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SCH 58261

CAS No.
160098-96-4
Chemical Name:
SCH 58261
Synonyms
CS-2187;SCH-58261;SCH 58261;Butanoicacid,4-bromo-5-oxo-,ethylester;Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor;2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine
CBNumber:
CB8497477
Molecular Formula:
C18H15N7O
Molecular Weight:
345.36
MDL Number:
MFCD00933778
MOL File:
160098-96-4.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

SCH 58261 Properties

Melting point 223 °C
Density 1.54±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMSO: >10 mg/mL, soluble
pka 2.78±0.30(Predicted)
form solid
color off-white
FDA UNII 4309023MAH

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
HS Code  2934.99.3000
NFPA 704
0
2 0

SCH 58261 price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S4568 SCH 58261 ≥98% (HPLC), solid 160098-96-4 5mg $200 2024-03-01 Buy
Sigma-Aldrich S4568 SCH 58261 ≥98% (HPLC), solid 160098-96-4 25mg $304.8 2024-03-01 Buy
TCI Chemical C3599 SCH 58261 160098-96-4 5MG $145 2024-03-01 Buy
TCI Chemical C3599 SCH 58261 160098-96-4 25MG $532 2024-03-01 Buy
Cayman Chemical 19676 SCH 58261 ≥98% 160098-96-4 1mg $32 2024-03-01 Buy
Product number Packaging Price Buy
S4568 5mg $200 Buy
S4568 25mg $304.8 Buy
C3599 5MG $145 Buy
C3599 25MG $532 Buy
19676 1mg $32 Buy

SCH 58261 Chemical Properties,Uses,Production

Uses

SCH 58261 is a potent and selective A2A adenosine receptor antagonist.

Definition

ChEBI: LSM-3822 is a member of triazolopyrimidines.

Biological Activity

Potent and selective A 2A adenosine receptor competitive antagonist (K i = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A 1 , A 2B and A 3 receptors, respectively.

Biochem/physiol Actions

SCH 58261 reduces the levels of TNF-α, Fas-L, Bax expression and activation of JNK-MAPK pathway. It has neuroprotective effects as it reduces demyelination of the neurons. SCH 58261 increases the concentration of secretion of dopamine and elicits locomotor sensitization, an attractive option in the possible treatment of Parkinson′s disease.

storage

Store at RT

3326-71-4
160098-96-4
Synthesis of SCH 58261 from Furan-2-carbohydrazide

SCH 58261 Preparation Products And Raw materials

Global( 105)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58

View Lastest Price from SCH 58261 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- pictures 2020-03-06 7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-
160098-96-4
US $2.00 / g 1g 95~99.9% 5KG Career Henan Chemical Co

SCH 58261 Spectrum

7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine CS-2187 SCH-58261;SCH 58261 4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine 4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine Butanoicacid,4-bromo-5-oxo-,ethylester Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor 160098-96-4 C18H15N7O Adenosine receptor