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Dibutyl sebacate

Dibutyl sebacate
Dibutyl sebacate structure
CAS No.
109-43-3
Chemical Name:
Dibutyl sebacate
Synonyms
RUBIN;px404;ROSEIN;PX 404;MAGENTA;NSC 3893;CL 42500;ReoMol D;MAGENTA O;ROSANILIN
CBNumber:
CB8737502
Molecular Formula:
C18H34O4
Formula Weight:
314.46
MOL File:
109-43-3.mol

Dibutyl sebacate Properties

Melting point:
205 °C (dec.)(lit.)
Boiling point:
178-179 °C3 mm Hg(lit.)
Density 
0.94
FEMA 
2373 | DIBUTYL SEBACATE
refractive index 
n20/D 1.441(lit.)
Flash point:
>230 °F
solubility 
hexane, toluene, ethanol and acetone: soluble
form 
Liquid
Specific Gravity
0.937 (20/4℃)
color 
Clear
Water Solubility 
50mg/L(temperature not stated)
JECFA Number
625
BRN 
1798308
CAS DataBase Reference
109-43-3(CAS DataBase Reference)
FDA 21 CFR
172.515; 175.105; 175.300; 175.320; 176.170; 177.2600; 178.3910; 181.27
Substances Added to Food (formerly EAFUS)
DIBUTYL SEBACATE
EWG's Food Scores
1
FDA UNII
4W5IH7FLNY
NIST Chemistry Reference
Di-n-butyl sebacate(109-43-3)
EPA Substance Registry System
Dibutyl sebacate (109-43-3)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  40-36/37/38
Safety Statements  36/37-36-26
WGK Germany  3
RTECS  VS1150000
TSCA  Yes
HS Code  29171390
Toxicity LD50 oral in rat: 14870mg/kg
NFPA 704
1
0 0

Dibutyl sebacate price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 80865 Dibutyl sebacate analytical standard 109-43-3 1ml $64.1 2021-03-22 Buy
Sigma-Aldrich 8.17067 Dibutyl sebacate NF 1 L $209 2021-03-22 Buy
Sigma-Aldrich 1187091 Dibutyl sebacate United States Pharmacopeia (USP) Reference Standard 109-43-3 1ml $414 2021-03-22 Buy
TCI Chemical S0023 Dibutyl Sebacate >98.0%(GC) 109-43-3 25mL $19 2021-03-22 Buy
TCI Chemical S0023 Dibutyl Sebacate >98.0%(GC) 109-43-3 500mL $59 2021-03-22 Buy

Dibutyl sebacate Chemical Properties,Uses,Production

Chemical Properties

clear liquid

Chemical Properties

Dibutyl sebacate is a clear, colorless, oily liquid with a bland to slight butyl odor.

Uses

Dibutyl sebacate (DBS) is a dibutyl ester of sebacic acid. Dibutyl sebacate can be used for plastics in use in the food packaging industry, in plastics used for medical devices, and for pharmaceutical applications. Dibutyl sebacate is also used as a desensitizer in Otto fuel II, a torpedo monopropellant.

Production Methods

Dibutyl sebacate is manufactured by the esterification of n-butanol and sebacic acid in the presence of a suitable catalyst, and by the distillation of sebacic acid with n-butanol in the presence of concentrated acid.

Preparation

By distillation of sebacic acid with butyl alcohol in the presence of concentrated HCl in benzene solution or by reacting butyl alcohol and sebacyl chloride

Pharmaceutical Applications

Dibutyl sebacate is used in oral pharmaceutical formulations as a plasticizer for film coatings on tablets, beads, and granules, at concentrations of 10–30% by weight of polymer. It is also used as a plasticizer in controlled-release tablets and microcapsule preparations.
Dibutyl sebacate is also used as a synthetic flavor and flavor adjuvant in food products;for example,up to 5ppm is used in ice cream and nonalcoholic beverages.

Safety Profile

Mddly toxic by ingestion. Experimental reproductive effects. Combustible liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use CO2 position it emits acrid smoke and fumes. See also ESTERS and n-BUTYL. ALCOHOL.

Safety

Dibutyl sebacate is used in cosmetics, foods, and oral pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material. Following oral administration, dibutyl sebacate is metabolized in the same way as fats. In humans, direct eye contact and prolonged or repeated contact with the skin may cause very mild irritation. Acute animal toxicity tests and long-term animal feeding studies have shown no serious adverse effects to be associated with orally administered dibutyl sebacate.
LD50 (rat, oral): 16g/kg

storage

Dibutyl sebacate should be stored in a closed container in a cool, dry location. Dibutyl sebacate is stable under the recommended storage conditions and as used in specified applications under most conditions ofuse.Asanester,dibutylsebacatemayhydrolyzeinthe presence of water at high or low pH conditions.

Incompatibilities

Dibutyl sebacate is incompatible with strong oxidizing materials and strong alkalis.

Regulatory Status

Included in the FDA Inactive Ingredients Database (oral capsules, granules, film-coated, sustained action, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Dibutyl sebacate Preparation Products And Raw materials

Raw materials

Preparation Products


Dibutyl sebacate Suppliers

Global( 277)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21535 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22608 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2813 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29991 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2928 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23036 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37042 58
Shaanxi Dideu Medichem Co. Ltd
18192627656
+86-29-88380327 1012@dideu.com CHINA 3948 58

View Lastest Price from Dibutyl sebacate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-01-17 Dibutyl Sebacate
109-43-3
US $1.00-0.00 / KG 1KG 99% 50 tons Shaanxi Dideu Medichem Co. Ltd
2018-12-19 Dibutyl sebacate
109-43-3
US $1.00 / kg 1kg as customer's need 1000kg career henan chemical co

Dibutyl sebacate Spectrum


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