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N,N-Dimethyltryptamine

N,N-Dimethyltryptamine structure

CAS No.: 61-50-7

Chemical Name:: N,N-Dimethyltryptamine

Synonyms: Dimethyltryptamine;N,N-DMT;Dimethyltryptamine (dmt);dmt(psychogenic);Dimetiltriptamin;N,N-Dimethyltryptamine;NOMEGA,NOMEGA-Dimethyltry;N,N-DMT (exempt preparation);3-(2-Dimethylaminoethyl)indole;2-(3-Indolyl)ethyldimethylamine

CBNumber:: CB8498045

Molecular Formula:: C12H16N2

Molecular Weight:: 188.27

MDL Number:: MFCD00055989

MOL File:: 61-50-7.mol

Last updated:2023-05-29 13:57:48

N,N-Dimethyltryptamine Properties

Melting point	42-44°C
Boiling point	bp 60-80°
Density	1.0580 (rough estimate)
refractive index	1.5430 (estimate)
Flash point	9℃
storage temp.	Store at -20°C
solubility	DMSO: soluble15mg/mL, clear
form	powder
pka	8.68 (ethanol-water)
color	white to beige
FDA UNII	WUB601BHAA
NIST Chemistry Reference	N,N-Dimethyltryptamine(61-50-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H336
Precautionary statements	P261-P271-P304+P340+P312-P403+P233-P405-P501
RIDADR	1544
WGK Germany	3
HazardClass	6.1(b)
PackingGroup	III
DEA Controlled Substances	CSCN: 7435 CAS SCH: I NARC: N

N,N-Dimethyltryptamine Chemical Properties,Uses,Production

Chemical Properties

Tan Solid

Uses

A labelled endogenous Sigma-1 receptor regulator.

Uses

It is an endogenous Sigma-1 receptor regulator.

Definition

ChEBI: A tryptamine derivative having two N-methyl substituents on the side-chain.

Synthesis Reference(s)

The Journal of Organic Chemistry, 59, p. 3738, 1994 DOI: 10.1021/jo00092a046

General Description

Dimethyltryptamine is a very weak hallucinogen, activeonly by inhalation or injection, with a short duration of action.It possesses pronounced sympathomimetic (NE) sideeffects.

Biological Activity

Endogenous σ 1 receptor ligand and psychoactive plant compound (K i = 14.8 μ M). Binding to σ 1 inhibits voltage-gated Na + channels and is responsible for the behavioral effects of DMT. Also a 5-HT 2A receptor agonist and inhibitor of 5-HT uptake at plasma membrane serotonin transporters (SERT) (K i = 4.0 μ M).

N,N-Dimethyltryptamine synthesis

Synthesis of N,N-Dimethyltryptamine from 3-(2-BROMOETHYL)INDOLE and Dimethylamine

N,N-Dimethyltryptamine Preparation Products And Raw materials

Raw materials

N-Allyl-N-(2-fluorophenyl)amine 1H-Indole-3-ethanamine, 5,6-dibromo-N,N-dimethyl- 1H-Indole-3-ethanamine, 5-[(2-methyl-2H-tetrazol-5-yl)methyl]- 5-BROMO-N,N-DIMETHYLTRYPTAMINE INDOLE-3-(N,N-DIMETHYL)GLYOXYLAMIDE

TRYPTAMINE HYDROCHLORIDE 2-Aminophenethanol INDOLE-3-(N,N-DIMETHYL)ACETAMIDE 3-(2-BROMOETHYL)INDOLE Dimethylamine

Methanol carbon monoxide Tryptamine N,N-Dimethylallylamine 2-Dimethylaminoethanol

Formaldehyde

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Preparation Products

61-50-7(N,N-Dimethyltryptamine)Related Search:

Indometacin 1-METHYL-DL-TRYPTOPHAN 5-Methoxytryptamine 3-(2-Aminoethyl)-6-methoxyindole Dimethyl sulfate

Dimethyl ether Dimethyl carbonate Dimethyl sulfoxide ETHANE Indole

Indole-3-acetic acid Dimethyl sulfide Dimethyl fumarate N,N-Dimethylcyclohexylamine N,N-Dimethylformamide

N,N-Dimethyldodecylamine N,N-Dimethylallylamine Tryptamine Dimethyltryptamine

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N,N-DIMETHYLTRYPTAMINE METHANOL*SOLUTION 1H-Indole-3-ethanamine, N,N-dimethyl- 2-(1H-Indol-3-yl)-N,N-dimethylethanamine 2-(3-Indolyl)ethyldimethylamine 2-(indol-3-yl)ethyldimethylamine 3-(2-(dimethylamino)ethyl)-indol 3-(2-Dimethylaminoethyl)indole dmt(psychogenic) Indole, 3-[2-(dimethylamino)ethyl]- n,n-dimethyl-1h-indole-3-ethanamin N,N-dimethyl-1H-indole-3-ethylamine NOMEGA,NOMEGA-Dimethyltry N,N-Dimethyl-1H-indole-3-ethanamine 3-[2-(Dimethylamino)ethyl]-1H-indole N,N-Dimethyl-2-(1H-indol-3-yl)ethanamine N,N-Dimethyl-2-(1H-indol-3-yl)ethylamine N,N-Dimethyltryptamine N,N-DMT (exempt preparation) N,N-Dimethyltryptamine (DMT) solution Dimetiltriptamin Dimethyltryptamine Dimethyltryptamine (dmt) N,N-DMT 61-50-7 C12H10D6N2 Amines Heterocycles Intermediates & Fine Chemicals Neurochemicals Pharmaceuticals Isotope Labelled Compounds Pharmaceutical Intermediates