ChemicalBook >> CAS DataBase List >>TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN

CAS No.
98474-59-0
Chemical Name:
TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN
Synonyms
des-Gly77;MYELIN BASIC PROTEIN, FRAGMENT 68-82;MYELIN BASIC PROTEIN (68-82), GUINEA PIG;(Des-Gly77,Des-His78)-MBP (68-84) (bovine);MYELIN BASIC PROTEIN MBP (68-82), GUINEA PIG;MYELIN BASIC PROTEIN FRAGMENT 68-82 GUINEA PIG;myelin basic protein guinea pig fragment 68-82;(Des-Gly77,Des-His78)-MBP (68-84) (guinea pig);MBP (68-82),Myelin Basic Protein (68-84), guinea pig;DES[GLY77,HIS78]-MYELIN BASIC PROTEIN, FRAGMENT 68-64
CBNumber:
CB8721158
Molecular Formula:
C71H113N23O28
Molecular Weight:
1736.81
MDL Number:
MFCD00076872
MOL File:
98474-59-0.mol
MSDS File:
SDS
Last updated:2024-03-27 11:49:37

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN Properties

storage temp. -20°C
solubility insoluble in EtOH; ≥173.6 mg/mL in DMSO; ≥54.6 mg/mL in H2O
form solid
Sequence H-Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ser-Gln-Arg-Ser-Gln-Asp-Glu-Asn-OH

SAFETY

Risk and Safety Statements

WGK Germany  3

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M3755 Myelin Basic Protein Guinea Pig Fragment 68-82 ≥97% (HPLC) 98474-59-0 1mg $493.8 2024-03-01 Buy
Alfa Aesar J66176 Des-[Gly77, His78] Myelin Basic Protein (68-84), bovine 98474-59-0 1mg $109 2021-12-16 Buy
ApexBio Technology A1031 MyelinBasicProtein(68-82),guineapig 98474-59-0 10mg $110 2021-12-16 Buy
ApexBio Technology A1031 MyelinBasicProtein(68-82),guineapig 98474-59-0 25mg $154 2021-12-16 Buy
ApexBio Technology A1031 MyelinBasicProtein(68-82),guineapig 98474-59-0 5mg $66 2021-12-16 Buy
Product number Packaging Price Buy
M3755 1mg $493.8 Buy
J66176 1mg $109 Buy
A1031 10mg $110 Buy
A1031 25mg $154 Buy
A1031 5mg $66 Buy

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN Chemical Properties,Uses,Production

Biological Activity

myelin basic protein (68-82), guinea pig,(c71h113n23o28) is a peptide with the sequence tyr-gly-ser-leu-pro-gln-lys-ser-gln-arg-ser-gln-asp-glu-asn, mw= 1736.79. myelin basic protein (mbp) is a protein believed to be important in the process of myelination of nerves in the nervous system. knockout mice deficient in mbp showed decreased amounts of cns myelination and have developed a progressive disorder characterized by tremors, seizures, and early death. mbp research has centered on its role in demyelinating diseases, in particular, multiple sclerosis (ms). several studies have uncovered the role of antibodies against mbp in the pathogenesis of ms.] some studies have linked a genetic predisposition to ms to the mbp gene, though a majority have not. some recent work has shown that inoculating an animal with mbp to generate an immune response against it increases blood–brain barrier permeability.figure1 formula of myelin basic protein (68-82), guinea pigfigure2 structure of myelin basic protein

Biochem/physiol Actions

Myelin basic protein fragment that induces experimental allergic encephalomyelitis.

References

1. Sakamoto Y, Kitamura K, Yoshimura K, Nishijima T, Uyemura K (March 1987). "Complete amino acid sequence of POprotein in bovine peripheral nerve myelin". J. Biol. Chem. 262 (9): 4208–14.2. Deber CM, Reynolds SJ (April 1991). "Central nervous system myelin: structure, function, and pathology". Clin. Biochem. 24 (2): 113–34.3. Inouye H, Kirschner DA (January 1991). "Folding and function of the myelin proteins from primary sequence data". J. Neurosci. Res. 28 (1): 1–17.4. Berger T, Rubner P, Schautzer F, Egg R, Ulmer H, Mayringer I, Dilitz E, Deisenhammer F, Reindl M (July 2003). "Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event". N. Engl. J. Med. 349 (2): 139–45.

