Nerolidol
- CAS No.
- 40716-66-3
- Chemical Name:
- Nerolidol
- Synonyms
- 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (E)-;E-Nerolidol;(E)-Nerolidol;(6E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol;trans-Nerolidal solution;Nerolidol;trans-Form;Nerolidol (E);Einecs 255-053-4;Trans-(E)-Nerolidol
- CBNumber:
- CB8497598
- Molecular Formula:
- C15H26O
- Molecular Weight:
- 222.37
- MDL Number:
- MFCD00008911
- MOL File:
- 40716-66-3.mol
| Boiling point | 145-146 °C12 mm Hg(lit.) |
|---|---|
| Density | 0.876 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 230 °F |
| storage temp. | -20°C |
| solubility | DMF: miscible,DMSO: miscible,Ethanol: miscible,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
| pka | 14.40±0.29(Predicted) |
| Odor | at 100.00 %. floral green citrus woody waxy |
| Odor Type | floral |
| JECFA Number | 1646 |
| Merck | 13,6501 |
| BRN | 5731231 |
| Stability | Light Sensitive |
| LogP | 5.316 (est) |
| EWG's Food Scores | 1 |
| FDA UNII | FG5V0N8P2H |
| NIST Chemistry Reference | 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (e)-(40716-66-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H319-H410 | |||||||||
| Precautionary statements | P261-P264-P273-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 1 | |||||||||
| F | 10-23 | |||||||||
| Toxicity | Both the acute oral LD50 in rats and the acute dermal LD50 in rabbits exceeded 5 g/kg (Russell. 1973). | |||||||||
| NFPA 704 |
|
Nerolidol price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 18143 | trans-Nerolidol analyticalstandard | 40716-66-3 | 100mg | $81.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 04610590 | trans-Nerolidol primary pharmaceutical reference standard | 40716-66-3 | 50mg | $158.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | CRM40742 | trans-Nerolidal solution certified reference material, 2000?μg/mL in methanol, ampule of 1?mL | 40716-66-3 | 1mL | $95.2 | 2022-05-15 | Buy |
| Cayman Chemical | 25778 | trans-Nerolidol | 40716-66-3 | 50mg | $27 | 2024-03-01 | Buy |
| Cayman Chemical | 25778 | trans-Nerolidol | 40716-66-3 | 100mg | $48 | 2024-03-01 | Buy |
Nerolidol Chemical Properties,Uses,Production
Description
trans-Nerolidol is a sesquiterpene that has been found in various plants, including C. sativa, and has diverse biological activities, including antimicrobial, antioxidant, anticancer, and insecticidal properties. In a disc assay, trans-nerolidol inhibits the growth of S. aureus, B. subtilis, E. coli, and S. cerevisiae with zones of inhibition measuring 10, 9, 10, and 4 mm, respectively. It reduces viability of CaCo-2 adenocarcinoma cells with an IC50 value of 28.7 mg/L and reduces production of reactive oxygen species (ROS). trans-Nerolidol is insecticidal against A. aegypti larvae with a 24-hour LC50 value of 9 mg/L.
Occurrence
Reported to be found in cabreuva oil, oil of neroli, balsam Peru, ylang ylang and many others (Gildemeister & Hoffman, 1959).
Uses
Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.
Preparation
By isolation from a suitable essential oil or by chemical synthesis.
Definition
ChEBI: Nerolidol is a farnesane sesquiterpenoid that is dodeca-1,6,10-triene which carries methyl groups at positions 3, 7 and 11 and a hydroxy group at position 3. It is a natural product that is present in various flowers and plants with a floral odor. Chemically, it exists in two geometric isomers, trans and cis forms. It is widely used in cosmetics (e.g. shampoos and perfumes), in non-cosmetic products (e.g. detergents and cleansers) and also as a food flavoring agent. It has a role as a flavouring agent, a cosmetic, a pheromone, a neuroprotective agent, an antifungal agent, an anti-inflammatory agent, an antihypertensive agent, an antioxidant, a volatile oil component, an insect attractant and a herbicide. It is a farnesane sesquiterpenoid, a tertiary allylic alcohol and a volatile organic compound.
Nerolidol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
| Kindchem(Nanjing)Co.,Ltd | +86-025-025-85281586 +8618651653755 | sales@kindchem.cn | China | 1227 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
40716-66-3(Nerolidol)Related Search:
1of4