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Testosterone enanthate

CAS No.
315-37-7
Chemical Name:
Testosterone enanthate
Synonyms
Enanthate;TESTOSTERONE ENANTATE;Testosterone Enanthat;Testosterone Ethanate;Testostroval;Testosterone oenanthate;17-[(1-Oxoheptyl)oxy]androst-4-en-3-one;Testosterone Enanthate (Test e ,TE)-1 gram(2);Factory hot selling Testosterone Enanthate cas315-37-7 CAS NO.315-37-7;Everone
CBNumber:
CB8448727
Molecular Formula:
C26H40O3
Molecular Weight:
400.59
MDL Number:
MFCD00055890
MOL File:
315-37-7.mol
MSDS File:
SDS
Last updated:2025-08-20 16:56:25
Product description Number Pack Size Price
Testosterone enantate for system suitability European Pharmacopoeia (EP) Reference Standard Y0001317 2 mg $118
Testosterone enantate for peak identification European Pharmacopoeia (EP) Reference Standard Y0001312 10 mg $153
Testosterone enanthate analytical standard T3006 1g $113
Testosterone enantate European Pharmacopoeia (EP) Reference Standard T0250000 40 mg $156
Testosterone enanthate United States Pharmacopeia (USP) Reference Standard 1648004 200mg $569
More product size

Testosterone enanthate Properties

Melting point 34-39°C
alpha 77 º
Boiling point 463.22°C (rough estimate)
Density 1.0562 (rough estimate)
refractive index 1.4700 (estimate)
storage temp. 2-8°C
solubility Practically insoluble in water, very soluble in anhydrous ethanol, freely soluble in fatty oils.
form powder
color white to beige
InChI InChI=1/C26H40O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h17,20-23H,4-16H2,1-3H3/t20-,21-,22-,23-,25-,26-/s3
InChIKey VOCBWIIFXDYGNZ-IXKNJLPQSA-N
SMILES [C@@]12([H])CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])OC(=O)CCCCCC |&1:0,10,12,16,18,21,r|
CAS DataBase Reference 315-37-7(CAS DataBase Reference)
FDA UNII 7Z6522T8N9
Proposition 65 List Testosterone Enanthate
NCI Drug Dictionary Everone
NIST Chemistry Reference Testosterone enanthate(315-37-7)
UNSPSC Code 12352200
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H350-H361
Precautionary statements  P201-P202-P264-P270-P301+P312-P308+P313
Hazard Codes  T
Risk Statements  45-63
Safety Statements  53-22-36/37/39-45
WGK Germany  3
RTECS  XA3080000
HS Code  2937290000
Toxicity man,TDLo,intramuscular,7519mg/kg/5W- (7519mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEA,New England Journal of Medicine. Vol. 308, Pg. 508, 1983.
NFPA 704
0
3 0

Testosterone enanthate price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001317 Testosterone enantate for system suitability European Pharmacopoeia (EP) Reference Standard 315-37-7 2 mg $118 2025-07-31 Buy
Sigma-Aldrich Y0001312 Testosterone enantate for peak identification European Pharmacopoeia (EP) Reference Standard 315-37-7 10 mg $153 2025-07-31 Buy
Sigma-Aldrich T3006 Testosterone enanthate analytical standard 315-37-7 1g $113 2025-07-31 Buy
Sigma-Aldrich T0250000 Testosterone enantate European Pharmacopoeia (EP) Reference Standard 315-37-7 40 mg $156 2025-07-31 Buy
Sigma-Aldrich 1648004 Testosterone enanthate United States Pharmacopeia (USP) Reference Standard 315-37-7 200mg $569 2025-07-31 Buy
Product number Packaging Price Buy
Y0001317 2 mg $118 Buy
Y0001312 10 mg $153 Buy
T3006 1g $113 Buy
T0250000 40 mg $156 Buy
1648004 200mg $569 Buy

