ChemicalBook >> CAS DataBase List >>CGP 52432
CGP 52432
- CAS No.
- 139667-74-6
- Chemical Name:
- CGP 52432
- Synonyms
- P52432;CGP 52432;CGP52432 >=98% (HPLC);CGP 52432;CGP-52432;CGP 52432;(3-((3,4-dichlorobenzyl)amino)propyl)(diethoxymethyl)phosphinic acid;3-([[[(3,4-DICHLOROPHENYL)METHYL]AMINO]PROPYL] DIETHOXYMETHYL)PHOSPHINIC ACID;Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-;Inhibitor,CGP-52432,inhibit,Gamma-aminobutyric acid Receptor,CGP52432,GABA Receptor,γ-Aminobutyric acid Receptor
- CBNumber:
- CB8669551
- Molecular Formula:
- C15H24Cl2NO4P
- Molecular Weight:
- 384.24
- MDL Number:
- MFCD09878290
- MOL File:
- 139667-74-6.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Boiling point | 544.4±50.0 °C(Predicted) |
|---|---|
| Density | 1.258±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble1mg/mL, clear (warmed) |
| pka | 2.26±0.50(Predicted) |
| form | powder |
| color | white to beige |
| Water Solubility | Soluble in water (10mM, gentle warming) |
| FDA UNII | 4ZH667RFW5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
CGP 52432 price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0593 | CGP52432 ≥98% (HPLC) | 139667-74-6 | 5mg | $134 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0593 | CGP52432 ≥98% (HPLC) | 139667-74-6 | 25mg | $539 | 2024-03-01 | Buy |
| Cayman Chemical | 27212 | CGP 52432 | 139667-74-6 | 5mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 27212 | CGP 52432 | 139667-74-6 | 50mg | $841 | 2024-03-01 | Buy |
| Cayman Chemical | 27212 | CGP 52432 | 139667-74-6 | 10mg | $207 | 2024-03-01 | Buy |
CGP 52432 Chemical Properties,Uses,Production
Uses
CGP52432 has been used as a γ-aminobutyric acid B (GABAB) antagonist:
- to study its effects on the simulation of the onset of status epilepticus (SE) in mice
- for voltage-clamp recording in mice neurons
- to study its effects on the GABAB receptor-mediated neurotransmission in guinea pig hippocampus
Definition
ChEBI: 3-[(3,4-dichlorophenyl)methylamino]propyl-(diethoxymethyl)phosphinic acid is a dichlorobenzene.
Biological Activity
Potent, selective GABA B receptor antagonist (IC 50 = 85 nM).
Biochem/physiol Actions
CGP52432 participates in inhibiting the glycine overflow in the hippocampus.
storage
+4°C (desiccate)
CGP 52432 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 69)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
139667-74-6(CGP 52432)Related Search:
3-([[[(3,4-DICHLOROPHENYL)METHYL]AMINO]PROPYL] DIETHOXYMETHYL)PHOSPHINIC ACID
CGP 52432
CGP 52432;CGP-52432;CGP 52432
P52432
Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-
CGP52432 >=98% (HPLC)
(3-((3,4-dichlorobenzyl)amino)propyl)(diethoxymethyl)phosphinic acid
Inhibitor,CGP-52432,inhibit,Gamma-aminobutyric acid Receptor,CGP52432,GABA Receptor,γ-Aminobutyric acid Receptor
139667-74-6
C15H24Cl2NO4P
GABA/Glycine receptor
GABA