S-(+)-FLUOXETINE HYDROCHLORIDE

CAS No.
114247-06-2
Chemical Name:
S-(+)-FLUOXETINE HYDROCHLORIDE
Synonyms
(S)-Fluoxetine HCl;Fluoxetine S-IsoMer;Fluoxetine HCl S-Isomer;S-(+)-FLUOXETINE HYDROCHLORIDE;N-methyl-2-phenyl-5-thiazolamine hydrochloride;Fluoxetine Impurity 14 ((S)-Fluoxetine Hydrochloride);(S)-(+)-N-Methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine HCl;(S)-N-Methyl-3-(4-trifluoroMethylphenoxy)-3-phenylpropylaMine Hydrochloride;(γS)-N-Methyl-γ-[4-(trifluoroMethyl)phenoxy]benzenepropanaMine Hydrochloride;(S)-3[4(TRIFLUOROMETHYL)PHENOXY]-N-METHYL-3-PHENYLPROPAN-1-AMINE HYDROCHLORIDE
CBNumber:
CB8674054
Molecular Formula:
C17H19ClF3NO
Molecular Weight:
345.79
MDL Number:
MFCD04040001
MOL File:
114247-06-2.mol
MSDS File:
SDS
Last updated:2023-05-26 13:35:55

S-(+)-FLUOXETINE HYDROCHLORIDE Properties

Melting point 140-142°C
storage temp. room temp
solubility H2O: 18 mg/mL, soluble
form solid
color white
Stability Hygroscopic
FDA UNII Z4S3JZC091

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H410
Precautionary statements  P264-P270-P273-P301+P312-P391-P501
Hazard Codes  Xn,N
Risk Statements  22-50/53
Safety Statements  36/37-60-61
RIDADR  UN 3077 9/PG 3
WGK Germany  3

S-(+)-FLUOXETINE HYDROCHLORIDE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F1553 S-(+)-Fluoxetine hydrochloride ≥98% (HPLC), solid 114247-06-2 5mg $187 2024-03-01 Buy
Sigma-Aldrich F1553 S-(+)-Fluoxetine hydrochloride ≥98% (HPLC), solid 114247-06-2 25mg $659 2024-03-01 Buy
TRC F597095 S-(+)-Fluoxetine hydrochloride 114247-06-2 25mg $495 2021-12-16 Buy
Product number Packaging Price Buy
F1553 5mg $187 Buy
F1553 25mg $659 Buy
F597095 25mg $495 Buy

S-(+)-FLUOXETINE HYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

A selective serotonin reuptake inhibitor (SSRI).S-(+)-Fluoxetine hydrochloride is used as an antidepressant.

Definition

ChEBI: A hydrochloride obtained by reaction of (S)-fluoxetine with one equivalent of hydrochloric acid.

General Description

Fluoxetine hydrochloride or fluoxetine hcl is a psychotropic agent and one of the initial members of the anti-depressant class of drugs known as selective serotonin-reuptake inhibitors (SSRIs). It is the active ingredient of Prozac?.

Biochem/physiol Actions

Fluoxetine hcl (hydrochloride) is a selective serotonin reuptake inhibitor and functions as an antidepressant. This drug works at presynaptic terminals where it prevents the reuptake of serotonin, resulting in the accumulation of serotonin in extracellular fluid at synapses.

114133-37-8
98-56-6
114247-06-2
Synthesis of S-(+)-FLUOXETINE HYDROCHLORIDE from (s)-3-(methylamino)-1-phenylpropanol (114133-37-8) and 4-Chlorobenzotrifluoride

S-(+)-FLUOXETINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-N-Methyl-3-(4-trifluoroMethylphenoxy)-3-phenylpropylaMine Hydrochloride (γS)-N-Methyl-γ-[4-(trifluoroMethyl)phenoxy]benzenepropanaMine Hydrochloride Fluoxetine S-IsoMer S-(+)-FLUOXETINE HYDROCHLORIDE (S)-3[4(TRIFLUOROMETHYL)PHENOXY]-N-METHYL-3-PHENYLPROPAN-1-AMINE HYDROCHLORIDE (S)-(+)-N-Methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine HCl N-methyl-2-phenyl-5-thiazolamine hydrochloride (S)-Fluoxetine HCl Fluoxetine HCl S-Isomer Fluoxetine Impurity 14 ((S)-Fluoxetine Hydrochloride) 114247-06-2 Biogenic Amine Transport Inhibitors Biogenic Amine Transport InhibitorsObesity Research Neurotransmission Neurotransmission (Obesity) Neurotransmitters Amines Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals