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FURIN INHIBITOR II

CAS No.
673202-67-0
Chemical Name:
FURIN INHIBITOR II
Synonyms
H-(D)RRRRRR-NH2;HEXA-D-ARGININE;FURIN INHIBITOR II;Hexa-D-arginine aMide;Hexa-D-arginine,RRRRRR;Furin Inhibitor II, >98%;Furin Inhibitor II(Hexa-D-arginine);H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2;D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-;D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI)
CBNumber:
CB8719126
Molecular Formula:
C36H75N25O6
Molecular Weight:
954.14
MDL Number:
MFCD04974168
MOL File:
673202-67-0.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

FURIN INHIBITOR II Properties

Density 1.59±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility H2O : 50 mg/mL (52.40 mM; Need ultrasonic)DMSO : 5 mg/mL (5.24 mM; Need ultrasonic)
pka 13.24±0.46(Predicted)
form lyophilized
Water Solubility Soluble to 2 mg/ml in water

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
WGK Germany  3

FURIN INHIBITOR II price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SCP0148 Furin Inhibitor II 673202-67-0 5MG $268 2023-06-20 Buy
Tocris 4711 Hexa-D-arginine 673202-67-0 1 $124 2021-12-16 Buy
Usbiological 145676 Hexa-D-arginine 673202-67-0 1mg $375 2021-12-16 Buy
TRC H951018 Hexa-D-arginine 673202-67-0 1mg $115 2021-12-16 Buy
ApexBio Technology B5692 (R)-2-amino-5-((diaminomethylene)amino)-N-((6R,9R,12R,15R,18R)-1,1,23,23-tetraamino-6-carbamoyl-9,12,15-tris(3-((diaminomethylene)amino)propyl)-8,11,14,17-tetraoxo-2,7,10,13,16,22-hexaazatricosa-1,22-dien-18-yl)pentanamide 673202-67-0 10mg $1020 2021-12-16 Buy
Product number Packaging Price Buy
SCP0148 5MG $268 Buy
4711 1 $124 Buy
145676 1mg $375 Buy
H951018 1mg $115 Buy
B5692 10mg $1020 Buy

FURIN INHIBITOR II Chemical Properties,Uses,Production

Uses

Furin Inhibitor II has been used as a furin inhibitor:

  • to study its effects on transforming growth factor β1 (TGF-β1) induced glial cell line-derived neurotrophic factor (GDNF) production in non-tumorigenic immortalized human granulosa cell line (SVOG).
  • to study its effect on cleavage of (Pro) renin receptor (PRR) induced by bovine serum albumin (BSA) in human kidney 2 (HK-2) cells.
  • in furin cleavage assay.

General Description

Furin is a calcium-dependent serine endoproteinase and belongs to the subtilisin-like proprotein/prohormone convertase (PC) family. It is distributed ubiquitously and has a rhythmic movement between the trans-Golgi network, cell surface and the endosomes.

Biochem/physiol Actions

Furin plays a role in processing several pro-proteins such as, bone morphogenetic protein?4 (BMP-4), insulin receptor and Notch1 receptor. It also processes human immune deficiency virus 1 (HIV-1) glycoprotein gp160, several metalloproteases?and pro-β-nerve growth (pro-β-NGF) factor. Furin is also involved in cleaving transforming growth factor β1 (TGF-β1).

storage

Store at -20°C

FURIN INHIBITOR II Preparation Products And Raw materials

Raw materials

Preparation Products

FURIN INHIBITOR II Suppliers

Global( 69)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Zhejiang J&C Biological Technology Co.,Limited
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Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Hebei Miaoyin Technology Co.,Ltd
+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3582 58

View Lastest Price from FURIN INHIBITOR II manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FURIN INHIBITOR II pictures 2020-02-19 FURIN INHIBITOR II
673202-67-0
US $7.00 / KG 1KG 99% 100kg Career Henan Chemical Co
HEXA-D-ARGININE H-(D)RRRRRR-NH2 FURIN INHIBITOR II H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2 Hexa-D-arginine aMide D-ArgininamideD-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine Furin Inhibitor II, >98% Hexa-D-arginine,RRRRRR D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI) D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- inhibit,furin,Furin Inhibitor II,TNF-α,PACE4,noncytotoxic,PC1,anthrax,PEA,HexaDarginine,Hexa D arginine,exotoxins,Inhibitor Furin Inhibitor II(Hexa-D-arginine) 673202-67-0 C36H75N25O6