ChemicalBook >> CAS DataBase List >>2'-Deoxy-2'-fluorocytidine
2'-Deoxy-2'-fluorocytidine
- CAS No.
- 10212-20-1
- Chemical Name:
- 2'-Deoxy-2'-fluorocytidine
- Synonyms
- 2'-FC;2'-FdC;RO-8013;2'-F-dC;2'-FANA-C;NSC 529432;2’-F-2’-dC;2'-FLUORO-D-CYTIDINE;2'-F-2'-deoxyCytidine;2'-F-2'-deoxycytidine
- CBNumber:
- CB8670324
- Molecular Formula:
- C9H12FN3O4
- Molecular Weight:
- 245.21
- MDL Number:
- MFCD00057445
- MOL File:
- 10212-20-1.mol
Last updated:2024-07-24 10:07:30
Melting point | 167 °C |
---|---|
Boiling point | 500.1±60.0 °C(Predicted) |
Density | 1.82±0.1 g/cm3(Predicted) |
refractive index | 80 ° (C=1, MeOH) |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | Soluble in DMSO, Methanol. |
pka | 12.84±0.70(Predicted) |
form | Powder |
color | White to Off-white |
Water Solubility | Water: 5 mg/mL (20.39 mM; ultrasonic and warming and heat to 60°C) |
InChI | InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1 |
InChIKey | NVZFZMCNALTPBY-XVFCMESISA-N |
SMILES | OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](F)[C@@H]1O |
CAS DataBase Reference | 10212-20-1(CAS DataBase Reference) |
FDA UNII | LCY080JPY9 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
HS Code | 29389090 |
2'-Deoxy-2'-fluorocytidine price More Price(29)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | D3614 | 2'-Deoxy-2'-fluorocytidine Hydrate >98.0%(T) | 10212-20-1 | 1g | $68 | 2024-03-01 | Buy |
Alfa Aesar | J65632 | 2'-Fluoro-2'-deoxycytidine, 99% | 10212-20-1 | 1g | $52.65 | 2024-03-01 | Buy |
TRC | D232945 | 2’-Deoxy-2’-fluoroCytidine | 10212-20-1 | 2g | $145 | 2021-12-16 | Buy |
TRC | D232945 | 2’-Deoxy-2’-fluoroCytidine | 10212-20-1 | 10g | $525 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 33485 | 2?-Deoxy-2?-fluorocytidine 98%purewithdatedHPLCUVchromatogram | 10212-20-1 | 1mg | $685 | 2021-12-16 | Buy |
2'-Deoxy-2'-fluorocytidine Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine has been shown to inhibit Borna Disease virus replication and s pread.
in vitro
2'-Deoxy-2'-fluorocytidine has antiviral activities, showing 50% effective concentrations (EC50) of 61 nM and 31 nM against CCHFV and CCHFV/ZsG in Huh7 cells, respectively. And it shows a 50% cytotoxicity concentration (CC50) of >50.0 μM in Huh7 cells.
References
[1] Stephen R. Welch. “Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus.” Antiviral research 147 (2017): Pages 91-99.
2'-Deoxy-2'-fluorocytidine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 314)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ChemExpress | +86-021-58950125 +86-021-58950125; | info@chemexpress.com | China | 598 | 58 |
Allbiosyn Biotechnology Co.,Ltd. | +8618666985712 | info@allbiosyn.com | China | 286 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 19536 | 58 |
Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 | yunbiochem@126.com | China | 321 | 58 |
Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 | sales@unisyn.cn | CHINA | 332 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
View Lastest Price from 2'-Deoxy-2'-fluorocytidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-08 | 2'-Deoxy-2'-fluorocytidine
10212-20-1
|
US $0.00 / g | 100g | ≥98% | 20t | Hefei Huana Biomedical Technology Co.,Ltd. | ||
2023-04-04 | 2'-FLUORO-D-CYTIDINE
10212-20-1
|
US $0.00-0.00 / kg | 1kg | 98% | 500kg per month | Zhejiang Hengkang Pharmaceutical Co., Ltd. | ||
2023-03-22 | 2'-F-2'-deoxyCytidine;2‘-F-dC
10212-20-1
|
US $100.00 / kg | 0.009999999776482582kg | 99% | 5tons | SHANGHAI NOVRIBO BIOTECH |
- 2'-Deoxy-2'-fluorocytidine
10212-20-1
- US $0.00 / g
- ≥98%
- Hefei Huana Biomedical Technology Co.,Ltd.
