APOLIPOPROTEIN A-I, HUMAN
- CAS No.
- Chemical Name:
- APOLIPOPROTEIN A-I, HUMAN
- Synonyms
- APO A-1;APO A-I;C117399;MGC117399;HUMAN APOA-I;APO-A1, HUMAN;APO A-I, HUMAN;ApoA-1 from rat;APOLIPROTEIN A-I;APOLIPOPROTEIN AI
- CBNumber:
- CB8474566
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00132610
- MOL File:
- Mol file
| storage temp. | −20°C |
|---|---|
| solubility | H2O: 1 mg/mL, clear, colorless |
| form | solution (clear) |
| color | colorless |
| FDA UNII | 7YRL85VVH1 |
APOLIPOPROTEIN A-I, HUMAN price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB2502171 | Anti-APOA1 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 100μG | $568 | 2024-03-01 | Buy | |
| Sigma-Aldrich | 178452 | Apolipoprotein A-I, Human Plasma, High-Density Lipoprotein Native apolipoprotein A-I from human plasma. Functions as a cofactor for lecithin-cholesterol acyltransferase. A component of high density lipoprotein. | 500μg | $247 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SRP4693 | Apolipoprotein A−I human recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC) | 1426185-50-3 | 100μG | $345 | 2023-06-20 | Buy |
| Usbiological | A2299-10F | Apolipoprotein A-I, Human | 500ug | $375 | 2021-12-16 | Buy | |
| Usbiological | 139298 | Apolipoprotein AI | 200ul | $438 | 2021-12-16 | Buy |
APOLIPOPROTEIN A-I, HUMAN Chemical Properties,Uses,Production
Uses
Apolipoprotein A-I human has been used in the cholesterol efflux assay.
General Description
ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol." The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
Biochem/physiol Actions
ApoA-I (apolipoprotein A-I), which is found exclusively in HDL (high-density lipoprotein), has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is thought to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol." The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases. Changes in the level of serum apoA-I may serve as a prognostic marker for non-metastatic nasopharyngeal carcinoma. Low levels of apoA-I in the plasma is linked to hyperhomocysteinemia.
APOLIPOPROTEIN A-I, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
APOLIPOPROTEIN A-I, HUMAN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Sig Biotechnology Co., LTD | 021-57810052 18930344717 | 2089316240@qq.com | China | 9396 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 15926423062 | 422450190@qq.com | China | 10132 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 6633 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |