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N-Methylphthalimide

CAS No.
550-44-7
Chemical Name:
N-Methylphthalimide
Synonyms
2-Methylisoindoline-1,3-dione;T56 BVNVJ C1;METHYL PHTHALIMIDE;N-METHYLPHTHALIMIDE;n-methyl-phthalimid;PHTHALIMIDE-N-METHYL;N-Methylphthalimide>2-Methyl-1H-isoindole-1;N-Methylphthalimide,98%;Rivaroxaban Impurity 20
CBNumber:
CB8473039
Molecular Formula:
C9H7NO2
Molecular Weight:
161.16
MDL Number:
MFCD00023063
MOL File:
550-44-7.mol
MSDS File:
SDS
Last updated:2023-04-27 16:27:43

N-Methylphthalimide Properties

Melting point 129-132 °C (lit.)
Boiling point 286.05°C
Density 1.2443 (rough estimate)
refractive index 1.4500 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka -2.09±0.20(Predicted)
color White to Off-White
BRN 124428
CAS DataBase Reference 550-44-7(CAS DataBase Reference)
FDA UNII 647UP45J2U
NIST Chemistry Reference 1H-Isoindole-1,3(2H)-dione, 2-methyl-(550-44-7)
EPA Substance Registry System 1H-Isoindole-1,3(2H)-dione, 2-methyl- (550-44-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  1
RTECS  TI5602700
TSCA  Yes
HazardClass  IRRITANT
HS Code  29251900
NFPA 704
1
2 0

N-Methylphthalimide price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 407992 N-Methylphthalimide 98% 550-44-7 5g $41.2 2024-03-01 Buy
TCI Chemical M0299 N-Methylphthalimide >99.0%(GC) 550-44-7 25g $66 2024-03-01 Buy
Alfa Aesar L08991 N-Methylphthalimide, 98% 550-44-7 25g $70.65 2024-03-01 Buy
Alfa Aesar L08991 N-Methylphthalimide, 98% 550-44-7 5g $20.8 2021-12-16 Buy
TRC M314360 2-Methylisoindole-1,3-dione 550-44-7 100g $155 2021-12-16 Buy
Product number Packaging Price Buy
407992 5g $41.2 Buy
M0299 25g $66 Buy
L08991 25g $70.65 Buy
L08991 5g $20.8 Buy
M314360 100g $155 Buy

N-Methylphthalimide Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene h and the selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one have been studied.

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 497, 1979 DOI: 10.1021/jo01318a005

General Description

Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene has been studied. The selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one in ionic liquids and phenol as a proton donor under silent and ultrasonic conditions has been reported. Single electron transfer (SET)-induced photochemical reaction of NMP with silyl enol ether has been investigated. Nitration of NMP is reported to afford “exclusively” 3-nitro-derivative.

Purification Methods

Recrystallise the imide from absolute EtOH or AcOH (m 134o). The IR has max at 1780 and 1380cm -1. [Beilstein 21 H 461, 21 III/IV 5030.]

85-41-6
431-47-0
550-44-7
Synthesis of N-Methylphthalimide from Phthalimide and Methyl trifluoroacetate

N-Methylphthalimide Preparation Products And Raw materials

Global( 335)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Kaitian Chemical Co., LTD
+undefined13337835376 kt_chem@126.com China 40 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10297 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12321 58

View Lastest Price from N-Methylphthalimide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-methylphthalimide pictures 2023-04-11 N-methylphthalimide
550-44-7
US $0.00-0.00 / kg 1kg 98% 500 tons Nanjing Kaitian Chemical Co., LTD
T56 BVNVJ C1 pictures 2022-02-25 T56 BVNVJ C1
550-44-7
US $19.00 / KG 1KG 99% 16tons Hong Kong Tiansheng New Material Trading Co., Ltd
N-Methylphthalimide pictures 2021-07-13 N-Methylphthalimide
550-44-7
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • T56 BVNVJ C1 pictures
  • T56 BVNVJ C1
    550-44-7
  • US $19.00 / KG
  • 99%
  • Hong Kong Tiansheng New Material Trading Co., Ltd
  • N-Methylphthalimide pictures
  • N-Methylphthalimide
    550-44-7
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
2-Methyl-1H-isoindole-1 Rivaroxaban Impurity F ( N-Methyl Phthalimide ) CAS No. 550-44-7 Imp. F:N-Methylphthalimide Rivaroxaban impurity P1-B 1H-Isoindole-1,3(2H)-dione,2-methyl- 2-Methyl-1H-isoindol-1,3(2H)-dion 2-methyl-1h-isoindole-3(2h)-dione 2-Methyl-isoindole-1,3-dione n-methyl-phthalimid N-METHYLPHTHALIMIDE PHTHALIMIDE-N-METHYL 2-METHYL-1H-ISOINDOLE-1,3(2H)-DIONE METHYL PHTHALIMIDE N-Methylphthalimide,98% n-methyl-1h-isoindole-1,3-(2h)-dione Rivaroxaban N-Methylphthalimide Impurity Rivaroxaban Impurity F ( N-Methyl Phthalimide ) Rivaroxaban Impurity 20 Rivaroxaban related mixture 1 (N-methyl collar phthalimide) N-Methylphthalimide> Rivaroxaban Impurity F/ Rivaroxaban N-Methylphthalimide Impurity T56 BVNVJ C1 2-Methylisoindoline-1,3-dione Rivaroxaban Impurity 99 (N-Methyl Phthalimide) 550-44-7 Carbonyl Compounds Building Blocks Cyclic Imides Organic Building Blocks N-Substituted Maleimides, Succinimides & Phthalimides N-Substituted Phthalimides intermediates N-Substituted Maleimides, Succinimides & Phthalimides N-Substituted Phthalimides Cyclic ImidesDerivatization Reagents Carbonyl Compounds Derivatization Reagents HPLC Organic Building Blocks UV-VIS API intermediates