- 2'-FLUORO-D-CYTIDINE
10212-20-1
- US $0.00-0.00 / kg
- 98%
- Zhejiang Hengkang Pharmaceutical Co., Ltd.
- 2'-F-2'-deoxyCytidine;2‘-F-dC
10212-20-1
- US $100.00 / kg
- 99%
- SHANGHAI NOVRIBO BIOTECH
2'-Deoxy-2'-fluorocytidine Spectrum
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one(10212-20-1)1HNMR4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one(10212-20-1)IR14-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one(10212-20-1)IR2
10212-20-1(2'-Deoxy-2'-fluorocytidine)Related Search:
Cytidine
4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
5'-Deoxy-5-fluorocytidine
Dmt-2'-f-dc(ac) amidite
2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate
Gemcitabine hydrochloride
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
2''-DEOXY-2''-FLUORO-5-IODOCYTIDINE
2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE
1of4
4-amino-1-[(2r,3r,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-AMINO-1-((2R,3R,4R,5R)-3-FLUORO-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDIN-2-ONE
2'-FLUORO-D-CYTIDINE
2'-DEOXY-2'-FLUOROCYTIDINE
2'-FC
2'-FLUORO-2'-DEOXYCYTIDINE
2'-FdC
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)cytosine
1-(2-Fluoro-2-deoxy-β-D-arabinofuranosyl)cytosine
RO-8013
2'-DEOXY-2'-FLUOROCYTIDINE(2'-FLUORO-2'- DEOXYCYTIDINE, 2'-FC)
2'-Deoxy-2'-fluoro-D-cytidine
2''-DEOXY-2''-FLUOROCYTIDINE,99+%
2'-Deoxy-2'-fluorocytidine Hydrate
2'-Deoxy-2'-fluorocytidine ,98%
2'-Fluoro-2'-deoxy-β-D-ribofuranosylcytosine
FN-009 2'-Fluoro-2'-deoxy-cytidine
Cytidine, 2'-deoxy-2'-fluoro-
2'-FANA-C
NSC 529432
2'-Deoxy-2'-fluorocytidine 
2'-Deoxy-2'-fluorocytidine≥ 99% (HPLC)
Fludarabine Phosphate Impurity 18
2'-Fluoro-2'-deoxycytidine, >98.0%(T)
2'-Deoxy-2'-fluorocytidineHydrate>
2’-F-2’-dC
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one USP/EP/BP
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl...
2'-F-2'-deoxyCytidine
Crimean-Congo hemorrhagic fever,2' Deoxy 2' fluorocytidine,Inhibitor,nucleoside analog,inhibit,Influenza Virus,2'Deoxy2'fluorocytidine,Antiviral,CCHFV
2'-Fluoro-2'-Deoxycytidine (FdC)
4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
2'-Fluoro-2'-Deoxycytidine
2'-Deoxy-2"-fuorocytidine
2'-F-2'-deoxycytidine
2'-Deoxy-2'-fluorocytidine
2'-F-dC
10212-20-1
110212-20-1
C9H12FN3O4xH2O
C9H12N3O4F
C9H12FN3O4
Biochemistry
Nucleosides and their analogs
Nucleosides, Nucleotides & Related Reagents
10212-20-1
Nucleosides
Modified(deoxy)nucleoside
Nucleosides-2'-F Nucleosides