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3-Nitro-L-tyrosine

3-Nitro-L-tyrosine structure

CAS No.: 621-44-3

Chemical Name:: 3-Nitro-L-tyrosine

Synonyms: 3-NITRO-TYROSINE;NITROTYROSINE;H-TYR(3-NO2)-OH;Tyr(3'-NO2);Z-D-Dap(Boc);H-TYR(M-NO2)-OH;m-Nitro-L-Tyr-OH;H-3-NITRO-TYR-OH;H-M-NITRO-TYR-OH;M-NITRO-L-TYROSINE

CBNumber:: CB8703176

Molecular Formula:: C9H10N2O5

Molecular Weight:: 226.19

MDL Number:: MFCD00007123

MOL File:: 621-44-3.mol

MSDS File:: SDS

Last updated:2025-11-11 10:47:11

Product description	Number	Pack Size	Price
3-Nitro-L-tyrosine crystalline	N7389	5g	$129
3-Nitro-L-tyrosine crystalline	N7389	10g	$170.1
3-Nitro-L-tyrosine >98.0%(HPLC)(T)	N0905	5g	$182
3-Nitro-L-tyrosine >98.0%(HPLC)(T)	N0905	25g	$652
3-Nitro-L-tyrosine crystalline	N7389	25g	$512
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3-Nitro-L-tyrosine Properties

Melting point	233-235 °C (dec.) (lit.)
alpha	4 º (c=1, 1N HCl)
Boiling point	367.79°C (rough estimate)
Density	1.4160 (rough estimate)
refractive index	1.5373 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Aqueous Acid (Slightly), Water
pka	2.17±0.20(Predicted)
form	crystalline
color	yellow to green
Water Solubility	insoluble
BRN	2813157
InChI	InChI=1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1
InChIKey	FBTSQILOGYXGMD-LURJTMIESA-N
SMILES	C(O)(=O)[C@H](CC1=CC=C(O)C([N+]([O-])=O)=C1)N
CAS DataBase Reference	621-44-3(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	7COY1HA6HK
UNSPSC Code	12352200
NACRES	NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P280-P302+P352-P362+P364

Hazard Codes

Risk Statements

36/37/38

Safety Statements

24/25-37/39-26-36

WGK Germany

HS Code

29225090

NFPA 704

	1
2		0

3-Nitro-L-tyrosine price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	N7389	3-Nitro-L-tyrosine crystalline	621-44-3	5g	$129	2025-07-31	Buy
Sigma-Aldrich	N7389	3-Nitro-L-tyrosine crystalline	621-44-3	10g	$170.1	2025-07-31	Buy
TCI Chemical	N0905	3-Nitro-L-tyrosine >98.0%(HPLC)(T)	621-44-3	5g	$182	2025-07-31	Buy
TCI Chemical	N0905	3-Nitro-L-tyrosine >98.0%(HPLC)(T)	621-44-3	25g	$652	2025-07-31	Buy
Sigma-Aldrich	N7389	3-Nitro-L-tyrosine crystalline	621-44-3	25g	$512	2025-07-31	Buy

Product number	Packaging	Price	Buy
N7389	5g	$129	Buy
N7389	10g	$170.1	Buy
N0905	5g	$182	Buy
N0905	25g	$652	Buy
N7389	25g	$512	Buy

3-Nitro-L-tyrosine Chemical Properties,Uses,Production

Description

Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo. Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions. The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by gas chromatography/mass spectrometry.

Chemical Properties

ochre-yellow to yellow-green powder

Uses

3-Nitro-L-tyrosine is used as an indicator of the formation of peroxynitrite by NO-dependent oxidative damage.

Uses

A marker for peroxynitrite. Oxidant and cytotoxic agent.

Definition

ChEBI: 3-nitro-L-tyrosine is a 3-nitrotyrosine comprising L-tyrosine having a nitro group at the 3-position on the phenyl ring. It is a L-tyrosine derivative, a non-proteinogenic L-alpha-amino acid and a 3-nitrotyrosine. It is an enantiomer of a 3-nitro-D-tyrosine.

Biochem/physiol Actions

Oxidant and cytotoxic agent.

References

[1] J S BECKMAN W H K. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly.[J]. American Journal of Physiology, 1996, 271 5 Pt 1: C1424-37. DOI: 10.1152/ajpcell.1996.271.5.c1424
[2] J S BECKMANN. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry.[J]. Biological chemistry Hoppe-Seyler, 1994, 375 2: 81-88. DOI: 10.1515/bchm3.1994.375.2.81
[3] K ABE. Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis.[J]. Neurological Research, 1997, 19 2: 124-128. DOI: 10.1080/01616412.1997.11740784
[4] ROBERT J. FERRANTE PHD. Leslie A S PhD, MD. Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation[J]. Annals of Neurology, 2004, 42 3: 326-334. DOI: 10.1002/ana.410420309
[5] I Y HADDAD. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.[J]. Journal of Clinical Investigation, 1994, 94 6: 2407-2413. DOI: 10.1172/jci117607
[6] M. OHYA. Plasma Nitrotyrosine Concentration Relates to Prognosis in Human Septic Shock[J]. SHOCK, 2002, 18 1: 116-118. DOI: 10.1097/00024382-200208000-00004
[7] DIMITRIOS TSIKAS. Accurate quantification of basal plasma levels of 3-nitrotyrosine and 3-nitrotyrosinoalbumin by gas chromatography–tandem mass spectrometry[J]. Journal of Chromatography B, 2003, 784 1: Pages 77-90. DOI: 10.1016/s1570-0232(02)00751-1
[8] EDZARD SCHWEDHELM. Gas Chromatographic–Tandem Mass Spectrometric Quantification of Free 3-Nitrotyrosine in Human Plasma at the Basal State[J]. Analytical biochemistry, 1999, 276 2: Pages 195-203. DOI: 10.1006/abio.1999.4361
[9] JIAN LIU Steven G L. High-fat, low-carbohydrate diet alters myocardial oxidative stress and impairs recovery of cardiac function after ischemia and reperfusion in obese rats[J]. Nutrition Research, 2013, 33 4: Pages 311-321. DOI: 10.1016/j.nutres.2013.02.005

