METFORMIN-D6, HYDROCHLORIDE
- CAS No.
- 1185166-01-1
- Chemical Name:
- METFORMIN-D6, HYDROCHLORIDE
- Synonyms
- metformin d6;Diabetosan-d6;Metiguanide-d6;Metformine-D6.HCl;Diabex-d6, Glucophage-d6;Metformin Impurity 9 HCl;METFORMIN-D6, HYDROCHLORIDE;Metformin hydrochloride salt;[2H6]-Metformin hydrochloride;1,1-Dimethyl-d6-biguanide HCl
- CBNumber:
- CB8649272
- Molecular Formula:
- C4H6ClD6N5
- Molecular Weight:
- 171.661550668
- MDL Number:
- MFCD06658649
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
METFORMIN-D6, HYDROCHLORIDE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 53183 | Metformin-(dimethyl-d6) hydrochloride analytical standard | 1185166-01-1 | 5mg | $648 | 2024-03-01 | Buy |
| Cayman Chemical | 16921 | Metformin-d6 (hydrochloride) ≥98% deuterated forms (d1-d6) | 1185166-01-1 | 500μg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 16921 | Metformin-d6 (hydrochloride) ≥98% deuterated forms (d1-d6) | 1185166-01-1 | 1mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 16921 | Metformin-d6 (hydrochloride) ≥98% deuterated forms (d1-d6) | 1185166-01-1 | 5mg | $469 | 2024-03-01 | Buy |
| Usbiological | M3009-75 | Metformin-d6, Hydrochloride | 1185166-01-1 | 1mg | $382 | 2021-12-16 | Buy |
METFORMIN-D6, HYDROCHLORIDE Chemical Properties,Uses,Production
Description
Metformin-d6 is intended for use as an internal standard for the quantification of metformin by GC- or LC-MS. Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day. It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD). Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53-\- human colon cancer mouse xenograft model, but has no effect on HCT116 p53-\- tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I. Formulations containing metformin have been used in the treatment of type 2 diabetes.
Chemical Properties
White Crystalline Solid
Uses
An oral hypoglycemic agent.
METFORMIN-D6, HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMSON PHARMA LIMITED | +91-8291074273 | k.das@simsonpharma.com | India | 228 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shandong Huijing bio-pharmaceutical Technology Co. , Ltd. | 15192151674 15192151674 | 1726957134@qq.com | China | 203 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 18521732826; | market@aladdin-e.com | China | 25015 | 65 |
View Lastest Price from METFORMIN-D6, HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-05-27 | Metformin D6 Hydrochloride
1185166-01-1
|
US $167.00-308.00 / mg | 10mg | 96% | 100 | Simson Pharma limited | |
 |
2023-05-27 | Metformin-D6 Hydrochloride
1185166-01-1
|
US $0.00-0.00 / mg | 1mg | 96% | 50 mg | Simson Pharma limited |
-
- Metformin D6 Hydrochloride
1185166-01-1
- US $167.00-308.00 / mg
- 96%
- Simson Pharma limited
-
- Metformin-D6 Hydrochloride
1185166-01-1
- US $0.00-0.00 / mg
- 96%
- Simson Pharma limited