ChemicalBook >> CAS DataBase List >>CCG-232601

CCG-232601

CAS No.
1922099-21-5
Chemical Name:
CCG-232601
Synonyms
CCG-232601;CCG-232601 (CCG232601);N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide;3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-
CBNumber:
CB84665922
Molecular Formula:
C24H20ClF2N3O2
Molecular Weight:
455.88
MDL Number:
MFCD31812420
MOL File:
1922099-21-5.mol
Last updated:2023-05-21 10:59:17

CCG-232601 Properties

Boiling point 683.1±55.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form A crystalline solid
pka 13.69±0.70(Predicted)

CCG-232601 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24382 CCG-232601 ≥98% 1922099-21-5 1mg $109 2024-03-01 Buy
Cayman Chemical 24382 CCG-232601 ≥98% 1922099-21-5 5mg $481 2024-03-01 Buy
AK Scientific 5832EG N-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide 1922099-21-5 5mg $617 2021-12-16 Buy
Axon Medchem Axon2753 CCG232601 99% 1922099-21-5 5mg $176 2021-12-16 Buy
AK Scientific 5832EG N-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide 1922099-21-5 1mg $214 2021-12-16 Buy
Product number Packaging Price Buy
24382 1mg $109 Buy
24382 5mg $481 Buy
5832EG 5mg $617 Buy
Axon2753 5mg $176 Buy
5832EG 1mg $214 Buy

CCG-232601 Chemical Properties,Uses,Production

Description

CCG-232601 is an inhibitor of the Rho/MRTF/SRF transcriptional pathway and a derivative of CCG-203971 . CCG-232601 inhibits MRTF-dependent transcription in HEK293T cells (IC50 = 0.55 μM in a luciferase reporter assay). It also reduces expression of α-smooth muscle actin (α-SMA) in TGF-β-stimulated human dermal fibroblasts to 31% of control when used at a concentration of 10 μM. CCG-232601 (50 mg/kg) inhibits increases in dermal thickness and hydroxyproline content in a mouse model of dermal fibrosis induced by bleomycin .

CCG-232601 Preparation Products And Raw materials

Raw materials

Preparation Products

CCG-232601 Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 995 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 23980 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5584 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9268 58
CCG-232601 CCG-232601 (CCG232601) 3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]- N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide 1922099-21-5