Testosterone enanthate Chemical Properties,Uses,Production

Indications and Usage

Testosterone enanthate is a type of androgen drug, and it is a synthetic compound of testosterone proprionate and testosterone enantate. Its effects are the same as those of testosterone acetate, which include promoting the development of male sex organs and secondary sex characteristics and resisting estrogen. It also has protein assimilating effects, which allow it to help muscle growth and weight gain. Testosterone enanthate can inhibit the pituitary gland and promote sex hormone secretion, thus decreasing the endogenous testosterone secreted by Leydig cells, which achieves the purpose of stopping spermatogenesis.
Testosterone enanthate can be used as a long-term male birth control drug. It is clinically used to treat male hypogonadism and gonadal insufficiency, sex organ hypogenesis, infertility, eunuchism, and cryptorchidism. It can also be used to treat female dysfunctional uterine bleeding, menopausal syndrome, breast cancer and uterine cancer. It can also treat cirrhosis, aplastic anemia, osteoporosis and other consumptive diseases.

Drug Metabolism

After injection, it creates a blood concentration higher than the physiological level, and then blood concentration decreases rapidly.

Clinical Research

In a trial that injected monkeys with testosterone enanthate every week, the monkeys’ sperm cells began experiencing apoptosis in a week, with apoptosis rates peaking in the fifth week. A clinical trial with 308 participants also showed that testosterone enanthate’s birth-control effects are much more effective on Asian men than on Caucasian men, as over 95% of Asian men achieved azoospermia, while only 40-70% of Caucasian men did.
A trial of over 100 volunteers showed that weekly muscle injections of 250mg led to most men developing azoospermia or severe ogliospermia in 10 weeks, and that sperm count could recover after ceasing injection for a certain period of time. If the injection intervals are extended to over 10-12 days, even increasing dosage will not have desired effects. Testosterone enanthate only needs to be injected once a week, which is an advantage over testosterone acetate.

Adverse reactions

Large dosages or extended use can cause water and sodium retention and edema. Young women may exhibit virilism, with characteristics including deepened voice, hair growth, acne, clitoral hypertrophy, etc. Not to be used by patients with prostatic cancer or pregnant patients. Should be used with caution by patients with prostate hypertrophy and liver and kidney dysfunction. When treating breast cancer, drug usage should be stopped immediately if hypercalcemia is detected.

Description

Testosterone enanthate (Item No. 22546) is an analytical reference standard categorized as an anabolic androgenic steroid. It is an ester of the naturally occurring androgen, testosterone (Item Nos. 15645 | ISO60154) with a longer half-life. Formulations containing testosterone enanthate have been tested for use in hypogonadism and as a potential male contraceptive. Formulations containing it have been associated with higher levels of total cholesterol, low density lipoproteins, and triglycerides and lower levels of high density lipoproteins. Anabolic steroids, including testosterone enanthate, have been used to enhance physical performance in racehorses and athletes, and methods to detect steroids, their derivatives, and their metabolites have been developed. This product is intended for research and forensic applications.

Chemical Properties

White or yellowish-white, crystalline powder.

Originator

Delatestryl,Squibb,US,1954

Uses

Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.

Definition

ChEBI: Testosterone enanthate is a heptanoate ester and a sterol ester. It has a role as an androgen. It is functionally related to a testosterone.

Manufacturing Process

A mixture of testosterone, pyridine and oenanthic acid anhydride is heated for 1 1/2 hours to 125°C. The cooled reaction mixture is decomposed with water while stirring and cooling. After prolonged standing at a temperature below room temperature, the whole is extracted with ether and the ethereal solution is washed consecutively with dilute sulfuric acid, water, 5% sodium hydroxide solution, and again with water. The crude ester remaining on evaporation of the dried ether solution, after recrystallization from pentane, melts at 36° to 37.5°C.

