CARNOSOL
- CAS No.
- 5957-80-2
- Chemical Name:
- CARNOSOL
- Synonyms
- carnol;CARNOSOL;D-α-Alanine;CARNOSOL(RG);CARNOSOL USP/EP/BP;Carnosol, froM RoseMarinus officinalis;Carnosol, 98%, from Rosemarinus officinalis;1,3,4,9,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE;1,3,4,9,10,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE;1,2,3,4,4A,9,10,10AS-OCTAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISOPROPYL-9S, 4AR (EPOXYMETHANO)PHENANTHREN-12-ONE
- CBNumber:
- CB8736565
- Molecular Formula:
- C20H26O4
- Molecular Weight:
- 330.42
- MDL Number:
- MFCD02752467
- MOL File:
- 5957-80-2.mol
- MSDS File:
- SDS
| Melting point | 240～242℃ |
|---|---|
| Boiling point | 524.8±50.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO:66.0(Max Conc. mg/mL);199.74(Max Conc. mM) |
| pka | 8.91±0.40(Predicted) |
| color | White |
| LogP | 2.832 (est) |
| FDA UNII | 483O455CKD |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P280-P302+P352 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29322090 |
CARNOSOL price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C9617 | Carnosol | 5957-80-2 | 5mg | $380 | 2024-03-01 | Buy |
| Sigma-Aldrich | 49702 | Carnosol analytical standard | 5957-80-2 | 10mg | $747 | 2024-03-01 | Buy |
| Cayman Chemical | 89800 | Carnosol ≥96% | 5957-80-2 | 1mg | $45 | 2024-03-01 | Buy |
| Cayman Chemical | 89800 | Carnosol ≥96% | 5957-80-2 | 5mg | $198 | 2024-03-01 | Buy |
| Cayman Chemical | 89800 | Carnosol ≥96% | 5957-80-2 | 10mg | $351 | 2024-03-01 | Buy |
CARNOSOL Chemical Properties,Uses,Production
Description
Carnosol is a phytopolyphenol found in Rosemary that functions as an antioxidant, antimicrobial, & anticarcinogen.
Description
Carnosol is a phenol that has been found in rosemary (R. officinalis) and has diverse biological activities. It decreases nitric oxide (NO) production in mouse peritoneal exudate macrophages when used at concentrations ranging from 6 to 25 μM. Carnosol scavenges peroxyl and hydroxyl radicals and inhibits lipid peroxidation in cell-free assays. It inhibits 5-lipoxygenase (5-LO; IC50 = 0.1 μM for the recombinant human enzyme) and the synthesis of leukotrienes in human polymorphonuclear leukocytes (PMNs; IC50 = 7 μM). In vivo, carnosol (200 mg/kg) reduces mammary DNA adduct formation and tumorigenesis in a rat model of DMBA-induced mammary tumorigenesis.
Chemical Properties
White powder
Uses
Carnosol is a phytopolyphenol found in Rosemary that functions as an antioxidant, antimicrobial, & anticarcinogen.
Definition
ChEBI: Carnosol is a diterpenoid.
Cytotoxicity
IC50 (μg/mL): 65 (HL-60), 58 (K562), 50(Hep G2), 48 (MCF-7), 53 (MOLT-4)(Farimani et al. 2012)
IC50 (μg/mL): 61.46 (AGS) (Areche et al.2009)
IC50 (μg/mL): 2 (P388) (Aoyagi et al.2006)
IC50 (μg/mL): 1.19 (A2780), 3.30(SW1573), 8.59 (WiDr), 7.93 (T-47D),1.29 (HBL-100) (Guerrero et al. 2006).
CARNOSOL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 290 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
View Lastest Price from CARNOSOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | CARNOSOL
5957-80-2
|
US $0.00 / mg | 20mg | ≥98% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2024-04-22 | Carnosol
5957-80-2
|
US $0.00 / kg | 1kg | 99.8% | 1000 kg | BINBO BIOLOGICAL CO.,LTD | |
 |
2023-02-24 | Carnosol
5957-80-2
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
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