ChemicalBook >> CAS DataBase List >>SRI-29329

SRI-29329

CAS No.
2086809-58-5
Chemical Name:
SRI-29329
Synonyms
SRI-29329;Cyclin dependent kinase,inhibit,SRI29329,SRI-29329,Inhibitor,SRI 29329,CDK;9H-Purine-2,6-diamine, N2-[(1S,2S)-2-aminocyclohexyl]-N6-(3-chlorophenyl)-9-(1-methylethyl)-
CBNumber:
CB85867459
Molecular Formula:
C20H26ClN7
Molecular Weight:
399.92
MDL Number:
MFCD32899878
MOL File:
2086809-58-5.mol
Last updated:2023-05-21 10:59:17

SRI-29329 Properties

storage temp. Store at -20°C
solubility DMSO : 50 mg/mL (125.03 mM; Need ultrasonic)

SRI-29329 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0083792 SRI-29329 99.52% 2086809-58-5 5mg $250 2021-12-16 Buy
ChemScene CS-0083792 SRI-29329 99.52% 2086809-58-5 10mg $400 2021-12-16 Buy
ChemScene CS-0083792 SRI-29329 99.52% 2086809-58-5 25mg $750 2021-12-16 Buy
ChemScene CS-0083792 SRI-29329 99.52% 2086809-58-5 50mg $1150 2021-12-16 Buy
Product number Packaging Price Buy
CS-0083792 5mg $250 Buy
CS-0083792 10mg $400 Buy
CS-0083792 25mg $750 Buy
CS-0083792 50mg $1150 Buy

SRI-29329 Chemical Properties,Uses,Production

Biological Activity

SRI-29329 is a specific CLK inhibitor, with IC50 values of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively[1]. SRI-29329 (compound 8) shows some modest (~5 fold) selectivity for CLK2 over CLK1 and CLK4 without significant CDK1,4,6 activity[1].

References

[1]. Yihui Shi, et al. A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore. Bioorg Med Chem Lett. 2017 Feb 1;27(3):406-412.

SRI-29329 Preparation Products And Raw materials

Raw materials

Preparation Products

SRI-29329 Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3500 55
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 5019 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9180 58
SRI-29329 9H-Purine-2,6-diamine, N2-[(1S,2S)-2-aminocyclohexyl]-N6-(3-chlorophenyl)-9-(1-methylethyl)- Cyclin dependent kinase,inhibit,SRI29329,SRI-29329,Inhibitor,SRI 29329,CDK 2086809-58-5