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Tocainide hydrochloride

Tocainide hydrochloride
Tocainide hydrochloride structure
CAS No.
35891-93-1
Chemical Name:
Tocainide hydrochloride
Synonyms
Xylotocan;TOCAINIDE HCL;Unii-2K7I38ckn5;tonocardhydrochloride;tocainide hydrochloride;TOCAINIDE HYDROCHLORIDE (125 MG);Tocainide hydrochloride USP/EP/BP;2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride;2-amino-n-(2,6-dimethylphenyl)-propanamidmonohydrochloride;2-amino-n-(2,6-dimethylphenyl)propanamidemonohydrochloride
CBNumber:
CB8500546
Molecular Formula:
C11H17ClN2O
Formula Weight:
228.71848
MOL File:
35891-93-1.mol

Tocainide hydrochloride Properties

EWG's Food Scores
1
FDA UNII
2K7I38CKN5
SAFETY
  • Risk and Safety Statements
HS Code  2924296000

Tocainide hydrochloride price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T0202 Tocainide hydrochloride ≥98% (HPLC), solid 35891-93-1 10 mg $164 2021-12-16 Buy
Sigma-Aldrich T0202 Tocainide hydrochloride ≥98% (HPLC), solid 35891-93-1 50 mg $652 2021-12-16 Buy
TRC T525453 Tocainide hydrochloride 35891-93-1 1.25mg $45 2021-12-16 Buy

Tocainide hydrochloride Chemical Properties,Uses,Production

Uses

Tonocard(AstraZeneca).

General Description

Tocainide hydrochloride,2-amino-2' ,6 '-propionoxyxylidide hydrochloride (Tonocard)(pKa 7.7), is an analog of lidocaine. It is orally active and haselectrophysiological properties like those of lidocaine. Totalbody clearance of tocainide hydrochloride is only166 mL/min, suggesting that hepatic clearance is not large.Because of low hepatic clearance, the hepatic extraction ratiomust be small; therefore, tocainide hydrochloride is unlikelyto be subject to a substantial first-pass effect. The drug differsfrom lidocaine, in that it lacks two ethyl groups, which providestocainide hydrochloride some protection from first-passhepatic elimination after oral ingestion. Tocainide hydrochlorideis hydrolyzed in a manner similar to that of lidocaine.None of its metabolites is active.

Clinical Use

Tocainide hydrochloride is classed as a IB antiarrhythmicagent and used orally to prevent or treat ventricular ectopyand tachycardia. The drug is given in 400- to 600-mgdoses every 8 hours.

Veterinary Drugs and Treatments

Veterinary experience with tocainide is limited. At this time, dogs are the only veterinary species where enough clinical experience has been garnered to recommend its use. It is indicated for the oral therapy of ventricular arrhythmias, principally ventricular tachycardia and ventricular premature complexes. In humans, response to lidocaine can usually predict whether tocainide might be effective.

Tocainide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Tocainide hydrochloride Suppliers

Global( 33)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26782 60
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
Shaanxi Dideu Medichem Co. Ltd
13772537765
029-88380327 1010@dideu.com CHINA 3993 58
Career Henan Chemica Co
15093356674 0371-55982848
0371-86658258 laboratory@coreychem.com CHINA 30290 58
Shaanxi Dideu Medichem Co. Ltd
18192503167 +86-29-89586680
+86-29-88380327 1005@dideu.com CHINA 9938 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 30014 58
InvivoChem
+1-708-310-1919
708-557-7486 sales@invivochem.com United States 6398 58
Shanxi New Baoyuan Pharmaceutical Co., Ltd. --
-- zhaoshujun@xinbaoyuanpharm.com China 10 58
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
86-21-63290778 86-21-63218885 sj_scrc@sinopharm.com China 9844 79
Boen pharm 86 512-62572107 62962707
86 512-62922078 sales@boenpharm.com China 800 58

View Lastest Price from Tocainide hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-08-12 Tocainide hydrochloride USP/EP/BP
35891-93-1
US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
2021-07-20 Tocainide hydrochloride
35891-93-1
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd

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