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CCG-232601

CCG-232601 structure

CAS No.: 1922099-21-5

Chemical Name:: CCG-232601

Synonyms: CCG-232601;CCG-232601 (CCG232601);N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide;3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-

CBNumber:: CB84665922

Molecular Formula:: C24H20ClF2N3O2

Molecular Weight:: 455.88

MDL Number:: MFCD31812420

MOL File:: 1922099-21-5.mol

Last updated:2023-05-21 10:59:17

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CCG-232601 Properties

Boiling point	683.1±55.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form	A crystalline solid
pka	13.69±0.70(Predicted)

CCG-232601 price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	24382	CCG-232601 ≥98%	1922099-21-5	1mg	$109	2024-03-01	Buy
Cayman Chemical	24382	CCG-232601 ≥98%	1922099-21-5	5mg	$481	2024-03-01	Buy
AK Scientific	5832EG	N-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide	1922099-21-5	5mg	$617	2021-12-16	Buy
Axon Medchem	Axon2753	CCG232601 99%	1922099-21-5	5mg	$176	2021-12-16	Buy
AK Scientific	5832EG	N-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide	1922099-21-5	1mg	$214	2021-12-16	Buy

Product number	Packaging	Price	Buy
24382	1mg	$109	Buy
24382	5mg	$481	Buy
5832EG	5mg	$617	Buy
Axon2753	5mg	$176	Buy
5832EG	1mg	$214	Buy

CCG-232601 Chemical Properties,Uses,Production

Description

CCG-232601 is an inhibitor of the Rho/MRTF/SRF transcriptional pathway and a derivative of CCG-203971 . CCG-232601 inhibits MRTF-dependent transcription in HEK293T cells (IC₅₀ = 0.55 μM in a luciferase reporter assay). It also reduces expression of α-smooth muscle actin (α-SMA) in TGF-β-stimulated human dermal fibroblasts to 31% of control when used at a concentration of 10 μM. CCG-232601 (50 mg/kg) inhibits increases in dermal thickness and hydroxyproline content in a mouse model of dermal fibrosis induced by bleomycin .

CCG-232601 Preparation Products And Raw materials

Raw materials

Preparation Products

CCG-232601 Suppliers

Global( 10)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9707	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd	15317229551	15151849396@163.com	China	996	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	5584	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9268	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
BOC Sciences	65
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd	58
Nanjing Tengyi Biotechnology Co., Ltd	58
RD International Technology Co., Limited	58

CCG-232601 CCG-232601 (CCG232601) 3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]- N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide 1922099-21-5