number:
- MFCD00055890
- MOL File:
- 315-37-7.mol
- MSDS File:
- SDS
| Melting point | 34-39°C |
|---|---|
| alpha | 77 º |
| Boiling point | 463.22°C (rough estimate) |
| Density | 1.0562 (rough estimate) |
| refractive index | 1.4700 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, very soluble in anhydrous ethanol, freely soluble in fatty oils. |
| form | powder |
| color | white to beige |
| InChI | InChI=1/C26H40O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h17,20-23H,4-16H2,1-3H3/t20-,21-,22-,23-,25-,26-/s3 |
| InChIKey | VOCBWIIFXDYGNZ-IXKNJLPQSA-N |
| SMILES | [C@@]12([H])CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])OC(=O)CCCCCC |&1:0,10,12,16,18,21,r| |
| CAS DataBase Reference | 315-37-7(CAS DataBase Reference) |
| FDA UNII | 7Z6522T8N9 |
| Proposition 65 List | Testosterone Enanthate |
| NCI Drug Dictionary | Everone |
| NIST Chemistry Reference | Testosterone enanthate(315-37-7) |
| UNSPSC Code | 12352200 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H350-H361 | |||||||||
| Precautionary statements | P201-P202-P264-P270-P301+P312-P308+P313 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 45-63 | |||||||||
| Safety Statements | 53-22-36/37/39-45 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XA3080000 | |||||||||
| HS Code | 2937290000 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 4 Oral Carc. 1B Repr. 2 |
|||||||||
| Toxicity | man,TDLo,intramuscular,7519mg/kg/5W- (7519mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEA,New England Journal of Medicine. Vol. 308, Pg. 508, 1983. | |||||||||
| NFPA 704 |
|
Testosterone enanthate price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001317 | Testosterone enantate for system suitability European Pharmacopoeia (EP) Reference Standard | 315-37-7 | 2 mg | $127 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0001312 | Testosterone enantate for peak identification European Pharmacopoeia (EP) Reference Standard | 315-37-7 | 10 mg | $164 | 2026-04-30 | Buy |
| Sigma-Aldrich | T3006 | Testosterone enanthate analytical standard | 315-37-7 | 1g | $119 | 2026-04-30 | Buy |
| Sigma-Aldrich | T0250000 | Testosterone enantate European Pharmacopoeia (EP) Reference Standard | 315-37-7 | 40 mg | $167 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1648004 | Testosterone enanthate United States Pharmacopeia (USP) Reference Standard | 315-37-7 | 200mg | $611 | 2026-04-30 | Buy |
Testosterone enanthate Chemical Properties, Uses, Production
Indications and Usage
Testosterone enanthate is a type of androgen drug, and it is a synthetic compound of testosterone proprionate and testosterone enantate. Its effects are the same as those of testosterone acetate, which include promoting the development of male sex organs and secondary sex characteristics and resisting estrogen. It also has protein assimilating effects, which allow it to help muscle growth and weight gain. Testosterone enanthate can inhibit the pituitary gland and promote sex hormone secretion, thus decreasing the endogenous testosterone secreted by Leydig cells, which achieves the purpose of stopping spermatogenesis.
Testosterone enanthate can be used as a long-term male birth control drug. It is clinically used to treat male hypogonadism and gonadal insufficiency, sex organ hypogenesis, infertility, eunuchism, and cryptorchidism. It can also be used to treat female dysfunctional uterine bleeding, menopausal syndrome, breast cancer and uterine cancer. It can also treat cirrhosis, aplastic anemia, osteoporosis and other consumptive diseases.
Drug Metabolism
After injection, it creates a blood concentration higher than the physiological level, and then blood concentration decreases rapidly.
Clinical Research
In a trial that injected monkeys with testosterone enanthate every week, the monkeys’ sperm cells began experiencing apoptosis in a week, with apoptosis rates peaking in the fifth week. A clinical trial with 308 participants also showed that testosterone enanthate’s birth-control effects are much more effective on Asian men than on Caucasian men, as over 95% of Asian men achieved azoospermia, while only 40-70% of Caucasian men did.
A trial of over 100 volunteers showed that weekly muscle injections of 250mg led to most men developing azoospermia or severe ogliospermia in 10 weeks, and that sperm count could recover after ceasing injection for a certain period of time. If the injection intervals are extended to over 10-12 days, even increasing dosage will not have desired effects. Testosterone enanthate only needs to be injected once a week, which is an advantage over testosterone acetate.
