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Pomalidomide-PEG3-CO2H

Pomalidomide-PEG3-CO2H Structure
Pomalidomide-PEG3-CO2H structure
CAS No.
2138440-82-9
Chemical Name:
Pomalidomide-PEG3-CO2H
Synonyms
Pomalidomide-PEG3-COOH;3-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)propanoic acid;Poma-PEG3-COOH;Pomalidomide-PEG3-CO2H;POMALIDOMIDE-PEG 3-CO 2 H;Pomalidomide 4'-PEG3-acid;Thalidomide-NH-PEG3-C2-COOH;Pomalidomide-PEG3-CO2H >=95%;Thalidomide-4-NH-PEG3-C2-COOH;Thalidomide-NH-PEG3-propionic acid
CBNumber:
CB84846411
Molecular Formula:
C22H27N3O9
Molecular Weight:
477.46
MDL Number:
MFCD32173779
MOL File:
2138440-82-9.mol
MSDS File:
SDS
Last updated:2024-07-02 08:55:37
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Pomalidomide-PEG3-CO2H Properties

Boiling point 757.8±60.0 °C(Predicted)
Density 1.417±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in DMSO
pka 4.28±0.10(Predicted)
form Solid
color Light yellow to green yellow

Pomalidomide-PEG3-CO2H price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 901504 Pomalidomide-PEG3-CO2H ≥95% 2138440-82-9 50MG $1240 2023-06-20 Buy
Iris Biotech GmbH PTC1170 Pomalidomide-PEG3-COOH 2138440-82-9 50mg $702 2021-12-16 Buy
Product number Packaging Price Buy
901504 50MG $1240 Buy
PTC1170 50mg $702 Buy

Pomalidomide-PEG3-CO2H Chemical Properties,Uses,Production

Uses

Protein degrader builiding block Pomalidomide-PEG3-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

storage

Store at -20°C

Pomalidomide-PEG3-CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide-PEG3-CO2H Suppliers

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040 sales@myuchem.com China 7193 58
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
Nanjing Bicbiotechnology Co., Ltd 		+86-2552131256 +86-18251840740 sales@bicbiotech.com China 6000 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Suzhou ARTK Medchem Co., Ltd. 		+8618168183658 sales1@artkmedchem.com China 39010 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7182 65
ChemShuttle, Inc. 0510-83588313-802 18800520310; sales@chemshuttle.com China 2996 62
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Shanghai UCHEM Inc. 		58
Alfa Chemistry 		58
Nanjing Bicbiotechnology Co., Ltd 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Xian confluore Biological Technology Co., Ltd. 		58
Aladdin Scientific 		58
Suzhou ARTK Medchem Co., Ltd. 		58
Daicel Chiral Technologies (China)CO.,LTD 65
ChemShuttle, Inc. 62
Sigma-Aldrich 80

View Lastest Price from Pomalidomide-PEG3-CO2H manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-PEG3-COOH pictures 2024-04-02 Pomalidomide-PEG3-COOH
2138440-82-9
 US $0.00 / mg 250mg >99.00% 250mg Xian confluore Biological Technology Co., Ltd.

2138440-82-9(Pomalidomide-PEG3-CO2H)Related Search:

Pomalidomide-PEG5-CO2H POMALIDOMIDE-PEG1-CO2H Pomalidomide-PEG3-Amine HCl salt Pomalidomide-PEG4-CO2H E3 Ligase Ligand-Linker Conjugates 1
POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG1-azide Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG3-N3
Pomalidomide-PEG6-butyl iodide 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione E3 Ligase Ligand-Linker Conjugates 22 Pomalidomide-PEG2-butyl iodide Pomalidomide-PEG4-azide
Pomalidomide-PEG2-N3 E3 ligase Ligand-Linker Conjugates 50 Pomalidomide-PEG5-Alkyne

1of4

POMALIDOMIDE-PEG 3-CO 2 H Pomalidomide-PEG3-CO2H 3-[2-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoic acid Propanoic acid, 3-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]- Pomalidomide-PEG3-CO2H >=95% Pomalidomide-PEG3-COOH 3-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)propanoic acid Thalidomide-NH-PEG3-propionic acid Thalidomide-NH-PEG3-C2-COOH 3-[2-[2-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]ethoxy]ethoxy]propanoic Acid Thalidomide-4-NH-PEG3-C2-COOH Poma-PEG3-COOH Pomalidomide 4'-PEG3-acid 3-{2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)ethoxy]ethoxy}propanoic acid 2138440-82-9 C22H27N3O9 peg