Tocainide hydrochloride
- CAS No.
- 35891-93-1
- Chemical Name:
- Tocainide hydrochloride
- Synonyms
- Xylotocan;TOCAINIDE HCL;Unii-2K7I38ckn5;tonocardhydrochloride;tocainide hydrochloride;TOCAINIDE HYDROCHLORIDE (125 MG);Tocainide hydrochloride USP/EP/BP;Tocainide Hydrochloride (1667552);2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride;2-amino-n-(2,6-dimethylphenyl)-propanamidmonohydrochloride
- CBNumber:
- CB8500546
- Molecular Formula:
- C11H17ClN2O
- Molecular Weight:
- 228.71848
- MDL Number:
- MFCD00941502
- MOL File:
- 35891-93-1.mol
- MSDS File:
- SDS
| Melting point | 244-245°C |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Off-White |
| EWG's Food Scores | 1 |
| FDA UNII | 2K7I38CKN5 |
Tocainide hydrochloride price More Price(1)
Tocainide hydrochloride Chemical Properties,Uses,Production
Uses
Tonocard(AstraZeneca).
Uses
Tocainide Hydrochloride is used as an anti-arrythmic drug as myocardial depressants.
General Description
Tocainide hydrochloride,2-amino-2＇ ,6 ＇-propionoxyxylidide hydrochloride (Tonocard)(pKa 7.7), is an analog of lidocaine. It is orally active and haselectrophysiological properties like those of lidocaine. Totalbody clearance of tocainide hydrochloride is only166 mL/min, suggesting that hepatic clearance is not large.Because of low hepatic clearance, the hepatic extraction ratiomust be small; therefore, tocainide hydrochloride is unlikelyto be subject to a substantial first-pass effect. The drug differsfrom lidocaine, in that it lacks two ethyl groups, which providestocainide hydrochloride some protection from first-passhepatic elimination after oral ingestion. Tocainide hydrochlorideis hydrolyzed in a manner similar to that of lidocaine.None of its metabolites is active.
Clinical Use
Tocainide hydrochloride is classed as a IB antiarrhythmicagent and used orally to prevent or treat ventricular ectopyand tachycardia. The drug is given in 400- to 600-mgdoses every 8 hours.
Veterinary Drugs and Treatments
Veterinary experience with tocainide is limited. At this time, dogs are the only veterinary species where enough clinical experience has been garnered to recommend its use. It is indicated for the oral therapy of ventricular arrhythmias, principally ventricular tachycardia and ventricular premature complexes. In humans, response to lidocaine can usually predict whether tocainide might be effective.
Tocainide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3791 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9553 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29474 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Shanxi New Baoyuan Pharmaceutical Co., Ltd. | 0352-7606558 | zhaoshujun@xinbaoyuanpharm.com | China | 10 | 58 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9823 | 79 |
View Lastest Price from Tocainide hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | Tocainide hydrochloride USP/EP/BP
35891-93-1
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2021-07-20 | Tocainide hydrochloride
35891-93-1
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Tocainide hydrochloride USP/EP/BP
35891-93-1
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Tocainide hydrochloride
35891-93-1
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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