3-Nitro-L-tyrosine Preparation Products And Raw materials

Raw materials

Preparation Products

3-Nitro-L-tyrosine Suppliers

Global( 258)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32435	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
GenicBio Limited	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
GL Biochem (Shanghai) Ltd.	58

View Lastest Price from 3-Nitro-L-tyrosine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-10	3-Nitro-L-tyrosine 621-44-3	US $40.00 / mg		99.54%	10g	TargetMol Chemicals Inc.

3-Nitro-L-tyrosine
621-44-3
US $40.00 / mg
99.54%
TargetMol Chemicals Inc.

3-Nitro-L-tyrosine Spectrum

3-Nitro-L-tyrosine(621-44-3)MS 3-Nitro-L-tyrosine(621-44-3)¹HNMR 3-Nitro-L-tyrosine(621-44-3)¹³CNMR 3-Nitro-L-tyrosine(621-44-3)IR1 3-Nitro-L-tyrosine(621-44-3)IR2 3-Nitro-L-tyrosine(621-44-3)Raman

621-44-3(3-Nitro-L-tyrosine)Related Search:

H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH L-Tyrosine Boc-D-Tyr-OH 3-NITRO-L-TYROSINE ETHYL ESTER HYDROCHLORIDE 3,5-DINITRO-L-TYROSINE MONOHYDRATE

N-Acetyl-3,5-dinitro-L-tyrosine NITROGEN DIOXIDE FMOC-3-NITRO-L-TYROSINE,N-ALPHA-FMOC-3-NITRO-L-TYROSINE,NALPHA-9-Fluorenylmethoxycarbonyl-3-nitro-L-tyrosine 3,5-DINITRO-L-TYROSINE MONOHYDRATE, 97 3-NITRO-D-TYROSINE

FMOC-3,5-DINITRO-TYR-OH BOC-TYR(BZL, 3-NO2)-OH N-ACETYL-L-3-NITROTYROSINE ETHYL ESTER (S)-2-AMINO-3-(4-HYDROXY-3-NITRO-PHENYL)-PROPIONIC ACID METHYL ESTER 3,5-DINITRO-L-TYROSINE SODIUM SALT

AC-3,5-DINITRO-TYR-OET BOC-3-NITRO-L-TYROSINE ABZ-SER-PRO-3-NITRO-TYR-OH

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(2R)-2-Amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid L-Tyrosine, 3-nitro- 3-Nitro-L-tyrosine,99% (S)-2-aMino-3-(4-hydroxy-3-nitrophenyl)propanoic acid Z-D-Dap(Boc) 3-NITRO-L-TYROSINE (RING-13C6) (S)-3-(3-Nitro-4-hydroxyphenyl)alanine 3-Nitro-L-tyrosine≥ 98% (Assay) m-Nitro-L-Tyr-OH M-NITRO-L-TYROSINE 3-NITRO-4-HYDROXY-PHENYLALANINE 3-NITRO-L-TYROSINE Tyr(3'-NO2) 3-NITRO-TYROSINEH-TYR(3-NO2)-OH 3-Nitro-L-tyrosine 99% H-TYR(M-NO2)-OH H-4-HYDROXY-3-NITRO-PHE-OH H-3-NITRO-L-TYROSINE H-3-NITRO-TYR-OH H-M-NITRO-TYR-OH (2S)-2-ammonio-3-(3-nitro-4-oxidophenyl)propanoate 3-Nitro-L-tyrosine> 3-Nitro-L-tyrosine USP/EP/BP H-TYR(3-NO2)-OH NITROTYROSINE 3-NITRO-TYROSINE 3-Nitro-L-tyrosine, ≥ 98.0% Rabbit Anti-3-Nitrotyrosine antibody 3-Nitro-L-tyrosine 3-Nitrotyrosine Rabbit pAb 621-44-3 O2NC6H34OHCH2CHNH2CO2H C9H9N2O5 Unnatural Amino Acid Derivatives Tyrosine Derivatives Specialty Synthesis Peptide Synthesis Pharmaceutical Raw Materials Amino Acids Tyrosine [Tyr, Y] Unusual Amino Acids Oxidative Stress Proteins and ReagentsPeptide Synthesis Cell Stress Nitric Oxide and Cell Stress Amino Acids & Derivatives Aromatics Peptide Synthesis Tyrosine Derivatives Unnatural Amino Acid Derivatives