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3-keto Sphinganine (d12:0) (hydrochloride)
- CAS No.
- 1823032-02-5
- Chemical Name:
- 3-keto Sphinganine (d12:0) (hydrochloride)
- Synonyms
- 3-keto-C12-Dihydrosphingosine HCl salt;3-keto Sphinganine (d12:0) (hydrochloride);2-amino-1-hydroxy-3-dodecanone,monohydrochloride
- CBNumber:
- CB84665720
- Molecular Formula:
- C12H26ClNO2
- Molecular Weight:
- 251.8
- MDL Number:
- MFCD24672582
- MOL File:
- 1823032-02-5.mol
Last updated:2023-04-23 13:52:06
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3-keto Sphinganine (d12:0) (hydrochloride) Chemical Properties,Uses,Production
Description
3-keto Sphinganine (d12:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0) . 3-keto Sphinganine (d18:0) is a lyso-sphingolipid formed by the condensation of L-serine and palmitoyl-CoA by serine palmitoyl transferase (SPT). Vitamin K deficiency inactivates SPT resulting in a decrease in the production of 3-keto sphinganine and other sphingolipids.1
References
1. Batheja, A.D., Uhlinger, D.J., Carton, J.M., et al. Characterization of serine palmitoyltransferase in normal human tissues J. Histochem. Cytochem. 51(5),687-696(2003).
3-keto Sphinganine (d12:0) (hydrochloride) Preparation Products And Raw materials
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3-keto Sphinganine (d12:0) (hydrochloride)
3-keto-C12-Dihydrosphingosine HCl salt
2-amino-1-hydroxy-3-dodecanone,monohydrochloride
1823032-02-5