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Enoxolone

Enoxolone
Enoxolone structure
CAS No.
471-53-4
Chemical Name:
Enoxolone
Synonyms
PO 12;GM 1658;STX 352;18 BETA;biosone;ENOXOLONE;ENOLOXONE;NSC 35347;Arthrodont;glycyrrhetin
CBNumber:
CB8474793
Molecular Formula:
C30H46O4
Formula Weight:
470.68
MOL File:
471-53-4.mol

Enoxolone Properties

Melting point:
292-295 °C(lit.)
alpha 
165 º (c=1, CHCl3,on dry ba)
Boiling point:
492.11°C (rough estimate)
Density 
0.9967 (rough estimate)
refractive index 
162 ° (C=1, MeOH)
solubility 
Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride.
pka
pKa 5.56±0.1 (Uncertain)
form 
Crystalline Powder
color 
White to off-white
optical activity
[α]22/D +170.0°, c = 1 in chloroform
Water Solubility 
SOLUBLE IN ACETIC ACID
Merck 
14,3590
BRN 
2229654
CAS DataBase Reference
471-53-4(CAS DataBase Reference)
EPA Substance Registry System
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3.beta.,20.beta.)-(471-53-4)

SAFETY

Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  22-24/25
WGK Germany  3
RTECS  RK0180000
HS Code  29189900

Enoxolone price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich G10105 18β-Glycyrrhetinic acid 97% 471-53-4 10g $105 2018-11-20 Buy
Sigma-Aldrich G10105 18β-Glycyrrhetinic acid 97% 471-53-4 25g $196 2018-11-20 Buy
TCI Chemical G0149 Glycyrrhetic Acid >97.0%(T) 471-53-4 1g $22 2018-11-22 Buy
TCI Chemical G0149 Glycyrrhetic Acid >97.0%(T) 471-53-4 25g $173 2018-11-22 Buy
Cayman Chemical 11845 β-Glycyrrhetinic Acid ≥98% 471-53-4 1g $25 2018-11-13 Buy

Enoxolone Chemical Properties,Uses,Production

Chemical Properties

white or greyish-white crystalline powder

Uses

An anti-inflammatory (topical).

Uses

antitussive, antiinflammatory, antibacterial

Uses

The aglycone of the triterpenoid Glyccyrrhizic acid.

Uses

glycyrrhetinic acid is anti-irritant, anti-allergenic, anti-inflammatory, skin-lightening, and smoothing properties are attributed to this ingredient, which is also a carrier. It is the organic compound derived from glycyrrhizic acid or shredded licorice roots.

Definition

ChEBI: A pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30.

Anticancer Research

Glycyrrhetinic acid in combinationwith etoposide inhibits thetopoisomerase 2α and inducesapoptosis
Cai et al.(2017)

Anticancer Research

It was reported that GA at noncytotoxic concentrationshowed synergistic effect in combination with anticancer drug, etoposide (VP-16).Specifically, GA enhanced cytotoxicity through regulating topoisomerase II-αtargeted by etoposide. Also, GA sensitized the cells to etoposide through elevatingtopoisomerase II-α with a 2.4-fold rate at 12 h time point. From 12 to 48 h, GAhalved the expression of topoisomerase II-α and stimulated apoptosis, whichexhibited its antineoplastic effect. They reported that GA was more potentiallyeliminating the TNBC cells when compared with Glycyrrhizin Acid (Cai et al. 2017).

Enoxolone Preparation Products And Raw materials

Raw materials

Preparation Products


Enoxolone Suppliers

Global( 288)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hebei Guanlang Biotechnology Co., Ltd.
+86-0311-66562153 whatsapp +8615203118427
+86-0311-66562153 sales@crovellbio.com CHINA 406 50
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3202 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21909 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20675 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1367 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32451 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6373 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 25795 58
Kono Chem Co., Ltd
+86-132 8924 6953(Whatsapp/Wechat)
+86-29-86107037 info@konochemical.com CHINA 2540 58

View Lastest Price from Enoxolone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-16 Enoxolone
471-53-4
US $1.00 / KG 1G 98% 100KG career henan chemical co
2018-08-07 Enoxolone
471-53-4
US $10.00 / KG 1KG 65%,70%,99.99% 100 MT per month Hebei Guanlang Biotechnology Co., Ltd.