Adverse reactions
Large dosages or extended use can cause water and sodium retention and edema. Young women may exhibit virilism, with characteristics including deepened voice, hair growth, acne, clitoral hypertrophy, etc. Not to be used by patients with prostatic cancer or pregnant patients. Should be used with caution by patients with prostate hypertrophy and liver and kidney dysfunction. When treating breast cancer, drug usage should be stopped immediately if hypercalcemia is detected.
Description
Testosterone enanthate (Item No. 22546) is an analytical reference standard categorized as an anabolic androgenic steroid. It is an ester of the naturally occurring androgen, testosterone (Item Nos. 15645 | ISO60154) with a longer half-life. Formulations containing testosterone enanthate have been tested for use in hypogonadism and as a potential male contraceptive. Formulations containing it have been associated with higher levels of total cholesterol, low density lipoproteins, and triglycerides and lower levels of high density lipoproteins. Anabolic steroids, including testosterone enanthate, have been used to enhance physical performance in racehorses and athletes, and methods to detect steroids, their derivatives, and their metabolites have been developed. This product is intended for research and forensic applications.
Chemical Properties
White or yellowish-white, crystalline powder.
Originator
Delatestryl,Squibb,US,1954
Uses
Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.
Definition
ChEBI: Testosterone enanthate is a heptanoate ester and a sterol ester. It has a role as an androgen. It is functionally related to a testosterone.
Manufacturing Process
A mixture of testosterone, pyridine and oenanthic acid anhydride is heated for 1 1/2 hours to 125°C. The cooled reaction mixture is decomposed with water while stirring and cooling. After prolonged standing at a temperature below room temperature, the whole is extracted with ether and the ethereal solution is washed consecutively with dilute sulfuric acid, water, 5% sodium hydroxide solution, and again with water. The crude ester remaining on evaporation of the dried ether solution, after recrystallization from pentane, melts at 36° to 37.5°C.
Therapeutic Function
Androgen
References
[1] BEHRE H, NIESCHLAG E. Testosterone: Testosterone preparations for clinical use in males[C]. 2012: 0. DOI: 10.1017/cbo9781139003353.016
[2] LOUIS DEHENNIN Alvin M M. Long-term administration of testosterone enanthate to normal men: Alterations of the urinary profile of androgen metabolites potentially useful for detection of testosterone misuse in sport[J]. Journal of Steroid Biochemistry and Molecular Biology, 1993, 44 2: Pages 179-189. DOI: 10.1016/0960-0760(93)90026-s
[3] F C WU. Oral progestogen combined with testosterone as a potential male contraceptive: additive effects between desogestrel and testosterone enanthate in suppression of spermatogenesis, pituitary-testicular axis, and lipid metabolism.[J]. Journal of Clinical Endocrinology & Metabolism, 1999, 84 1: 112-122. DOI: 10.1210/jcem.84.1.5412
[4] FRIEDRICH JOCKENHVEL . Influence of various modes of androgen substitution on serum lipids and lipoproteins in hypogonadal men[J]. Metabolism: clinical and experimental, 1999, 48 5: Pages 590-596. DOI: 10.1016/s0026-0495(99)90056-2
[5] YOUWEN YOU. Simultaneous separation and determination of 16 testosterone and nandrolone esters in equine plasma using ultra high performance liquid chromatography-tandem mass spectrometry for doping control.[J]. Journal of Chromatography A, 2011, 1218 26: 3982-3993. DOI: 10.1016/j.chroma.2011.04.087
Testosterone enanthate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Proisen BiomedicalCoLtd | 19098059326 | 3522706365@qq.com | China | 33 | 58 |
| Hubei Jiayuan Biotechnology Co., Ltd. | 13388043236 | 3775121585@qq.com | China | 2 | 58 |
| Shandong Baixinchangda Biotechnology Co., Ltd | 19229895729 19229895729 | China | 32 | 58 | |
| ZheJangYouNingBiotechology.co.,LTD | 15557595058 | China | 24 | 58 | |
| Nanjing Ujijing Biotechnology Co., Ltd. | 17751427757 17751427757 | 1562906574@qq.com | China | 18 | 58 |
| Guangdong Taibo Pharmaceutical Technology Co., Ltd. | 15557595058 15557595058 | 3954090990@QQ.COM | China | 13 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
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View Latest Price from Testosterone enanthate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-16 | Testosterone enanthate
315-37-7
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$1.00 | 1KG | 99.9% | 500KG | .GZ HONESTCHEM CO.,LTD | |
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2026-09-16 | Atlates | $1.00 | 1KG | 99.9% | 500KG | .GZ HONESTCHEM CO.,LTD | |
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2026-09-16 | Atlatest | $1.00 | 1KG | 99.9% | 500KG | .GZ HONESTCHEM CO.,LTD |
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