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1-Bromo-3-chloropropane

1-Bromo-3-chloropropane
1-Bromo-3-chloropropane structure
CAS No.
109-70-6
Chemical Name:
1-Bromo-3-chloropropane
Synonyms
I-BCP;NSC 9183;1,3-Chbp;ω-Chlorobr;CHLOROBROMOPROPANE;BROMOCHLOROPROPANE;1-Bromo-3-chloroprop;1-Brom-3-chlorpropan;1,3-chlorbromopropane;trimethylenbromchlorid
CBNumber:
CB8700201
Molecular Formula:
C3H6BrCl
Formula Weight:
157.44
MOL File:
109-70-6.mol

1-Bromo-3-chloropropane Properties

Melting point:
-59 °C
Boiling point:
144-145 °C(lit.)
Density 
1.592 g/mL at 25 °C(lit.)
vapor pressure 
7.5 hPa (20 °C)
refractive index 
n20/D 1.486(lit.)
Flash point:
81 °C
storage temp. 
room temp
solubility 
2.24g/l insoluble
form 
liquid
explosive limit
3.2-8.6%(V)
Water Solubility 
insoluble
BRN 
605278
CAS DataBase Reference
109-70-6(CAS DataBase Reference)
NIST Chemistry Reference
Propane, 1-bromo-3-chloro-(109-70-6)
EPA Substance Registry System
Propane, 1-bromo-3-chloro-(109-70-6)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  10-22-36/37/38-20/21/22-20/22-68-52/53-37
Safety Statements  16-45-36/37/39-26
RIDADR  UN 2688 6.1/PG 3
WGK Germany  3
RTECS  TX4113000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29034980
Hazardous Substances Data 109-70-6(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 1100 - 1200 mg/kg LD50 dermal Rat > 2000 mg/kg
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H402 Harmful to aquatic life Hazardous to the aquatic environment, acute hazard Category 3
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

1-Bromo-3-chloropropane price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B62404 1-Bromo-3-chloropropane 99% 109-70-6 250g $30.2 2018-11-13 Buy
Sigma-Aldrich B62404 1-Bromo-3-chloropropane 99% 109-70-6 1kg $79.7 2018-11-13 Buy
TCI Chemical B0575 1-Bromo-3-chloropropane >99.0%(GC) 109-70-6 25g $14 2018-11-22 Buy
TCI Chemical B0575 1-Bromo-3-chloropropane >99.0%(GC) 109-70-6 500g $42 2018-11-22 Buy
Alfa Aesar A11395 1-Bromo-3-chloropropane, 99% 109-70-6 100g $16 2018-11-13 Buy

1-Bromo-3-chloropropane Chemical Properties,Uses,Production

Chemical Properties

clear liquid

Uses

1-Bromo-3-chloropropane can be used safer and equally efficient alternative to chloroform as a phase-separation agent in the 1-step method of RNA isolation from biological samples such as animal and p lant tissue.

Uses

A replacement for CHCl3 in RNA phase separations

General Description

A colorless liquid. Insoluble in water and denser than water. May be toxic by inhalation, ingestion or skin absorption. Used to make pharmaceuticals and other chemicals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Halogenated aliphatic compounds, such as 1-Bromo-3-chloropropane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Health Hazard

Inhalation of vapors or dust is extremely irritating. May cause burning of eyes and flow of tears. May cause coughing, difficult breathing and nausea. Brief exposure effects last only a few minutes. Exposure in an enclosed area may be very harmful. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Some of these materials may burn, but none ignite readily. Containers may explode when heated.

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of Cland Br-. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and BROMIDES.

Purification Methods

Wash it with conc H2SO4, water, 10% Na2CO3 solution, water again and then dry with CaCl2 and fractionally distil it just before use [Akagi et al. J Am Chem Soc 78 4034 1956]. [Beilstein 1 H 109, 1 IV 212.]

1-Bromo-3-chloropropane Preparation Products And Raw materials

Raw materials

Preparation Products


1-Bromo-3-chloropropane Suppliers

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1-Bromo-3-chloropropane Spectrum


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