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Danofloxacin mesylate

CAS No.
119478-55-6
Chemical Name:
Danofloxacin mesylate
Synonyms
Advoci;Nofloxacin;CP-76136-27;Dafloxacin mesylate;Danofloxacin Mesylat;DANOFLOXACIN MESYLATE;DANOFLOXACIN MESULATE;DANOFLOXACIN MESILATE;Mesylate Danofloxacin;DANOFLOXANCIN MESYLATE
CBNumber:
CB8736590
Molecular Formula:
C20H24FN3O6S
Molecular Weight:
453.48
MDL Number:
MFCD00673687
MOL File:
119478-55-6.mol
Last updated:2024-04-03 17:07:09

Danofloxacin mesylate Properties

Melting point 337-339°C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Aqueous Base (Slightly, Sonicated), DMSO (Slightly, Sonicated)
form Solid
color White to Off-White
Stability Hygroscopic
CAS DataBase Reference 119478-55-6(CAS DataBase Reference)
FDA UNII 94F3SX3LEM

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H412-H373
Precautionary statements  P273-P501-P260-P314-P501
Safety Statements  24/25
HS Code  29339900

Danofloxacin mesylate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22408 Danofloxacin (mesylate) ≥98% 119478-55-6 50mg $44 2024-03-01 Buy
Cayman Chemical 22408 Danofloxacin (mesylate) ≥98% 119478-55-6 100mg $74 2024-03-01 Buy
Cayman Chemical 22408 Danofloxacin (mesylate) ≥98% 119478-55-6 250mg $172 2024-03-01 Buy
Cayman Chemical 22408 Danofloxacin (mesylate) ≥98% 119478-55-6 1g $469 2024-03-01 Buy
Usbiological 271209 Danofloxacin mesylate 119478-55-6 500mg $360 2021-12-16 Buy
Product number Packaging Price Buy
22408 50mg $44 Buy
22408 100mg $74 Buy
22408 250mg $172 Buy
22408 1g $469 Buy
271209 500mg $360 Buy

Danofloxacin mesylate Chemical Properties,Uses,Production

Description

Danofloxacin is a fluoroquinolone antibiotic and a type II topoisomerase inhibitor. It has a broad antimicrobial spectrum. It can be used as an anti-infective agent for veterinary use only.

Brand Name(s) in US

Advocin

Reference

J. A. Schrickx, J. Fink-Gremmels, Danofloxacin-mesylate is a substrate for ATP-dependent efflux transporters, British Journal of Pharmacology, 2009, vol. 150, pp. 463-469

Description

Danofloxacin is a fluoroquinolone antibiotic. In vitro, danofloxacin has activity against 68 field isolates of Mycoplasma species isolated from cattle, swine, and poultry with MICs ranging from 8 to 500 nM. It is protective in vivo against P. multocida, E. coli, and S. choleraesuis in mice with protective doses of 0.31, 0.40, and 2.42 mg/kg, respectively. Formulations containing danofloxacin are widely used to prevent infectious disease in livestock.

Chemical Properties

Crystalline Solid

Uses

Fluorinated quinolone antibacterial.

Uses

Danofloxacin is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM

Definition

ChEBI: Danofloxacin mesylate is a member of quinolines.

Veterinary Drugs and Treatments

Danofloxacin mesylate injection is indicated for the treatment of Bovine Respiratory Disease (BRD) associated with Mannheimia (Pasturella) hemolytica and P. multocida in cattle (not dairy or veal). Because of the drug’s spectrum of activity, it may also be of benefit in the treatment of infections caused by Histophilus somni (Haemophilus somnus) or M. bovis, but the drug is not labeled (at the time of writing) for treating these pathogens. In other countries, danofloxacin may be labeled for use in swine and chickens (non-laying), but in the USA it is illegal to use the drug in an extralabel manner in food-producing species.
Danofloxacin may be of benefit in treating susceptible infections in adult horses, camelids and other non-food producing species.

Danofloxacin mesylate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 242)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12457 58
shandong perfect biotechnology co.ltd
+86-53169958659; +8618596095638 sales@sdperfect.com China 294 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+86-13474506593 +86-13474506593 sarah@tnjone.com China 864 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
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18871490254 linda@hubeijusheng.com CHINA 28180 58
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CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Shaanxi Dideu Medichem Co. Ltd
18192627656 1012@dideu.com China 3453 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12477 58

View Lastest Price from Danofloxacin mesylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Danofloxacin Mesylate pictures 2024-04-05 Danofloxacin Mesylate
119478-55-6
US $0.00 / kg 1kg 99% 1000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
Danofloxacin Mesylate pictures 2024-03-12 Danofloxacin Mesylate
119478-55-6
US $0.00 / g 1g 98% HPLC 100kg shandong perfect biotechnology co.ltd
Danofloxacin mesylate pictures 2023-09-12 Danofloxacin mesylate
119478-55-6
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-quinolin-3-carboxylic acid methanesulfonate (1:1) 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-, methanesulfonate (1:1) Mesylate Dan Nuosha star DANOFLOXACIN MESILATE DANOFLOXACIN MESULATE DANOFLOXACIN MESYLATE DANOFLOXANCIN MESYLATE 1-cyclopropyl-6-fluoro-7-[(1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate Nofloxacin Advoci CP-76136-27 Danofloxacin Methanesulfonate 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-3-Quinolinecarboxylic Acid Mesylate Dafloxacin mesylate Danofloxacin Mesylat Danofloxacin Mesylate Dafloxacin Mesylate 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(5-Methyl-2,5-diazabicyclo[2.2.1]hept-2-yl)-4-oxo-, (1S)-, MonoMethanesulfonate Mesylate Danofloxacin Danofloxacin mesylate USP/EP/BP Danofloxacin Mesylate (CP 76136-27) TIANFU-CHEM - Danofloxacin mesylate Danofloxacin mesylate (DM), 98% 1-Cyclopropyl-6-fluoro-7-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonic acid salt 1-cyclopropyl-6-fluoro-7-(5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-oxo-3-quinolinecarboxylic acid 119478-55-6 C19H20FN3O3CH4O3S C20H24FN3O6S C19H20FN3O3CH3SO3H CH4O3SC19H20FN3O3 Intermediates & Fine Chemicals Pharmaceuticals