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BENZAMIDINE

CAS No.
618-39-3
Chemical Name:
BENZAMIDINE
Synonyms
benziMidaMide;phenylamidine;BENZAMIDINE;benzylamidine;EINECS 210-546-3;Phenylmethanamidine;benzenecarbonamidine;BENZENECARBOXIMIDAMIDE;α-Iminobenzenemethanamine
CBNumber:
CB8718710
Molecular Formula:
C7H8N2
Molecular Weight:
120.15
MDL Number:
MFCD00042826
MOL File:
618-39-3.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:40

BENZAMIDINE Properties

Melting point 65-70 °C
Boiling point 208.5±23.0 °C(Predicted)
Density 1.09±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
pka 11.90±0.40(Predicted)
form powder or crystals
color White to Off-White
BRN 606020
FDA UNII KUE3ZY3J1F

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
WGK Germany  3
9-23
HS Code  29299000

BENZAMIDINE price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 12072 Benzamidine ≥95.0% 618-39-3 10g $297 2024-03-01 Buy
Sigma-Aldrich 12072 Benzamidine ≥95.0% 618-39-3 50g $999 2024-03-01 Buy
TRC B130203 Benzamidine 618-39-3 250mg $70 2021-12-16 Buy
Biosynth Carbosynth FB35345 Benzamidine 618-39-3 1g $80 2021-12-16 Buy
Biosynth Carbosynth FB35345 Benzamidine 618-39-3 500mg $50 2021-12-16 Buy
Product number Packaging Price Buy
12072 10g $297 Buy
12072 50g $999 Buy
B130203 250mg $70 Buy
FB35345 1g $80 Buy
FB35345 500mg $50 Buy

BENZAMIDINE Chemical Properties,Uses,Production

Uses

Benzamidine was used in the preparation of heparan sulfate-rich proteoglycan from mouse mammary epithelial cells. It has been used to prevent enzymatic degradation during the purification procedure of bovine factor XII (Hageman factor).

Definition

ChEBI: Benzamidine is a carboxamidine that is benzene carrying an amidino group. It has a role as a serine protease inhibitor. It is a member of benzenes and a carboxamidine. It is functionally related to a benzoic acid. It is a conjugate base of a benzamidine(1+).

Synthesis Reference(s)

The Journal of Organic Chemistry, 27, p. 1255, 1962 DOI: 10.1021/jo01051a033
Tetrahedron Letters, 31, p. 1969, 1990 DOI: 10.1016/S0040-4039(00)88891-7

Biochem/physiol Actions

Benzamidine is an inhibitor of plasmin and has been used in the radioimmunoassay of glucagon in human plasma. It prevents the destruction of Thyrotropin-releasing hormone (TRH) added to whole blood in vitro before radioimmunoassay of TRH.

Purification Methods

It is liberated from its hydrochloride chloride (below) by treatment with 5M NaOH, extracted into diethyl ether, dried (Na2SO4) and sublimed in vacuo.[Beilstein 9 H 280, 9 I 123, 9 II 199, 9 1264, 9 IV 898.]

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View Lastest Price from BENZAMIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BENZAMIDINE pictures 2021-07-13 BENZAMIDINE
618-39-3
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
BENZAMIDINE pictures 2021-07-10 BENZAMIDINE
618-39-3
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
BENZAMIDINE pictures 2019-07-06 BENZAMIDINE
618-39-3
US $1.00 / kg 1kg 95%-99% 100kg Career Henan Chemical Co
  • BENZAMIDINE pictures
  • BENZAMIDINE
    618-39-3
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • BENZAMIDINE pictures
  • BENZAMIDINE
    618-39-3
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • BENZAMIDINE pictures
  • BENZAMIDINE
    618-39-3
  • US $1.00 / kg
  • 95%-99%
  • Career Henan Chemical Co
BENZENECARBOXIMIDAMIDE EINECS 210-546-3 benzenecarbonamidine benzylamidine Phenylmethanamidine α-Iminobenzenemethanamine BENZAMIDINE phenylamidine benziMidaMide 618-39-3 C6H5CNH2NH C6H5CNHNH2 Building Blocks Nitrogen Compounds Imines/Amidines Organic Building Blocks pharmacetical Imines/Amidines Nitrogen Compounds Organic Building Blocks B Bioactive Small Molecules Building Blocks Cell Biology Chemical Synthesis Nitrogen Compounds Organic Building Blocks