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN Preparation Products And Raw materials

Raw materials

Preparation Products

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN Suppliers

Global( 92)Suppliers
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Cellmano Biotech Limited
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TargetMol Chemicals Inc.
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Nanjing TGpeptide
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Zhejiang Hangyu API Co., Ltd
+8617531972939 anna@api-made.com China 2938 58

View Lastest Price from TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN pictures 2020-03-06 TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN
98474-59-0
US $1.00 / g 1g ≥98% g/kg/Ton Career Henan Chemical Co

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN Spectrum

DES[GLY77, HIS78]-SER75,80-MYELIN BASIC PROTEIN BOVINE FRAGMENT 68-84 TYR-GLY-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN TYR-GLY-SER-LEU-PRO-GLN-LYS-ALA-GLN-ARG-PRO-GLN-ASP-GLU-ASN TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN MYELIN BASIC PROTEIN, FRAGMENT 68-82 MYELIN BASIC PROTEIN FRAGMENT 68-82 GUINEA PIG MYELIN BASIC PROTEIN (68-82), GUINEA PIG des-gly77, des-his78-myelin basic protein bovine fragment 68-84 myelin basic protein guinea pig fragment 68-82 DES-GLY77, HIS78-MYELIN BASIC PROTEIN FRAGMENT 68-84 BOVINE MYELIN BASIC PROTEIN MBP (68-82), GUINEA PIG myelin, basic protein, fragment 68-84, des-Gly77, his78 des-Gly77 des-His78-Myelin Basic Protein Bovine fragment 68-84 (Des-Gly77,Des-His78)-Myelin Basic Protein (68-84) (guinea pig) (Des-Gly77,Des-His78)-MBP (68-84) (guinea pig) (Des-Gly77,Des-His78)-MBP (68-84) (bovine) (Des-Gly77,Des-His78)-MBP (68-84) (guinea pig) L-Tyrosylglycyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-lysyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-glutaminyl-L-alpha-aspartyl-L-alpha-glutamyl-L-asparagine H-TYR-GLY-SER-LEU-PRO-GLN-LYS-ALA-GLN-ARG-PRO-GLN-ASP-GLU-ASN-OH H-TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN-OH (DES-GLY77,DES-HIS78)-MYELIN BASIC PROTEIN (68-84) (BOVINE) (DES-GLY77,DES-HIS78)-MYELIN BASIC PROTEIN (68-84) (GUINEA PIG) DES-GLY77, DES-HIS78-MYELIN BASIC PROTEIN FRAGMENT 68-84 BOVINE DES-[GLY77,HIS78] MYELIN BASIC PROTEIN (68-84), BOVINE DES[GLY77,HIS78]-MYELIN BASIC PROTEIN, FRAGMENT 68-64 Myelin basic protein guinea pig fragment 68-82, ≥97% (HPLC) (Des-Gly77,Des-His78)-Myelin Basic Protein (68-84) (guinea pig) H-Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ser-Gln-Arg-Ser-Gln-Asp-Glu-Asn-OH TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN USP/EP/BP Myelin Basic Protein (MBP) (68-82), guinea pig,Inhibitor,inhibit,Myelin Basic Protein (MBP) (68 82), guinea pig,Myelin Basic Protein (MBP) (6882), guinea pig MBP (68-82),Myelin Basic Protein (68-84), guinea pig 98474-59-0 C73H115N23O26 Peptides Other Neuropeptides Miscellaneous Neuropeptides Biochemicals and Reagents BioChemical Amino Acids and Peptides Peptide Neuroscience