ChemicalBook >> CAS DataBase List >>Clobetasol
Clobetasol
- CAS No.
- 25122-41-2
- Chemical Name:
- Clobetasol
- Synonyms
- CLOBETASOLE PROPIONATE;CLOBETASOL-17-PROPIONATE;Clobetasol;ClobetasolBase;Clobetasol USP/EP/BP;Clobetasol Impurity G;CLOBESTASOL PROPIONATE;Betamethasone Impurity B;Clobetasol impurity G (PhEur);Clobetasol Propionate EP IMP G
- CBNumber:
- CB8715108
- Molecular Formula:
- C22H28ClFO4
- Molecular Weight:
- 410.91
- MDL Number:
- MFCD03695616
- MOL File:
- 25122-41-2.mol
Last updated:2024-04-01 18:08:31
| Melting point | 220-222°C |
|---|---|
| Boiling point | 555.1±50.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Acetone (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.03±0.70(Predicted) |
| color | White to Light Brown |
| FDA UNII | ADN79D536H |
| ATC code | D07AD01 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360Df-H373-H413 |
| Precautionary statements | P201-P308+P313 |
| Hazard Codes | T |
| Risk Statements | 61-48/20/21-53-62 |
| Safety Statements | 53-36/37-45 |
Clobetasol price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C583490 | Clobetasol | 25122-41-2 | 100mg | $1210 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024630 | CLOBETASOL 95.00% | 25122-41-2 | 100MG | $1758.49 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 68820 | Clobetasol | 25122-41-2 | 100mg | $2000 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 68820 | Clobetasol | 25122-41-2 | 10mg | $625 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024630 | CLOBETASOL 95.00% | 25122-41-2 | 10MG | $697.34 | 2021-12-16 | Buy |
Clobetasol Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Solid
Originator
Dermovate,Glaxo,UK,1973
Uses
Atorvastatin Intermediate
Uses
Clobetasol (Clobetasol Propionate EP Impurity G) is a topical corticosteroid. Glucocorticoid; anti-inflammatory.
Definition
ChEBI: A 3-oxo-Delta1,Delta4-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha posit ons, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.
Manufacturing Process
A solution of betamethasone 21-methanesulfonate (4 g) in dimethylformamide
(25 ml) was treated with lithium chloride (4 g) and the mixture heated on the
steam bath for 30 minutes. Dilution with water gave the crude product which
was recrystallized to afford the title compound, MP 226°C.
Clobetasol is usually converted to the propionate as the useful form by
reaction with propionic anhydride.
brand name
Clobex (Galderma); Clobex (Galderma); Embeline (Healthpoint); Olux (Connetics); Temovate (Altana).
Therapeutic Function
Corticosteroid, Antiinflammatory
Clobetasol Preparation Products And Raw materials
Global( 142)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9604 | 58 |
View Lastest Price from Clobetasol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | Betamethasone EP Impurity B
25122-41-2
|
US $0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
 |
2024-04-02 | Betamethasone EP Impurity B
25122-41-2
|
US $0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
 |
2023-11-16 | Clobetasol
25122-41-2
|
US $0.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- Betamethasone EP Impurity B
25122-41-2
- US $0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- Betamethasone EP Impurity B
25122-41-2
- US $0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- Clobetasol
25122-41-2
- US $0.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
25122-41-2(Clobetasol)Related Search:
Betamethasone-17-ketone
Betamethasone EP Impurity D
Betamethasone Impurity 35
11-Oxo-betaMethasone Dipropionate
Mometasone furoate
Trimethyl borate
Dexamethasone
9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione
Ethanone, 2-chloro-1-cyclopentyl- (9CI)
CLOBETASOL PROPIONATE RELATED COMPOUND A (50 MG) (9-ALPHA-FLUORO-11-BETA-HYDROXY-16-BETA-METHYL-3-OXO-ANDROSTA-1,4-DIENE-17(R)-SPIRO-2'-[4'-CHLORO-5'-ETHYLFURAN-3'(2'H)-ONE])
Halobetasol propionate
Clobetasol propionate
CLOBETASOL FOR PEAK IDENTIFICATION,CLOBETASOL FOR PEAK IDENTIFICATION
CLOBETASOL IMPURITY J,CLOBETASOL IMPURITY J
1of4
ClobetasolBase
Clobetasol Propionate 25122-46-7 / Base
21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
CLOBESTASOL PROPIONATE
Clobetasol (Betamethasone Impurity B)
(11β,16β)-21-Chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
Clobetasol impurity G (PhEur)
17-(2-Chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8, 11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Clobetasol
Clobetasol Propionate Impurity 7(Clobetasol Propionate EP Impurity G)
Clobetasol (Betamethasone EP Impurity B)
Clobetasol Propionate EP Impurity G
Clobetasol Impurity G
Betamethasone Impurity 2（Betamethasone EP Impurity B）
Betamethasone impurity 1/Betamethasone EP Impurity B/Clobetasol/21-Chloro-9-fluoro-11?,17-dihydroxy-16?-methylpregna-1,4-diene-3,20-dione
Clobetasol Propionate EP IMP G
21-Chloro-9-fluoro-11beta,17-dihydr
Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16β)-
Clobetasol Propionate EP Impurity G/Betamethasone EP Impurity B
Clobetasol USP/EP/BP
Clobetasol (1.0 mg/mL in Methanol)
Betamethasone Impurity B
Betamethasone Impurity B (EP)/ Clobetasol Propionate Impurity-G (EP)
Clobetasol Propionate Impurity-G (EP)/ Betamethasone Impurity B (EP)
Clobetasol D5Q: What is
Clobetasol D5 Q: What is the CAS Number of
Clobetasol D5 Q: What is the storage condition of
Clobetasol D5 Q: What are the applications of
Clobetasol D5
21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
CLOBETASOLE PROPIONATE
CLOBETASOL-17-PROPIONATE
(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Clobetasol Propionate Impurity G
Betamethasone EP Impurity B（Clobetasol Propionate EP Impurity G）
Clobetasol (Betamethasone EP Impurity B, Clobetasol Propionate EP Impurity G)
1, 4-PREGNADIEN-21-CHLORO-9α-FLUORO-16β-METHYL-11β, 17α-DIOL-3, 20-DIONE
21-chloro-9-uoro-11β,17-dihydroxy-16β-methylpregna- 1,4-diene-3,20-dione
25122-41-2
C22H28ClFO4
CI - CL
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