Therapeutic Function

Androgen

References

[1] BEHRE H, NIESCHLAG E. Testosterone: Testosterone preparations for clinical use in males[C]. 2012: 0. DOI: 10.1017/cbo9781139003353.016
[2] LOUIS DEHENNIN  Alvin M M. Long-term administration of testosterone enanthate to normal men: Alterations of the urinary profile of androgen metabolites potentially useful for detection of testosterone misuse in sport[J]. Journal of Steroid Biochemistry and Molecular Biology, 1993, 44 2: Pages 179-189. DOI: 10.1016/0960-0760(93)90026-s
[3] F C WU. Oral progestogen combined with testosterone as a potential male contraceptive: additive effects between desogestrel and testosterone enanthate in suppression of spermatogenesis, pituitary-testicular axis, and lipid metabolism.[J]. Journal of Clinical Endocrinology & Metabolism, 1999, 84 1: 112-122. DOI: 10.1210/jcem.84.1.5412
[4] FRIEDRICH JOCKENH?VEL . Influence of various modes of androgen substitution on serum lipids and lipoproteins in hypogonadal men[J]. Metabolism: clinical and experimental, 1999, 48 5: Pages 590-596. DOI: 10.1016/s0026-0495(99)90056-2
[5] YOUWEN YOU. Simultaneous separation and determination of 16 testosterone and nandrolone esters in equine plasma using ultra high performance liquid chromatography-tandem mass spectrometry for doping control.[J]. Journal of Chromatography A, 2011, 1218 26: 3982-3993. DOI: 10.1016/j.chroma.2011.04.087

111-14-8
26614-48-2
315-37-7
Synthesis of Testosterone enanthate from Heptanoic acid and 3-Ethoxyandrosta-3,5-dien-17β-ol

Testosterone enanthate Preparation Products And Raw materials

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315-37-7
US $1.00 / KG 1KG 99.9% 500KG .GZ HONESTCHEM CO.,LTD
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Testosterone enanthate Spectrum

17-Hydroxyandrost-4-en-3-one, 17-heptanoate 3-Oxoandrost-4-en-17-yl heptanoate Andro L.A. 200 Androst-4-en-3-one, 17-[(1-oxoheptyl)oxy]-, (17beta)- Androst-4-en-3-one, 17beta-hydroxy-, heptanoate Androtardyl Atlatest component of Androgyn l.a. component of Deladumone component of Ditate component of Mal-O-Fem L.A Delatest Depo-Testro Med Everone Exten test Heptanoic acid, ester with testosterone heptanoicacid,esterwithtestosterone Malogen L.A. Malogen L.A.200 malogenl.a.200 NSC-17591 Orquisteron-E reposotmd Reposo-TMD Testanthate Testate testenate TESTOSTERONEENANTHATE,USP [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate 17b-Enanthoxyandrost-4-en-3-one 17b-Hydroxyandrost-4-en-3-one enanthate 4-Androsten-3-one 17b-enanthate Androst-4-en-3-one, 17-[(1-oxoheptyl)oxy]-, (17b)- (9CI) Primoteston-Depot Testosterone, heptanoate (6CI, 8CI) Testosterone Enanthate Injection 4-Androsten-17β-ol-3-one 17-enanthate Testosterone 17β-heptanoate Testosterone Enanthate CIII (200 mg) Testosterone Enanthate (CIII), BP, EP Testosterone Heptanoate-d5 Testosterone-d3 Heptanoate 17β-Hydroxy-4-androsten-3-one 17-enanthate, 4-Androsten-17β-ol-3-one 17-enanthate, Testosterone 17β-heptanoate 17β-(Heptanoyloxy)androst-4-en-3-one 3-Oxoandrost-4-en-17β-ol heptanoate Enanthic acid testosterone Atlates enanthic acid [(8R,9S,10R,13S,14S,17S)-3-keto-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] ester (8R,9S,10R,13S,14S,17S)-10,13-diMethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl heptanoate Androst-4-en-3-one,17-[(1-oxoheptyl)oxy]-, (17b)- Testosterone enanthate Testosterone heptanoate Testosterone enantate for system suitability Testosterone enantate for peak identification Androst-4-en-3-one, 17-[(1-oxoheptyl)oxy]-, (17β)- -10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl heptanoate Testosterone enthate Testinon Testoenant