ChemicalBook >> CAS DataBase List >>LJ570
LJ570
- CAS No.
- 2252488-69-8
- Chemical Name:
- LJ570
- Synonyms
- LJ570;1,1'-Biphenyl]-4-propanoic acid,α-([1,1'-biphenyl]-4-yloxy)-,(αS)-;[1,1'-Biphenyl]-4-propanoic acid, α-([1,1'-biphenyl]-4-yloxy)-, (αS)-;(2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-{[1,1'-biphenyl]-4-yl}propanoic acid;inhibit,Peroxisome proliferator-activated receptors,LJ-570,LJ 570,LJ570,Inhibitor,PPAR
- CBNumber:
- CB84676593
- Molecular Formula:
- C27H22O3
- Molecular Weight:
- 394.47
- MDL Number:
- MFCD32062685
- MOL File:
- 2252488-69-8.mol
Last updated:2023-09-20 16:43:00
LJ570 Chemical Properties,Uses,Production
Description
LJ570 is the first PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation. LJ570 is a potent partial agonist of both PPARα and γ subtypes. LJ570 inhibited the Cdk5-mediated phosphorylation of PPARγ at serine 273 that is currently considered the mechanism by which some PPARγ partial agonists exert antidiabetic effects similar to thiazolidinediones, without showing their typical side effects. LJ570 may be useful for treatment of dyslipidemic type 2 diabetes.
target
LJ570 is the first PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation.
LJ570 Preparation Products And Raw materials
Raw materials
Preparation Products
LJ570 Suppliers
Global( 24)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5225 | 58 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4334 | 55 | |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9945 | 58 |
Shanghai SuperLan Chemcial Technique Centre | 021-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9082 | 58 |
Chuzhou KeMail Chemical Technology Co., Ltd | 0550-5196001 15000891977 | wj520wjxby@126.com | China | 1841 | 55 |
JinJin Le Chemical Co., Ltd | 10106090 | jjlchem2@163.com | China | 9981 | 58 |
LJ570
[1,1'-Biphenyl]-4-propanoic acid, α-([1,1'-biphenyl]-4-yloxy)-, (αS)-
1,1'-Biphenyl]-4-propanoic acid,α-([1,1'-biphenyl]-4-yloxy)-,(αS)-
inhibit,Peroxisome proliferator-activated receptors,LJ-570,LJ 570,LJ570,Inhibitor,PPAR
(2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-{[1,1'-biphenyl]-4-yl}propanoic acid
2252488-69-8