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Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

ENDOTHAL Properties

Melting point:
1.431 g/cm3
storage temp. 
+2C to +8C
White solid
Water Solubility 
Soluble in water (>25 mg/ml), methanol, acetone, and DMSO. Insoluble in benzene.
CAS DataBase Reference
145-73-3(CAS DataBase Reference)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T
Risk Statements  21-25-36/37/38
Safety Statements  36/37/39-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  1
RTECS  RN7875000
HazardClass  6.1(a)
PackingGroup  II
Toxicity LD50 in adult male, female rats (mg/kg): 57, 46 orally (Gaines, Linder)
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

ENDOTHAL price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 324760-M Endothall 145-73-3 20mg-m $75.2 2018-11-20 Buy
Alfa Aesar J60948 Endothall 145-73-3 100mg $325 2018-11-13 Buy
Cayman Chemical 17404 Endothall ≥95% 145-73-3 50mg $113 2018-11-13 Buy
Cayman Chemical 17404 Endothall ≥95% 145-73-3 10mg $25 2018-11-13 Buy
Cayman Chemical 17404 Endothall ≥95% 145-73-3 100mg $148 2018-11-13 Buy

ENDOTHAL Chemical Properties,Uses,Production

Chemical Properties

Endothall, when pure, is a white crystalline solid. The technical grade is a light brown liquid


Defoliant, herbicide.


Preemergence and postemergence herbicide for control of broad-leaved weeds and annual grass in vegetable crops. The disodium and dipotassium salts are used as defoliants and herbicides.

General Description

The monohydrate is in the form of colorless crystals. Non corrosive. Used as a selective herbicide.

Air & Water Reactions

Stable up to 90°C, above which ENDOTHAL undergoes slow hydrolysis.

Reactivity Profile

A phthalic acid derivative.


Strong irritant to eyes and skin.

Agricultural Uses

Herbicide, Algaecide: Endothall is used as a cotton defoliant and as a selective contact herbicide on both terrestrial and aquatic weeds. The potassium and amine salts of endothall are used as aquatic herbicides to control a variety of plants including plankton, pondweed, niad, coontail, milfoil, elodea, and algaes in water bodies and rice fields. Endothall is also used to control annual grass and broadleaf weeds in sugar beets, spinach and turf. It reduces sucker branch growth in hops. Endothall is a desiccant to aid the harvest of alfalfa, potatoes, clover, and cotton. Not approved for use in EU countries. Approved for use in the U.S. and other countries. There are 24 global suppliers.

Trade name


Safety Profile

Poison by ingestion. Very irritating to skin, eyes, and mucous membranes. Causes dlarrhea. When heatedto decomposition it emits acrid smoke and fumes

Potential Exposure

Endothall is dicarboxylic acid defoliant and herbicide used on both terrestrial and aquatic weeds.

First aid

Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim warm and quiet. Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed. Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.

Environmental Fate

Biological. Incubation of 14C-ring labeled endothall (10 mg/mL) by Arthrobacter sp., which was isolated from pond water and a hydrosol, in aerobic sediment-water suspensions revealed that after 30 days, 40% evolved as 14CO2. Glutamic acid was the major transformation product. Minor products were alanine, citric and aspartic acids and unidentified products, some of which were tentatively identified as phosphate esters (Sikka and Saxena, 1973). In pond water treated with endothall (2 and 4 ppm), detectable levels were found after 7 days (Sikka and Rice, 1973). Biodegradation was rapid in an Ontario soil sample. After 1 week, 70% of endothall added was converted to carbon dioxide (Simsiman et al., 1976).
Chemical/Physical. Reacts with bases forming water-soluble salts. Above 90°C, endothall is slowly converted to the anhydride (Windholz et al., 1983; Hartley and Kidd, 1987) and water (Humburg et al., 1989). Endothall is stable to light (Hartley and Kidd, 1987).


UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2588 Pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.


Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic, and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur)

Waste Disposal

Small quantities may be disposed of by burial in soil which is rich in organic matter. Large quantities are best disposed of by incineration. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (5100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office

ENDOTHAL Preparation Products And Raw materials

Raw materials

Preparation Products

ENDOTHAL Suppliers

Global( 53)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19958 60
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32764 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76
BEST-REAGENT 028-85973071 028-85973075
028-85973075 China 9968 57
Chengdu Ai Keda Chemical Technology Co., Ltd. 4008-755-333 ; 028-86676798 ; 028-86757656
028-86757656 China 9884 55
Shanghai Tauto Biotech Co., Ltd 0086-21-51320588
0086-21-51320502 China 3582 66
Clearsynth Labs Limited +91-22-26355700
+91-22-26355701 India 9774 58
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
021-33632979 China 3740 58
Tianjin Anhao Biological Technology Co., Ltd. China 5751 55
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794
021-61478794 China 9816 50


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