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3-Nitro-L-tyrosine

CAS No.
621-44-3
Chemical Name:
3-Nitro-L-tyrosine
Synonyms
3-NITRO-TYROSINE;NITROTYROSINE;H-TYR(3-NO2)-OH;Tyr(3'-NO2);Z-D-Dap(Boc);H-TYR(M-NO2)-OH;m-Nitro-L-Tyr-OH;H-3-NITRO-TYR-OH;H-M-NITRO-TYR-OH;M-NITRO-L-TYROSINE
CBNumber:
CB8703176
Molecular Formula:
C9H10N2O5
Molecular Weight:
226.19
MDL Number:
MFCD00007123
MOL File:
621-44-3.mol
MSDS File:
SDS
Last updated:2023-05-18 11:30:58

3-Nitro-L-tyrosine Properties

Melting point 233-235 °C (dec.) (lit.)
alpha 4 º (c=1, 1N HCl)
Boiling point 367.79°C (rough estimate)
Density 1.4160 (rough estimate)
refractive index 1.5373 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Aqueous Acid (Slightly), Water
form crystalline
pka 2.17±0.20(Predicted)
color yellow to green
Water Solubility insoluble
BRN 2813157
CAS DataBase Reference 621-44-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 7COY1HA6HK

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P302+P352-P362+P364
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-37/39-26-36
WGK Germany  3
HS Code  29225090
NFPA 704
1
2 0

3-Nitro-L-tyrosine price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N7389 3-Nitro-L-tyrosine crystalline 621-44-3 5g $125 2024-03-01 Buy
Sigma-Aldrich N7389 3-Nitro-L-tyrosine crystalline 621-44-3 10g $236 2024-03-01 Buy
TCI Chemical N0905 3-Nitro-L-tyrosine >98.0%(HPLC)(T) 621-44-3 5g $183 2024-03-01 Buy
TCI Chemical N0905 3-Nitro-L-tyrosine >98.0%(HPLC)(T) 621-44-3 25g $656 2024-03-01 Buy
Alfa Aesar A11018 3-Nitro-L-tyrosine, 98% 621-44-3 5g $44.8 2023-06-20 Buy
Product number Packaging Price Buy
N7389 5g $125 Buy
N7389 10g $236 Buy
N0905 5g $183 Buy
N0905 25g $656 Buy
A11018 5g $44.8 Buy

3-Nitro-L-tyrosine Chemical Properties,Uses,Production

Description

Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo. Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions. The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by gas chromatography/mass spectrometry.

Chemical Properties

ochre-yellow to yellow-green powder

Uses

3-Nitro-L-tyrosine is used as an indicator of the formation of peroxynitrite by NO-dependent oxidative damage.

Uses

A marker for peroxynitrite. Oxidant and cytotoxic agent.

Definition

ChEBI: 3-nitro-L-tyrosine is a 3-nitrotyrosine comprising L-tyrosine having a nitro group at the 3-position on the phenyl ring. It is a L-tyrosine derivative, a non-proteinogenic L-alpha-amino acid and a 3-nitrotyrosine. It is an enantiomer of a 3-nitro-D-tyrosine.

Biochem/physiol Actions

Oxidant and cytotoxic agent.

3-Nitro-L-tyrosine Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R)-2-Amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid L-Tyrosine, 3-nitro- 3-Nitro-L-tyrosine,99% (S)-2-aMino-3-(4-hydroxy-3-nitrophenyl)propanoic acid Z-D-Dap(Boc) 3-NITRO-L-TYROSINE (RING-13C6) (S)-3-(3-Nitro-4-hydroxyphenyl)alanine 3-Nitro-L-tyrosine≥ 98% (Assay) m-Nitro-L-Tyr-OH M-NITRO-L-TYROSINE 3-NITRO-4-HYDROXY-PHENYLALANINE 3-NITRO-L-TYROSINE Tyr(3'-NO2) 3-NITRO-TYROSINEH-TYR(3-NO2)-OH 3-Nitro-L-tyrosine 99% H-TYR(M-NO2)-OH H-4-HYDROXY-3-NITRO-PHE-OH H-3-NITRO-L-TYROSINE H-3-NITRO-TYR-OH H-M-NITRO-TYR-OH (2S)-2-ammonio-3-(3-nitro-4-oxidophenyl)propanoate 3-Nitro-L-tyrosine> 3-Nitro-L-tyrosine USP/EP/BP H-TYR(3-NO2)-OH NITROTYROSINE 3-NITRO-TYROSINE Rabbit Anti-3-Nitrotyrosine antibody 3-Nitro-L-tyrosine, ≥ 98.0% 621-44-3 O2NC6H34OHCH2CHNH2CO2H C9H9N2O5 Unnatural Amino Acid Derivatives Tyrosine Derivatives Specialty Synthesis Peptide Synthesis Pharmaceutical Raw Materials Amino Acids Tyrosine [Tyr, Y] Unusual Amino Acids Oxidative Stress Proteins and ReagentsPeptide Synthesis Cell Stress Nitric Oxide and Cell Stress Amino Acids & Derivatives Aromatics Peptide Synthesis Tyrosine Derivatives Unnatural Amino Acid Derivatives