Pargyline
- CAS No.
- 555-57-7
- Chemical Name:
- Pargyline
- Synonyms
- MO 911;A 19120;Eudatin;Eutonyl;Supirdyl;Pargylin;PARGYLINE;Paragyline;Pargylamine;AURORA KA-7798
- CBNumber:
- CB8698159
- Molecular Formula:
- C11H13N
- Molecular Weight:
- 159.23
- MDL Number:
- MFCD00008576
- MOL File:
- 555-57-7.mol
- MSDS File:
- SDS
| Melting point | 15-20 °C |
|---|---|
| Boiling point | 86-88 °C4 mm Hg(lit.) |
| Density | 0.944 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 183 °F |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Liquid |
| pka | pKa 6.9 (Uncertain) |
| color | Clear yellow |
| Merck | 14,7038 |
| EWG's Food Scores | 1 |
| FDA UNII | 9MV14S8G3E |
| ATC code | C02KC01 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P310-P302+P352+P312-P304+P340+P311-P305+P351+P338 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/24/25-36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-45-23 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DP6475000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29214900 | |||||||||
| NFPA 704 |
|
Pargyline price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M74253 | N-Methyl-N-propargylbenzylamine 97% | 555-57-7 | 5g | $145 | 2024-03-01 | Buy |
| Sigma-Aldrich | M74253 | N-Methyl-N-propargylbenzylamine 97% | 555-57-7 | 25g | $570 | 2024-03-01 | Buy |
| TCI Chemical | M2618 | N-Methyl-N-propargylbenzylamine >98.0%(GC)(T) | 555-57-7 | 1g | $154 | 2024-03-01 | Buy |
| TCI Chemical | M2618 | N-Methyl-N-propargylbenzylamine >98.0%(GC)(T) | 555-57-7 | 5g | $629 | 2021-12-16 | Buy |
| Chem-Impex | 38066 | Pargyline,≥98%(Assaybytitration,GC)Hazmat ≥98%(Assaybytitration,GC) | 555-57-7 | 5G | $686.07 | 2021-12-16 | Buy |
Pargyline Chemical Properties,Uses,Production
Chemical Properties
CLEAR YELLOW LIQUID
Originator
Eutonyl, Abbott , US ,1963
Uses
analgesic
Definition
ChEBI: Pargyline is an aromatic amine.
Manufacturing Process
A mixture of 23.8 grams (0.2 mol) of propargyl bromide, 24.2 grams (0.2 mol) of N-methylbenzylamine and 400 ml of anhydrous ethanol in the presence of 42.4 grams (0.4 mol) of anhydrous sodium carbonate was heated at the boiling temperature and under reflux for a period of 17 hours.
The sodium carbonate was then removed by filtration and the alcohol was removed by distillation under reduced pressure. The residue was treated with 300 ml of dry ether and the resulting solution was filtered to remove sodium bromide.
The filtrate was dried and fractionally distilled under reduced pressure to obtain the desired N-methyl-N-propargylbenzylamine which boiled at 96°97°C at 11 mm pressure.
Analysis calculated for C11H13N: C = 82.97%; H = 8.23%; N = 8.80%. Found: C = 82.71%; H = 8.51%; N = 8.93%.
The hydrochloride salt of this amine was prepared by dissolving the amine in ether and adding ethereal hydrogen chloride to the ether solution. The solid hydrochloride salt which precipitated was recrystallized from an ethanol-ether mixture and was found to melt at 154° - 155°C.
brand name
Eutonyl (Abbott).
Therapeutic Function
Antihypertensive
Enzyme inhibitor
This antihypertensive agent (FWfree-base = 159.23 g/mol; CAS 555-57-7), also known as Eutonyl, N-benzyl-N-methyl-2-propynylamine, is amechanism-based inhibitor that targets monoamine oxidase, beginning with an initial reversible interaction (Ki = 4-5 μM) and proceeding to irreversible loss of enzyme activity. Target(s): aldehyde dehydrogenase, pargyline is the precursor of the actual inhibitor; bacterial bioluminescence; and monoamine oxidase.
Pargyline Preparation Products And Raw materials
Raw materials
Preparation Products
Pargyline Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12477 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9409 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29322 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 | market03@meryer.com | China | 40241 | 62 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12990 | 57 |
View Lastest Price from Pargyline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-11 | Pargyline USP/EP/BP
555-57-7
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-10 | Pargyline
555-57-7
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
-
- Pargyline USP/EP/BP
555-57-7
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Pargyline
555-57-7
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
555-57-7(Pargyline)Related Search:
1of4