Enoxolone Spectrum


471-53-4(Enoxolone)Related Search:


  • 3.beta.-Hydroxy-11-oxo-12-oleanen-30-oicacid
  • 3-beta-hydroxy-11-oxo-olean-12-en-30-oicaci
  • 3-beta-hydroxy-11-oxoolean-12-en-30-oicacid
  • 3-hydroxy-11-oxo-,(3.beta.,20.beta.)-Olean-12-en-29-oicacid
  • 3-hydroxy-11-oxo-,(3beta,20beta)-olean-12-en-29-oicaci
  • 3-Hydroxy-11-oxo-12-oleanen-30-oicacid
  • 3BETA-HYDROXY-11-OXO-18BETA, 20BETA-OLEAN-12-EN-29-OIC ACID
  • 3BETA-HYDROXY-11-OXO-18BETA-OLEAN-12-EN-30-OIC ACID
  • 3b-hydroxy-11-oxo-18b,20b-olean-12-en-29-oic acid
  • 3B-HYDROXY-11-OXO-18B-OLEAN-12-EN-30-OIC ACID
  • GLYCYRRHETINIC ACID
  • GLYCYRRHETIC ACID
  • GLYCYRRHETINIC ACID, 18B-
  • ENOXOLONE
  • ENOLOXONE
  • B-GLYCYRRHETINIC ACID
  • B-GLYCYRRNETINIC ACID
  • URALENIC ACID
  • 3β-Hydroxy-11-oxoolean-12-en-30-oic acid
  • 18-beta-Glycyrrhetinic acid, 98+%
  • Glycyrrhetinic
  • ENOXACIN GLUCONATE/18BETA-GLYCYRRHETINIC ACID
  • GLCYRRHETINIC ACID
  • CARBENOXOLONE(P)
  • Clycyrrhetinic Acid
  • 18-Beta-Glycyrrheticacid,Uralenicacid
  • 18β-Glycyrrhetic acid
  • Arthrodont
  • GM 1658
  • NSC 35347
  • Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)-
  • Olean-12-en-30-oic acid, 3β-hydroxy-11-oxo- (8CI)
  • PO 12
  • STX 352
  • Subglycyrrhelinic acid
  • Uralenic acid (7CI)
  • GLYCERRHETINICACID
  • (3β,20b)-3-Hydroxy-11-oxo-olean-12-en-29-oic acid
  • 18-beta-GLYCYRRHETINIC ACID hplc
  • 18 BETA
  • 18b-Glycyrrhetic acid
  • 18beta-Glycyrrhetinic acid 97%
  • Enoxolone (18-β-glycyrrhetinic acid)
  • 3β-Hydroxy-11-oxoolean-12-en-30-olic acid
  • Glycyrrhetinate
  • 19β-Glycyrrhetinic acid
  • 20β-Glycyrrhetinic acid
  • 18-β-Glycyrrhetinic acid, 98+%
  • 18-beta-glycyrrheticacid
  • Enoxolone, 3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid
  • Aloe Vera, Freeze Dried Powder
  • Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3b,20b)-
  • (20S)-3β-Hydroxy-11-oxo-5α-olean-12-en-29-oic acid
  • GLYCYRRHETINIC ACID, 18B-(P)
  • Glycyrrhetinic acid ,98%
  • 18β-Glycyrrhetinic acid,3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid, Enoxolone
  • GLYCYRRHETINIC ACID, 18B-(SH)
  • 18 β-Glycyrrhetinic Acid / Enoxolone
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