InSolution Rapamycin - Calbiochem
- CAS No.
- Chemical Name:
- InSolution Rapamycin - Calbiochem
- Synonyms
- InSolution Rapamycin - Calbiochem
- CBNumber:
- CB84817378
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
InSolution Rapamycin - Calbiochem price More Price(2)
InSolution Rapamycin - Calbiochem Chemical Properties,Uses,Production
General Description
Selectively inhibits the phosphorylation and activation of p70 S6 kinase (IC50 = 50 pM). Prevents the translational activation of IGF-II. Also prevents resting T-cells from entering the cell cycle, but does not directly arrest cell cycle progression. Shown to inhibit later signaling events, such as p110Rb phosphorylation, p34cdc2 kinase activation, and cyclin A synthesis. Exhibits strong binding to FK-506 binding proteins. Also reported to induce apoptosis in a murine B-cell line, to inhibit lymphokine-induced cell proliferation at the G1 phase, and to irreversibly arrest Saccharomyces cerevisiae cells in the G1 phase.
Biochem/physiol Actions
Primary TargetMammalian target of rapamycin (mTOR)
InSolution Rapamycin - Calbiochem Preparation Products And Raw materials
Raw materials
Preparation Products
InSolution Rapamycin - Calbiochem Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
InSolution Rapamycin - Calbiochem