C18 Ceramide-d3 (d18:1/18:0-d3)
- CAS No.
- 2011762-82-4
- Chemical Name:
- C18 Ceramide-d3 (d18:1/18:0-d3)
- Synonyms
- C18 Ceramide-d3 (d18:1/18:0-d3);N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl-d3]-octadecanamide
- CBNumber:
- CB84666080
- Molecular Formula:
- C36H71NO3
- Molecular Weight:
- 565.97
- MDL Number:
- MFCD33024355
- MOL File:
- 2011762-82-4.mol
C18 Ceramide-d3 (d18:1/18:0-d3) price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 24396 | C18 Ceramide-d3 (d18:1/18:0-d3) ≥99% deuterated forms (d1-d3); ≤1% d0 | 2011762-82-4 | 1mg | $426 | 2024-03-01 | Buy |
AK Scientific | 1487EN | 18,18,18-Trideuterio-N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]octadecanamide | 2011762-82-4 | 1mg | $826 | 2021-12-16 | Buy |
C18 Ceramide-d3 (d18:1/18:0-d3) Chemical Properties,Uses,Production
Biological Activity
C18 Ceramide-d3 (d18:1/18:0) is intended for use as an internal standard for the quantification of C18 Ceramide (d18:1/18:0) by GC- or LC-MS. C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice.1 Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells.2 It is selectively downregulated in 32 human head and neck squamous cell carcinoma tumor tissues as compared to non-squamous tumor tissues. C18 Ceramide concentration is significantly higher in muscle tissue of type 2 diabetic patients compared with non-diabetic patients and is positively correlated to body mass index and inversely related to insulin sensitivity.3 [Matreya, LLC. Catalog No. 2201]
References
1.Mizutani, Y., Kihara, A., and Igarashi, Y.Mammalian Lass6 and its related family members regulate synthesis of specific ceramidesBiochem J.390(Pt. 1)263-271(2005) 2.Koybasi, S., Senkal, C.E., Sundararaj, K., et al.Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomasJ. Biol. Chem.279(43)44311-44319(2004) 3.Bergman, B.C., Brozinick, J.T., Strauss, A., et al.Muscle sphingolipids during rest and exercise: A C18:0 signature for insulin resistance in humansDiabetologia59(3)785-791(2016)
C18 Ceramide-d3 (d18:1/18:0-d3) Preparation Products And Raw materials
Raw materials
Preparation Products
C18 Ceramide-d3 (d18:1/18:0-d3) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1976 | 58 |
Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
Supplier | Advantage |
---|---|
Alfa Chemistry | 58 |
Yichang Zhongyitai Trading Co., Ltd. | 58 |
Alfa Chemistry | 60 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 58 |